BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 18448069)

  • 1. AIMP1/p43 downregulates TGF-beta signaling via stabilization of smurf2.
    Lee YS; Han JM; Son SH; Choi JW; Jeon EJ; Bae SC; Park YI; Kim S
    Biochem Biophys Res Commun; 2008 Jul; 371(3):395-400. PubMed ID: 18448069
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD109-mediated degradation of TGF-β receptors and inhibition of TGF-β responses involve regulation of SMAD7 and Smurf2 localization and function.
    Bizet AA; Tran-Khanh N; Saksena A; Liu K; Buschmann MD; Philip A
    J Cell Biochem; 2012 Jan; 113(1):238-46. PubMed ID: 21898545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).
    Komuro A; Imamura T; Saitoh M; Yoshida Y; Yamori T; Miyazono K; Miyazawa K
    Oncogene; 2004 Sep; 23(41):6914-23. PubMed ID: 15221015
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal.
    Ahn J; Kumar H; Cha BH; Park S; Arai Y; Han I; Park SG; Lee SH
    Cell Death Dis; 2016 Feb; 7(2):e2099. PubMed ID: 26890138
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins.
    Nakano A; Koinuma D; Miyazawa K; Uchida T; Saitoh M; Kawabata M; Hanai J; Akiyama H; Abe M; Miyazono K; Matsumoto T; Imamura T
    J Biol Chem; 2009 Mar; 284(10):6109-15. PubMed ID: 19122240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional induction of Smurf2 ubiquitin ligase by TGF-beta.
    Ohashi N; Yamamoto T; Uchida C; Togawa A; Fukasawa H; Fujigaki Y; Suzuki S; Kitagawa K; Hattori T; Oda T; Hayashi H; Hishida A; Kitagawa M
    FEBS Lett; 2005 May; 579(12):2557-63. PubMed ID: 15862290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.
    Yan X; Liao H; Cheng M; Shi X; Lin X; Feng XH; Chen YG
    J Biol Chem; 2016 Jan; 291(1):382-92. PubMed ID: 26555259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.
    Hanyu A; Ishidou Y; Ebisawa T; Shimanuki T; Imamura T; Miyazono K
    J Cell Biol; 2001 Dec; 155(6):1017-27. PubMed ID: 11739411
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Degradation of AIMP1/p43 induced by hepatitis C virus E2 leads to upregulation of TGF-β signaling and increase in surface expression of gp96.
    Kim MS; Kim S; Myung H
    PLoS One; 2014; 9(5):e96302. PubMed ID: 24816397
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.
    Fukasawa H; Yamamoto T; Togawa A; Ohashi N; Fujigaki Y; Oda T; Uchida C; Kitagawa K; Hattori T; Suzuki S; Kitagawa M; Hishida A
    Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8687-92. PubMed ID: 15173588
    [TBL] [Abstract][Full Text] [Related]  

  • 12. USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7.
    Kit Leng Lui S; Iyengar PV; Jaynes P; Isa ZFBA; Pang B; Tan TZ; Eichhorn PJA
    EMBO Rep; 2017 May; 18(5):797-808. PubMed ID: 28381482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.
    Malonis RJ; Fu W; Jelcic MJ; Thompson M; Canter BS; Tsikitis M; Esteva FJ; Sánchez I
    J Biol Chem; 2017 May; 292(18):7435-7451. PubMed ID: 28292929
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of Smad ubiquitin regulatory factor 2 suppresses transforming growth factor-β mediated liver fibrosis.
    Cai Y; Zhou CH; Fu D; Shen XZ
    J Dig Dis; 2012 Jun; 13(6):327-34. PubMed ID: 22624557
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effects of WW2/WW3 domains of Smurf2 molecule on TGF-β signaling and arginase I gene expression.
    Ganji A; Roshan HM; Varasteh A; Moghadam M; Sankian M
    Cell Biol Int; 2015 Jun; 39(6):690-5. PubMed ID: 25612247
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SMURF2 and SMAD7 induce SARA degradation via the proteasome.
    Wojtowicz S; Lee S; Chan E; Ng E; Campbell CI; Di Guglielmo GM
    Cell Signal; 2020 Aug; 72():109627. PubMed ID: 32283253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aminoacyl-tRNA synthetase interacting multi-functional protein 1 attenuates liver fibrosis by inhibiting TGFβ signaling.
    Ahn J; Son MK; Jung KH; Kim K; Kim GJ; Lee SH; Hong SS; Park SG
    Int J Oncol; 2016 Feb; 48(2):747-55. PubMed ID: 26692190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Itch E3 ubiquitin ligase positively regulates TGF-β signaling to EMT via Smad7 ubiquitination.
    Park SH; Jung EH; Kim GY; Kim BC; Lim JH; Woo CH
    Mol Cells; 2015 Jan; 38(1):20-5. PubMed ID: 25518932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis.
    Liu FY; Li XZ; Peng YM; Liu H; Liu YH
    Am J Nephrol; 2007; 27(2):176-83. PubMed ID: 17347560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Smad7 down-regulation via ubiquitin degradation mediated by Smurf2 in fibroblasts of hypertrophic scars in burned patients.
    Zhang Z; Liu C; Chen B; Tang W; Liu Z; Cao W; Li X
    Burns; 2021 Sep; 47(6):1333-1341. PubMed ID: 33436154
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.