These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Filardo EJ; Quinn JA; Bland KI; Frackelton AR Mol Endocrinol; 2000 Oct; 14(10):1649-60. PubMed ID: 11043579 [TBL] [Abstract][Full Text] [Related]
3. G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells. Vivacqua A; Lappano R; De Marco P; Sisci D; Aquila S; De Amicis F; Fuqua SA; Andò S; Maggiolini M Mol Endocrinol; 2009 Nov; 23(11):1815-26. PubMed ID: 19749156 [TBL] [Abstract][Full Text] [Related]
4. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Filardo EJ; Quinn JA; Frackelton AR; Bland KI Mol Endocrinol; 2002 Jan; 16(1):70-84. PubMed ID: 11773440 [TBL] [Abstract][Full Text] [Related]
5. The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells. Maggiolini M; Vivacqua A; Fasanella G; Recchia AG; Sisci D; Pezzi V; Montanaro D; Musti AM; Picard D; Andò S J Biol Chem; 2004 Jun; 279(26):27008-16. PubMed ID: 15090535 [TBL] [Abstract][Full Text] [Related]
6. Bisphenol A at a low concentration boosts mouse spermatogonial cell proliferation by inducing the G protein-coupled receptor 30 expression. Sheng ZG; Huang W; Liu YX; Zhu BZ Toxicol Appl Pharmacol; 2013 Feb; 267(1):88-94. PubMed ID: 23274518 [TBL] [Abstract][Full Text] [Related]
7. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Albanito L; Madeo A; Lappano R; Vivacqua A; Rago V; Carpino A; Oprea TI; Prossnitz ER; Musti AM; Andò S; Maggiolini M Cancer Res; 2007 Feb; 67(4):1859-66. PubMed ID: 17308128 [TBL] [Abstract][Full Text] [Related]
8. The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. Ariazi EA; Brailoiu E; Yerrum S; Shupp HA; Slifker MJ; Cunliffe HE; Black MA; Donato AL; Arterburn JB; Oprea TI; Prossnitz ER; Dun NJ; Jordan VC Cancer Res; 2010 Feb; 70(3):1184-94. PubMed ID: 20086172 [TBL] [Abstract][Full Text] [Related]
9. MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells. Lappano R; Santolla MF; Pupo M; Sinicropi MS; Caruso A; Rosano C; Maggiolini M Breast Cancer Res; 2012 Jan; 14(1):R12. PubMed ID: 22251451 [TBL] [Abstract][Full Text] [Related]
10. Two novel GPER agonists induce gene expression changes and growth effects in cancer cells. Lappano R; Rosano C; Santolla MF; Pupo M; De Francesco EM; De Marco P; Ponassi M; Spallarossa A; Ranise A; Maggiolini M Curr Cancer Drug Targets; 2012 Jun; 12(5):531-42. PubMed ID: 22414008 [TBL] [Abstract][Full Text] [Related]
11. Inactivation of GPR30 reduces growth of triple-negative breast cancer cells: possible application in targeted therapy. Girgert R; Emons G; Gründker C Breast Cancer Res Treat; 2012 Jul; 134(1):199-205. PubMed ID: 22290080 [TBL] [Abstract][Full Text] [Related]
12. Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts. Madeo A; Maggiolini M Cancer Res; 2010 Jul; 70(14):6036-46. PubMed ID: 20551055 [TBL] [Abstract][Full Text] [Related]
13. Calycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling. Tian J; Wang Y; Zhang X; Ren Q; Li R; Huang Y; Lu H; Chen J J Exp Clin Cancer Res; 2017 Nov; 36(1):153. PubMed ID: 29096683 [TBL] [Abstract][Full Text] [Related]
14. The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo. Wei W; Chen ZJ; Zhang KS; Yang XL; Wu YM; Chen XH; Huang HB; Liu HL; Cai SH; Du J; Wang HS Cell Death Dis; 2014 Oct; 5(10):e1428. PubMed ID: 25275589 [TBL] [Abstract][Full Text] [Related]
15. Interaction Between CCL18 and GPR30 Differs from the Interaction Between Estradiol and GPR30. Schmidt-Wolf R; Zissel G Anticancer Res; 2020 Jun; 40(6):3097-3108. PubMed ID: 32487604 [TBL] [Abstract][Full Text] [Related]
16. Baicalein suppresses 17-β-estradiol-induced migration, adhesion and invasion of breast cancer cells via the G protein-coupled receptor 30 signaling pathway. Shang D; Li Z; Zhu Z; Chen H; Zhao L; Wang X; Chen Y Oncol Rep; 2015 Apr; 33(4):2077-85. PubMed ID: 25672442 [TBL] [Abstract][Full Text] [Related]
17. Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential significance for breast cancer. Filardo EJ J Steroid Biochem Mol Biol; 2002 Feb; 80(2):231-8. PubMed ID: 11897506 [TBL] [Abstract][Full Text] [Related]
18. Inhibition of GPR30 by estriol prevents growth stimulation of triple-negative breast cancer cells by 17β-estradiol. Girgert R; Emons G; Gründker C BMC Cancer; 2014 Dec; 14():935. PubMed ID: 25496649 [TBL] [Abstract][Full Text] [Related]
19. GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells. Vivacqua A; Romeo E; De Marco P; De Francesco EM; Abonante S; Maggiolini M Breast Cancer Res Treat; 2012 Jun; 133(3):1025-35. PubMed ID: 22147081 [TBL] [Abstract][Full Text] [Related]
20. Nuclear estrogen receptor-mediated Notch signaling and GPR30-mediated PI3K/AKT signaling in the regulation of endometrial cancer cell proliferation. Wei Y; Zhang Z; Liao H; Wu L; Wu X; Zhou D; Xi X; Zhu Y; Feng Y Oncol Rep; 2012 Feb; 27(2):504-10. PubMed ID: 22075757 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]