BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 18455811)

  • 1. Substrate specificity of feline and canine herpesvirus thymidine kinase.
    Solaroli N; Johansson M; Persoons L; Balzarini J; Karlsson A
    Antiviral Res; 2008 Aug; 79(2):128-32. PubMed ID: 18455811
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization and susceptibility to antiviral agents of herpes simplex virus type 1 containing a unique thymidine kinase gene with an amber codon between the first and the second initiation codons.
    Saijo M; Suzutani T; Mizuta K; Kurane I; Morikawa S
    Arch Virol; 2008; 153(2):303-14. PubMed ID: 18066636
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate specificity of three viral thymidine kinases (TK): vaccinia virus TK, feline herpesvirus TK, and canine herpesvirus TK.
    Solaroli N; Johansson M; Balzarini J; Karlsson A
    Nucleosides Nucleotides Nucleic Acids; 2006; 25(9-11):1189-92. PubMed ID: 17065088
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.
    Hussein IT; Miguel RN; Tiley LS; Field HJ
    Arch Virol; 2008; 153(3):495-505. PubMed ID: 18196203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thymidylate synthase is the principal target enzyme for the cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine against murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 or type 2 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Shimizu K; Seno T
    Mol Pharmacol; 1987 Sep; 32(3):410-6. PubMed ID: 2823092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active: interaction of the (+)- and (-)-enantiomers of C-IDU and C-BVDU with the thymidine kinase of herpes simplex virus type 1.
    Balzarini J; De Clercq E; Baumgartner H; Bodenteich M; Griengl H
    Mol Pharmacol; 1990 Mar; 37(3):395-401. PubMed ID: 2156153
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Highly selective cytostatic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine derivatives for murine mammary carcinoma (FM3A) cells transformed with the herpes simplex virus type 1 thymidine kinase gene.
    Balzarini J; De Clercq E; Verbruggen A; Ayusawa D; Seno T
    Mol Pharmacol; 1985 Dec; 28(6):581-7. PubMed ID: 3001499
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
    Degrève B; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2001 Feb; 59(2):285-93. PubMed ID: 11160865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of nucleoside analogs by equine herpesvirus type 1 pyrimidine deoxyribonucleoside kinase.
    Kit S; Ichimura H; De Clercq E
    Antiviral Res; 1987 Jan; 7(1):53-67. PubMed ID: 3026247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
    Balzarini J; De Clercq E; Verbruggen A; Crumpacker C; Ayusawa D; Seno T
    Anticancer Res; 1986; 6(5):1077-84. PubMed ID: 2432829
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Wilber BA; Docherty JJ
    J Gen Virol; 1994 Jul; 75 ( Pt 7)():1743-7. PubMed ID: 8021603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Channel catfish herpesvirus (CCV) encodes a functional thymidine kinase gene: elucidation of a point mutation that confers resistance to Ara-T.
    Hanson LA; Kousoulas KG; Thune RL
    Virology; 1994 Aug; 202(2):659-64. PubMed ID: 8030231
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Penciclovir is a potent inhibitor of feline herpesvirus-1 with susceptibility determined at the level of virus-encoded thymidine kinase.
    Hussein IT; Menashy RV; Field HJ
    Antiviral Res; 2008 Jun; 78(3):268-74. PubMed ID: 18325606
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity.
    Balzarini J; Van Daele I; Negri A; Solaroli N; Karlsson A; Liekens S; Gago F; Van Calenbergh S
    Mol Pharmacol; 2009 May; 75(5):1127-36. PubMed ID: 19233899
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase.
    Sienaert R; Naesens L; Brancale A; De Clercq E; McGuigan C; Balzarini J
    Mol Pharmacol; 2002 Feb; 61(2):249-54. PubMed ID: 11809847
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs.
    Prichard MN; Williams AD; Keith KA; Harden EA; Kern ER
    Antiviral Res; 2006 Aug; 71(1):1-6. PubMed ID: 16530858
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies.
    Spadari S; Ciarrocchi G; Focher F; Verri A; Maga G; Arcamone F; Iafrate E; Manzini S; Garbesi A; Tondelli L
    Mol Pharmacol; 1995 Jun; 47(6):1231-8. PubMed ID: 7603465
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion.
    Li J; Le L; Sibley DA; Mathis JM; Curiel DT
    Virology; 2005 Aug; 338(2):247-58. PubMed ID: 15996701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase.
    Balzarini J; Hernández AI; Roche P; Esnouf R; Karlsson A; Camarasa MJ; Pérez-Pérez MJ
    Mol Pharmacol; 2003 Feb; 63(2):263-70. PubMed ID: 12527796
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling.
    Christians FC; Scapozza L; Crameri A; Folkers G; Stemmer WP
    Nat Biotechnol; 1999 Mar; 17(3):259-64. PubMed ID: 10096293
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.