BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

419 related articles for article (PubMed ID: 18445495)

  • 1. LRRK2 regulates synaptic vesicle endocytosis.
    Shin N; Jeong H; Kwon J; Heo HY; Kwon JJ; Yun HJ; Kim CH; Han BS; Tong Y; Shen J; Hatano T; Hattori N; Kim KS; Chang S; Seol W
    Exp Cell Res; 2008 Jun; 314(10):2055-65. PubMed ID: 18445495
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.
    Pan PY; Li X; Wang J; Powell J; Wang Q; Zhang Y; Chen Z; Wicinski B; Hof P; Ryan TA; Yue Z
    J Neurosci; 2017 Nov; 37(47):11366-11376. PubMed ID: 29054882
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An early endosome regulator, Rab5b, is an LRRK2 kinase substrate.
    Yun HJ; Kim H; Ga I; Oh H; Ho DH; Kim J; Seo H; Son I; Seol W
    J Biochem; 2015 Jun; 157(6):485-95. PubMed ID: 25605758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila.
    Inoshita T; Arano T; Hosaka Y; Meng H; Umezaki Y; Kosugi S; Morimoto T; Koike M; Chang HY; Imai Y; Hattori N
    Hum Mol Genet; 2017 Aug; 26(15):2933-2948. PubMed ID: 28482024
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.
    Stafa K; Tsika E; Moser R; Musso A; Glauser L; Jones A; Biskup S; Xiong Y; Bandopadhyay R; Dawson VL; Dawson TM; Moore DJ
    Hum Mol Genet; 2014 Apr; 23(8):2055-77. PubMed ID: 24282027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.
    MacLeod DA; Rhinn H; Kuwahara T; Zolin A; Di Paolo G; McCabe BD; Marder KS; Honig LS; Clark LN; Small SA; Abeliovich A
    Neuron; 2013 Feb; 77(3):425-39. PubMed ID: 23395371
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.
    Piccoli G; Onofri F; Cirnaru MD; Kaiser CJ; Jagtap P; Kastenmüller A; Pischedda F; Marte A; von Zweydorf F; Vogt A; Giesert F; Pan L; Antonucci F; Kiel C; Zhang M; Weinkauf S; Sattler M; Sala C; Matteoli M; Ueffing M; Gloeckner CJ
    Mol Cell Biol; 2014 Jun; 34(12):2147-61. PubMed ID: 24687852
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease.
    Nguyen M; Krainc D
    Proc Natl Acad Sci U S A; 2018 May; 115(21):5576-5581. PubMed ID: 29735704
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LRRK2 at the pre-synaptic site: A 16-years perspective.
    Pischedda F; Piccoli G
    J Neurochem; 2021 Apr; 157(2):297-311. PubMed ID: 33206398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
    Heaton GR; Landeck N; Mamais A; Nalls MA; Nixon-Abell J; Kumaran R; Beilina A; Pellegrini L; Li Y; ; Harvey K; Cookson MR
    Neurobiol Dis; 2020 Jul; 141():104948. PubMed ID: 32434048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism.
    Arranz AM; Delbroek L; Van Kolen K; Guimarães MR; Mandemakers W; Daneels G; Matta S; Calafate S; Shaban H; Baatsen P; De Bock PJ; Gevaert K; Vanden Berghe P; Verstreken P; De Strooper B; Moechars D
    J Cell Sci; 2015 Feb; 128(3):541–52. PubMed ID: 25501810
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.
    Matta S; Van Kolen K; da Cunha R; van den Bogaart G; Mandemakers W; Miskiewicz K; De Bock PJ; Morais VA; Vilain S; Haddad D; Delbroek L; Swerts J; Chávez-Gutiérrez L; Esposito G; Daneels G; Karran E; Holt M; Gevaert K; Moechars DW; De Strooper B; Verstreken P
    Neuron; 2012 Sep; 75(6):1008-21. PubMed ID: 22998870
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.
    Cho HJ; Liu G; Jin SM; Parisiadou L; Xie C; Yu J; Sun L; Ma B; Ding J; Vancraenenbroeck R; Lobbestael E; Baekelandt V; Taymans JM; He P; Troncoso JC; Shen Y; Cai H
    Hum Mol Genet; 2013 Feb; 22(3):608-20. PubMed ID: 23125283
    [TBL] [Abstract][Full Text] [Related]  

  • 14. LRRK2 and the Endolysosomal System in Parkinson's Disease.
    Erb ML; Moore DJ
    J Parkinsons Dis; 2020; 10(4):1271-1291. PubMed ID: 33044192
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.
    Yun HJ; Park J; Ho DH; Kim H; Kim CH; Oh H; Ga I; Seo H; Chang S; Son I; Seol W
    Exp Mol Med; 2013 Aug; 45(8):e36. PubMed ID: 23949442
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LRRK2 and vesicle trafficking.
    Sanna G; Del Giudice MG; Crosio C; Iaccarino C
    Biochem Soc Trans; 2012 Oct; 40(5):1117-22. PubMed ID: 22988875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1.
    Stafa K; Trancikova A; Webber PJ; Glauser L; West AB; Moore DJ
    PLoS Genet; 2012; 8(2):e1002526. PubMed ID: 22363216
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2.
    Connor-Robson N; Booth H; Martin JG; Gao B; Li K; Doig N; Vowles J; Browne C; Klinger L; Juhasz P; Klein C; Cowley SA; Bolam P; Hirst W; Wade-Martins R
    Neurobiol Dis; 2019 Jul; 127():512-526. PubMed ID: 30954703
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel insights into the neurobiology underlying LRRK2-linked Parkinson's disease.
    Gómez-Suaga P; Fdez E; Fernández B; Martínez-Salvador M; Blanca Ramírez M; Madero-Pérez J; Rivero-Ríos P; Fuentes JM; Hilfiker S
    Neuropharmacology; 2014 Oct; 85():45-56. PubMed ID: 24863040
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The synaptic function of LRRK2.
    Lee S; Imai Y; Gehrke S; Liu S; Lu B
    Biochem Soc Trans; 2012 Oct; 40(5):1047-51. PubMed ID: 22988863
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.