429 related articles for article (PubMed ID: 18451267)
1. The serine protease TMPRSS6 is required to sense iron deficiency.
Du X; She E; Gelbart T; Truksa J; Lee P; Xia Y; Khovananth K; Mudd S; Mann N; Moresco EM; Beutler E; Beutler B
Science; 2008 May; 320(5879):1088-92. PubMed ID: 18451267
[TBL] [Abstract][Full Text] [Related]
2. A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron.
Melis MA; Cau M; Congiu R; Sole G; Barella S; Cao A; Westerman M; Cazzola M; Galanello R
Haematologica; 2008 Oct; 93(10):1473-9. PubMed ID: 18603562
[TBL] [Abstract][Full Text] [Related]
3. Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.
Nai A; Pagani A; Mandelli G; Lidonnici MR; Silvestri L; Ferrari G; Camaschella C
Blood; 2012 May; 119(21):5021-9. PubMed ID: 22490684
[TBL] [Abstract][Full Text] [Related]
4. Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.
Finberg KE; Whittlesey RL; Andrews NC
Blood; 2011 Apr; 117(17):4590-9. PubMed ID: 21355094
[TBL] [Abstract][Full Text] [Related]
5. A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA.
Altamura S; D'Alessio F; Selle B; Muckenthaler MU
Biochem J; 2010 Nov; 431(3):363-71. PubMed ID: 20704562
[TBL] [Abstract][Full Text] [Related]
6. Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.
Meynard D; Vaja V; Sun CC; Corradini E; Chen S; López-Otín C; Grgurevic L; Hong CC; Stirnberg M; Gütschow M; Vukicevic S; Babitt JL; Lin HY
Blood; 2011 Jul; 118(3):747-56. PubMed ID: 21622652
[TBL] [Abstract][Full Text] [Related]
7. Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.
Lakhal S; Schödel J; Townsend AR; Pugh CW; Ratcliffe PJ; Mole DR
J Biol Chem; 2011 Feb; 286(6):4090-7. PubMed ID: 20966077
[TBL] [Abstract][Full Text] [Related]
8. Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6.
Truksa J; Gelbart T; Peng H; Beutler E; Beutler B; Lee P
Br J Haematol; 2009 Nov; 147(4):571-81. PubMed ID: 19751239
[TBL] [Abstract][Full Text] [Related]
9. The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin.
Silvestri L; Pagani A; Nai A; De Domenico I; Kaplan J; Camaschella C
Cell Metab; 2008 Dec; 8(6):502-11. PubMed ID: 18976966
[TBL] [Abstract][Full Text] [Related]
10. Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.
Guo S; Casu C; Gardenghi S; Booten S; Aghajan M; Peralta R; Watt A; Freier S; Monia BP; Rivella S
J Clin Invest; 2013 Apr; 123(4):1531-41. PubMed ID: 23524968
[TBL] [Abstract][Full Text] [Related]
11. Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.
Lenoir A; Deschemin JC; Kautz L; Ramsay AJ; Roth MP; Lopez-Otin C; Vaulont S; Nicolas G
Blood; 2011 Jan; 117(2):647-50. PubMed ID: 20940420
[TBL] [Abstract][Full Text] [Related]
12. Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
Finberg KE; Whittlesey RL; Fleming MD; Andrews NC
Blood; 2010 May; 115(18):3817-26. PubMed ID: 20200349
[TBL] [Abstract][Full Text] [Related]
13. Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6).
Krijt J; Fujikura Y; Ramsay AJ; Velasco G; Nečas E
Blood Cells Mol Dis; 2011 Aug; 47(2):133-7. PubMed ID: 21612955
[TBL] [Abstract][Full Text] [Related]
14. Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis.
Folgueras AR; de Lara FM; Pendás AM; Garabaya C; Rodríguez F; Astudillo A; Bernal T; Cabanillas R; López-Otín C; Velasco G
Blood; 2008 Sep; 112(6):2539-45. PubMed ID: 18523150
[TBL] [Abstract][Full Text] [Related]
15. Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality.
Béliveau F; Brulé C; Désilets A; Zimmerman B; Laporte SA; Lavoie CL; Leduc R
J Biol Chem; 2011 Aug; 286(33):29035-29043. PubMed ID: 21724843
[TBL] [Abstract][Full Text] [Related]
16. A novel mutation Gly603Arg of TMPRSS6 in a Korean female with iron-refractory iron deficiency anemia.
Choi HS; Yang HR; Song SH; Seo JY; Lee KO; Kim HJ
Pediatr Blood Cancer; 2012 Apr; 58(4):640-2. PubMed ID: 21618415
[TBL] [Abstract][Full Text] [Related]
17. Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies.
De Falco L; Silvestri L; Kannengiesser C; Morán E; Oudin C; Rausa M; Bruno M; Aranda J; Argiles B; Yenicesu I; Falcon-Rodriguez M; Yilmaz-Keskin E; Kocak U; Beaumont C; Camaschella C; Iolascon A; Grandchamp B; Sanchez M
Hum Mutat; 2014 Nov; 35(11):1321-9. PubMed ID: 25156943
[TBL] [Abstract][Full Text] [Related]
18. TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals.
Nai A; Pagani A; Silvestri L; Campostrini N; Corbella M; Girelli D; Traglia M; Toniolo D; Camaschella C
Blood; 2011 Oct; 118(16):4459-62. PubMed ID: 21873547
[TBL] [Abstract][Full Text] [Related]
19. Iron-deficiency anemia secondary to mutations in genes controlling hepcidin.
Cau M; Melis MA; Congiu R; Galanello R
Expert Rev Hematol; 2010 Apr; 3(2):205-16. PubMed ID: 21083463
[TBL] [Abstract][Full Text] [Related]
20. Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.
Frýdlová J; Rychtarčíková Z; Gurieva I; Vokurka M; Truksa J; Krijt J
PLoS One; 2017; 12(10):e0186844. PubMed ID: 29073189
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]