109 related articles for article (PubMed ID: 18445230)
1. Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42.
Qin W; Jia J
Eur J Neurosci; 2008 May; 27(9):2425-32. PubMed ID: 18445230
[TBL] [Abstract][Full Text] [Related]
2. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1.
Shimojo M; Sahara N; Murayama M; Ichinose H; Takashima A
Neurosci Res; 2007 Mar; 57(3):446-53. PubMed ID: 17210196
[TBL] [Abstract][Full Text] [Related]
3. Increase in p53 protein levels by presenilin 1 gene mutations and its inhibition by secretase inhibitors.
Ma L; Ohyagi Y; Miyoshi K; Sakae N; Motomura K; Taniwaki T; Furuya H; Takeda K; Tabira T; Kira J
J Alzheimers Dis; 2009; 16(3):565-75. PubMed ID: 19276551
[TBL] [Abstract][Full Text] [Related]
4. Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.
Vepsäläinen S; Hiltunen M; Helisalmi S; Wang J; van Groen T; Tanila H; Soininen H
Neurosci Lett; 2008 Jun; 438(2):216-20. PubMed ID: 18455870
[TBL] [Abstract][Full Text] [Related]
5. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
Farris W; Leissring MA; Hemming ML; Chang AY; Selkoe DJ
Biochemistry; 2005 May; 44(17):6513-25. PubMed ID: 15850385
[TBL] [Abstract][Full Text] [Related]
6. Elucidation of interactions of Alzheimer amyloid beta peptides (Abeta40 and Abeta42) with insulin degrading enzyme: a molecular dynamics study.
Bora RP; Prabhakar R
Biochemistry; 2010 May; 49(18):3947-56. PubMed ID: 20380468
[TBL] [Abstract][Full Text] [Related]
7. [The effect of two newly Chinese presenilin-1 mutations on the sensitivity to trophic factor withdrawal in human neuroblastoma cells].
Fang BY; Jia JP
Zhonghua Yi Xue Za Zhi; 2007 Jan; 87(5):336-40. PubMed ID: 17456364
[TBL] [Abstract][Full Text] [Related]
8. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
Zatti G; Burgo A; Giacomello M; Barbiero L; Ghidoni R; Sinigaglia G; Florean C; Bagnoli S; Binetti G; Sorbi S; Pizzo P; Fasolato C
Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
[TBL] [Abstract][Full Text] [Related]
9. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.
Zhao Z; Xiang Z; Haroutunian V; Buxbaum JD; Stetka B; Pasinetti GM
Neurobiol Aging; 2007 Jun; 28(6):824-30. PubMed ID: 16769157
[TBL] [Abstract][Full Text] [Related]
10. Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
Blomqvist ME; Chalmers K; Andreasen N; Bogdanovic N; Wilcock GK; Cairns NJ; Feuk L; Brookes AJ; Love S; Blennow K; Kehoe PG; Prince JA
Neurobiol Aging; 2005 Jun; 26(6):795-802. PubMed ID: 15718037
[TBL] [Abstract][Full Text] [Related]
11. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
Kumar VB; Franko M; Banks WA; Kasinadhuni P; Farr SA; Vyas K; Choudhuri V; Morley JE
J Exp Biol; 2009 Feb; 212(Pt 4):494-8. PubMed ID: 19181896
[TBL] [Abstract][Full Text] [Related]
12. Chinese Presenilin-1 V97L mutation enhanced Abeta42 levels in SH-SY5Y neuroblastoma cells.
Fang B; Jia L; Jia J
Neurosci Lett; 2006 Oct; 406(1-2):33-7. PubMed ID: 16916581
[TBL] [Abstract][Full Text] [Related]
13. Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.
Uemura K; Kitagawa N; Kohno R; Kuzuya A; Kageyama T; Chonabayashi K; Shibasaki H; Shimohama S
J Neurosci Res; 2003 Oct; 74(2):184-91. PubMed ID: 14515347
[TBL] [Abstract][Full Text] [Related]
14. Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila.
Tsuda M; Kobayashi T; Matsuo T; Aigaki T
FEBS Lett; 2010 Jul; 584(13):2916-20. PubMed ID: 20493190
[TBL] [Abstract][Full Text] [Related]
15. Mean age of onset in familial Alzheimer's disease is determined by amyloid beta 42.
Duering M; Grimm MO; Grimm HS; Schröder J; Hartmann T
Neurobiol Aging; 2005 Jun; 26(6):785-8. PubMed ID: 15718035
[TBL] [Abstract][Full Text] [Related]
16. Insulin degrading enzyme is localized predominantly at the cell surface of polarized and unpolarized human cerebrovascular endothelial cell cultures.
Lynch JA; George AM; Eisenhauer PB; Conn K; Gao W; Carreras I; Wells JM; McKee A; Ullman MD; Fine RE
J Neurosci Res; 2006 May; 83(7):1262-70. PubMed ID: 16511862
[TBL] [Abstract][Full Text] [Related]
17. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
Lin HC; Hsieh HM; Chen YH; Hu ML
Neurotoxicology; 2009 Jul; 30(4):622-7. PubMed ID: 19635394
[TBL] [Abstract][Full Text] [Related]
18. Cytosolic amyloid-beta peptide 42 escaping from degradation induces cell death.
Lee EK; Park YW; Shin DY; Mook-Jung I; Yoo YJ
Biochem Biophys Res Commun; 2006 Jun; 344(2):471-7. PubMed ID: 16630565
[TBL] [Abstract][Full Text] [Related]
19. miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation.
Wang X; Liu P; Zhu H; Xu Y; Ma C; Dai X; Huang L; Liu Y; Zhang L; Qin C
Brain Res Bull; 2009 Oct; 80(4-5):268-73. PubMed ID: 19683563
[TBL] [Abstract][Full Text] [Related]
20. Promoter polymorphisms which modulate insulin degrading enzyme expression may increase susceptibility to Alzheimer's disease.
Zuo X; Jia J
Brain Res; 2009 Jan; 1249():1-8. PubMed ID: 18996360
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]