These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 18445579)

  • 1. Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry.
    Zabrouskov V; Ge Y; Schwartz J; Walker JW
    Mol Cell Proteomics; 2008 Oct; 7(10):1838-49. PubMed ID: 18445579
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated.
    Ayaz-Guner S; Zhang J; Li L; Walker JW; Ge Y
    Biochemistry; 2009 Sep; 48(34):8161-70. PubMed ID: 19637843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top-down tandem mass spectrometry.
    Sancho Solis R; Ge Y; Walker JW
    J Muscle Res Cell Motil; 2008; 29(6-8):203-12. PubMed ID: 19165611
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deciphering modifications in swine cardiac troponin I by top-down high-resolution tandem mass spectrometry.
    Zhang J; Dong X; Hacker TA; Ge Y
    J Am Soc Mass Spectrom; 2010 Jun; 21(6):940-8. PubMed ID: 20223681
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Augmented phosphorylation of cardiac troponin I in hypertensive heart failure.
    Dong X; Sumandea CA; Chen YC; Garcia-Cazarin ML; Zhang J; Balke CW; Sumandea MP; Ge Y
    J Biol Chem; 2012 Jan; 287(2):848-57. PubMed ID: 22052912
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1.
    You B; Yan G; Zhang Z; Yan L; Li J; Ge Q; Jin JP; Sun J
    Biochem J; 2009 Feb; 418(1):93-101. PubMed ID: 18986304
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure.
    Zhang J; Guy MJ; Norman HS; Chen YC; Xu Q; Dong X; Guner H; Wang S; Kohmoto T; Young KH; Moss RL; Ge Y
    J Proteome Res; 2011 Sep; 10(9):4054-65. PubMed ID: 21751783
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation, but not alternative splicing or proteolytic degradation, is conserved in human and mouse cardiac troponin T.
    Zhang J; Zhang H; Ayaz-Guner S; Chen YC; Dong X; Xu Q; Ge Y
    Biochemistry; 2011 Jul; 50(27):6081-92. PubMed ID: 21639091
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation-induced distance change in a cardiac muscle troponin I mutant.
    Dong WJ; Chandra M; Xing J; She M; Solaro RJ; Cheung HC
    Biochemistry; 1997 Jun; 36(22):6754-61. PubMed ID: 9184157
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comprehensive Characterization of Swine Cardiac Troponin T Proteoforms by Top-Down Mass Spectrometry.
    Lin Z; Guo F; Gregorich ZR; Sun R; Zhang H; Hu Y; Shanmuganayagam D; Ge Y
    J Am Soc Mass Spectrom; 2018 Jun; 29(6):1284-1294. PubMed ID: 29633223
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of cardiac troponin proteoforms by top-down mass spectrometry.
    Tiambeng TN; Tucholski T; Wu Z; Zhu Y; Mitchell SD; Roberts DS; Jin Y; Ge Y
    Methods Enzymol; 2019; 626():347-374. PubMed ID: 31606082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments.
    Lu QW; Hinken AC; Patrick SE; Solaro RJ; Kobayashi T
    J Biol Chem; 2010 Apr; 285(16):11810-7. PubMed ID: 20164197
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The heart-specific NH2-terminal extension regulates the molecular conformation and function of cardiac troponin I.
    Akhter S; Zhang Z; Jin JP
    Am J Physiol Heart Circ Physiol; 2012 Feb; 302(4):H923-33. PubMed ID: 22140044
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy.
    Wang Y; Pinto JR; Solis RS; Dweck D; Liang J; Diaz-Perez Z; Ge Y; Walker JW; Potter JD
    J Biol Chem; 2012 Jan; 287(3):2156-67. PubMed ID: 22086914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca2+ affinity of cardiac troponin C.
    Zhang R; Zhao J; Potter JD
    J Biol Chem; 1995 Dec; 270(51):30773-80. PubMed ID: 8530519
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C.
    Kobayashi T; Yang X; Walker LA; Van Breemen RB; Solaro RJ
    J Mol Cell Cardiol; 2005 Jan; 38(1):213-8. PubMed ID: 15623438
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Impact of Phosphorylation on Electron Capture Dissociation of Proteins: A Top-Down Perspective.
    Chen B; Guo X; Tucholski T; Lin Z; McIlwain S; Ge Y
    J Am Soc Mass Spectrom; 2017 Sep; 28(9):1805-1814. PubMed ID: 28685494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
    Wijnker PJ; Li Y; Zhang P; Foster DB; dos Remedios C; Van Eyk JE; Stienen GJ; Murphy AM; van der Velden J
    J Mol Cell Cardiol; 2015 May; 82():93-103. PubMed ID: 25771144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of the acidic N' region of cardiac troponin I in regulating myocardial function.
    Sadayappan S; Finley N; Howarth JW; Osinska H; Klevitsky R; Lorenz JN; Rosevear PR; Robbins J
    FASEB J; 2008 Apr; 22(4):1246-57. PubMed ID: 17984178
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A preferred AMPK phosphorylation site adjacent to the inhibitory loop of cardiac and skeletal troponin I.
    Sancho Solis R; Ge Y; Walker JW
    Protein Sci; 2011 May; 20(5):894-907. PubMed ID: 21416543
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.