BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 18443271)

  • 1. The effect of azacitidine on interleukin-6 signaling and nuclear factor-kappaB activation and its in vitro and in vivo activity against multiple myeloma.
    Khong T; Sharkey J; Spencer A
    Haematologica; 2008 Jun; 93(6):860-9. PubMed ID: 18443271
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL.
    Romagnoli M; Desplanques G; Maïga S; Legouill S; Dreano M; Bataille R; Barillé-Nion S
    Clin Cancer Res; 2007 Oct; 13(20):6010-8. PubMed ID: 17947462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cantharidin induces apoptosis of human multiple myeloma cells via inhibition of the JAK/STAT pathway.
    Sagawa M; Nakazato T; Uchida H; Ikeda Y; Kizaki M
    Cancer Sci; 2008 Sep; 99(9):1820-6. PubMed ID: 18544087
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo.
    Hideshima T; Neri P; Tassone P; Yasui H; Ishitsuka K; Raje N; Chauhan D; Podar K; Mitsiades C; Dang L; Munshi N; Richardson P; Schenkein D; Anderson KC
    Clin Cancer Res; 2006 Oct; 12(19):5887-94. PubMed ID: 17020997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity.
    Thyrell L; Arulampalam V; Hjortsberg L; Farnebo M; Grandér D; Pokrovskaja Tamm K
    Exp Cell Res; 2007 Nov; 313(19):4015-24. PubMed ID: 17880940
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
    Yasui H; Hideshima T; Raje N; Roccaro AM; Shiraishi N; Kumar S; Hamasaki M; Ishitsuka K; Tai YT; Podar K; Catley L; Mitsiades CS; Richardson PG; Albert R; Brinkmann V; Chauhan D; Anderson KC
    Cancer Res; 2005 Aug; 65(16):7478-84. PubMed ID: 16103102
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-kappaB inhibition and gene expression signature.
    Olivier S; Close P; Castermans E; de Leval L; Tabruyn S; Chariot A; Malaise M; Merville MP; Bours V; Franchimont N
    Mol Pharmacol; 2006 May; 69(5):1615-23. PubMed ID: 16497877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Blockage of interleukin-6 signaling with 6-amino-4-quinazoline synergistically induces the inhibitory effect of bortezomib in human U266 cells.
    Park J; Ahn KS; Bae EK; Kim BS; Kim BK; Lee YY; Yoon SS
    Anticancer Drugs; 2008 Sep; 19(8):777-82. PubMed ID: 18690088
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genistein down-regulates the constitutive activation of nuclear factor-kappaB in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis.
    He H; Chen L; Zhai M; Chen JZ
    Phytother Res; 2009 Jun; 23(6):868-73. PubMed ID: 19107739
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of interleukin-6 signaling with CNTO 328 enhances the activity of bortezomib in preclinical models of multiple myeloma.
    Voorhees PM; Chen Q; Kuhn DJ; Small GW; Hunsucker SA; Strader JS; Corringham RE; Zaki MH; Nemeth JA; Orlowski RZ
    Clin Cancer Res; 2007 Nov; 13(21):6469-78. PubMed ID: 17975159
    [TBL] [Abstract][Full Text] [Related]  

  • 11. OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms.
    Zhang S; Suvannasankha A; Crean CD; White VL; Johnson A; Chen CS; Farag SS
    Clin Cancer Res; 2007 Aug; 13(16):4750-8. PubMed ID: 17699852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo.
    Hsu YL; Kuo PL; Tzeng TF; Sung SC; Yen MH; Lin LT; Lin CC
    J Gastroenterol Hepatol; 2008 Jul; 23(7 Pt 2):e290-9. PubMed ID: 18522681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity.
    Nakaya A; Sagawa M; Muto A; Uchida H; Ikeda Y; Kizaki M
    Leuk Res; 2011 Feb; 35(2):243-9. PubMed ID: 20542334
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu In vivo model of human multiple myeloma.
    Tassone P; Neri P; Burger R; Savino R; Shammas M; Catley L; Podar K; Chauhan D; Masciari S; Gozzini A; Tagliaferri P; Venuta S; Munshi NC; Anderson KC
    Clin Cancer Res; 2005 Jun; 11(11):4251-8. PubMed ID: 15930364
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells.
    Bauer K; Kretzschmar AK; Cvijic H; Blumert C; Löffler D; Brocke-Heidrich K; Schiene-Fischer C; Fischer G; Sinz A; Clevenger CV; Horn F
    Oncogene; 2009 Aug; 28(31):2784-95. PubMed ID: 19503092
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Growth inhibition of multiple myeloma cells by a novel IkappaB kinase inhibitor.
    Sanda T; Iida S; Ogura H; Asamitsu K; Murata T; Bacon KB; Ueda R; Okamoto T
    Clin Cancer Res; 2005 Mar; 11(5):1974-82. PubMed ID: 15756023
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment.
    Tai YT; Li XF; Breitkreutz I; Song W; Neri P; Catley L; Podar K; Hideshima T; Chauhan D; Raje N; Schlossman R; Richardson P; Munshi NC; Anderson KC
    Cancer Res; 2006 Jul; 66(13):6675-82. PubMed ID: 16818641
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antimyeloma effects of a sesquiterpene lactone parthenolide.
    Suvannasankha A; Crean CD; Shanmugam R; Farag SS; Abonour R; Boswell HS; Nakshatri H
    Clin Cancer Res; 2008 Mar; 14(6):1814-22. PubMed ID: 18347184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.
    Gozzelino R; Sole C; Llecha N; Segura MF; Moubarak RS; Iglesias-Guimarais V; Perez-Garcia MJ; Reix S; Zhang J; Badiola N; Sanchis D; Rodriguez-Alvarez J; Trullas R; Yuste VJ; Comella JX
    Cell Res; 2008 Oct; 18(10):1020-36. PubMed ID: 18591962
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells.
    Liby K; Voong N; Williams CR; Risingsong R; Royce DB; Honda T; Gribble GW; Sporn MB; Letterio JJ
    Clin Cancer Res; 2006 Jul; 12(14 Pt 1):4288-93. PubMed ID: 16857804
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.