210 related articles for article (PubMed ID: 18458110)
1. Degradation of functional triose phosphate isomerase protein underlies sugarkill pathology.
Seigle JL; Celotto AM; Palladino MJ
Genetics; 2008 Jun; 179(2):855-62. PubMed ID: 18458110
[TBL] [Abstract][Full Text] [Related]
2. Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila.
Hrizo SL; Palladino MJ
Neurobiol Dis; 2010 Dec; 40(3):676-83. PubMed ID: 20727972
[TBL] [Abstract][Full Text] [Related]
3. Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity.
Roland BP; Stuchul KA; Larsen SB; Amrich CG; Vandemark AP; Celotto AM; Palladino MJ
J Cell Sci; 2013 Jul; 126(Pt 14):3151-8. PubMed ID: 23641070
[TBL] [Abstract][Full Text] [Related]
4. Drosophila model of human inherited triosephosphate isomerase deficiency glycolytic enzymopathy.
Celotto AM; Frank AC; Seigle JL; Palladino MJ
Genetics; 2006 Nov; 174(3):1237-46. PubMed ID: 16980388
[TBL] [Abstract][Full Text] [Related]
5. Identification of protein quality control regulators using a Drosophila model of TPI deficiency.
Hrizo SL; Eicher SL; Myers TD; McGrath I; Wodrich APK; Venkatesh H; Manjooran D; Swoger S; Gagnon K; Bruskin M; Lebedev MV; Zheng S; Vitantonio A; Kim S; Lamb ZJ; Vogt A; Ruzhnikov MRZ; Palladino MJ
Neurobiol Dis; 2021 May; 152():105299. PubMed ID: 33600953
[TBL] [Abstract][Full Text] [Related]
6. Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency.
Hrizo SL; Fisher IJ; Long DR; Hutton JA; Liu Z; Palladino MJ
Neurobiol Dis; 2013 Jun; 54():289-96. PubMed ID: 23318931
[TBL] [Abstract][Full Text] [Related]
7. Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Roland BP; Amrich CG; Kammerer CJ; Stuchul KA; Larsen SB; Rode S; Aslam AA; Heroux A; Wetzel R; VanDemark AP; Palladino MJ
Biochim Biophys Acta; 2015 Jan; 1852(1):61-9. PubMed ID: 25463631
[TBL] [Abstract][Full Text] [Related]
8. Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes.
Ralser M; Heeren G; Breitenbach M; Lehrach H; Krobitsch S
PLoS One; 2006 Dec; 1(1):e30. PubMed ID: 17183658
[TBL] [Abstract][Full Text] [Related]
9. Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Roland BP; Richards KR; Hrizo SL; Eicher S; Barile ZJ; Chang TC; Savon G; Bianchi P; Fermo E; Ricerca BM; Tortorolo L; Vockley J; VanDemark AP; Palladino MJ
Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2257-2266. PubMed ID: 31075491
[TBL] [Abstract][Full Text] [Related]
10. Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.
Roland BP; Zeccola AM; Larsen SB; Amrich CG; Talsma AD; Stuchul KA; Heroux A; Levitan ES; VanDemark AP; Palladino MJ
PLoS Genet; 2016 Mar; 12(3):e1005941. PubMed ID: 27031109
[TBL] [Abstract][Full Text] [Related]
11. Triosephosphate isomerase deficiency: facts and doubts.
Orosz F; Oláh J; Ovádi J
IUBMB Life; 2006 Dec; 58(12):703-15. PubMed ID: 17424909
[TBL] [Abstract][Full Text] [Related]
12. Metabolic correction of triose phosphate isomerase deficiency in vitro by complementation.
Ationu A; Humphries A; Bellingham A; Layton M
Biochem Biophys Res Commun; 1997 Mar; 232(2):528-31. PubMed ID: 9125215
[TBL] [Abstract][Full Text] [Related]
13. A High-Content Screening Assay for Small Molecules That Stabilize Mutant Triose Phosphate Isomerase (TPI) as Treatments for TPI Deficiency.
Vogt A; Eicher SL; Myers TD; Hrizo SL; Vollmer LL; Meyer EM; Palladino MJ
SLAS Discov; 2021 Sep; 26(8):1029-1039. PubMed ID: 34167376
[TBL] [Abstract][Full Text] [Related]
14. Triosephosphate isomerase deficiency: consequences of an inherited mutation at mRNA, protein and metabolic levels.
Oláh J; Orosz F; Puskás LG; Hackler L; Horányi M; Polgár L; Hollán S; Ovádi J
Biochem J; 2005 Dec; 392(Pt 3):675-83. PubMed ID: 16086671
[TBL] [Abstract][Full Text] [Related]
15. Newly discovered roles of triosephosphate isomerase including functions within the nucleus.
Myers TD; Palladino MJ
Mol Med; 2023 Jan; 29(1):18. PubMed ID: 36721084
[TBL] [Abstract][Full Text] [Related]
16. Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
Segal J; Mülleder M; Krüger A; Adler T; Scholze-Wittler M; Becker L; Calzada-Wack J; Garrett L; Hölter SM; Rathkolb B; Rozman J; Racz I; Fischer R; Busch DH; Neff F; Klingenspor M; Klopstock T; Grüning NM; Michel S; Lukaszewska-McGreal B; Voigt I; Hartmann L; Timmermann B; Lehrach H; Wolf E; Wurst W; Gailus-Durner V; Fuchs H; H de Angelis M; Schrewe H; Yuneva M; Ralser M
J Inherit Metab Dis; 2019 Sep; 42(5):839-849. PubMed ID: 31111503
[TBL] [Abstract][Full Text] [Related]
17. Enhanced association of mutant triosephosphate isomerase to red cell membranes and to brain microtubules.
Orosz F; Wágner G; Liliom K; Kovács J; Baróti K; Horányi M; Farkas T; Hollán S; Ovádi J
Proc Natl Acad Sci U S A; 2000 Feb; 97(3):1026-31. PubMed ID: 10655478
[TBL] [Abstract][Full Text] [Related]
18. wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death.
Gnerer JP; Kreber RA; Ganetzky B
Proc Natl Acad Sci U S A; 2006 Oct; 103(41):14987-93. PubMed ID: 17008404
[TBL] [Abstract][Full Text] [Related]
19. In silico prediction of the effects of mutations in the human triose phosphate isomerase gene: Towards a predictive framework for TPI deficiency.
Oliver C; Timson DJ
Eur J Med Genet; 2017 Jun; 60(6):289-298. PubMed ID: 28341520
[TBL] [Abstract][Full Text] [Related]
20. Triosephosphate isomerase deficiency: new insights into an enigmatic disease.
Orosz F; Oláh J; Ovádi J
Biochim Biophys Acta; 2009 Dec; 1792(12):1168-74. PubMed ID: 19786097
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]