123 related articles for article (PubMed ID: 18471074)
1. A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors.
Dai G; Haedo RJ; Warren VA; Ratliff KS; Bugianesi RM; Rush A; Williams ME; Herrington J; Smith MM; McManus OB; Swensen AM
Assay Drug Dev Technol; 2008 Apr; 6(2):195-212. PubMed ID: 18471074
[TBL] [Abstract][Full Text] [Related]
2. Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels.
Swensen AM; Herrington J; Bugianesi RM; Dai G; Haedo RJ; Ratliff KS; Smith MM; Warren VA; Arneric SP; Eduljee C; Parker D; Snutch TP; Hoyt SB; London C; Duffy JL; Kaczorowski GJ; McManus OB
Mol Pharmacol; 2012 Mar; 81(3):488-97. PubMed ID: 22188924
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the triazine, T4, a representative from a novel series of CaV2 inhibitors with strong state-dependence, poor use-dependence, and distinctively fast kinetics.
Swensen AM; Niforatos W; Lee CH; Jarvis MF; McGaraughty S
Eur J Pharmacol; 2014 Dec; 745():234-42. PubMed ID: 25446431
[TBL] [Abstract][Full Text] [Related]
4. Validation of high throughput screening assays against three subtypes of Ca(v)3 T-type channels using molecular and pharmacologic approaches.
Xie X; Van Deusen AL; Vitko I; Babu DA; Davies LA; Huynh N; Cheng H; Yang N; Barrett PQ; Perez-Reyes E
Assay Drug Dev Technol; 2007 Apr; 5(2):191-203. PubMed ID: 17477828
[TBL] [Abstract][Full Text] [Related]
5. State-dependent inhibition of L-type calcium channels: cell-based assay in high-throughput format.
Xia M; Imredy JP; Koblan KS; Bennett P; Connolly TM
Anal Biochem; 2004 Apr; 327(1):74-81. PubMed ID: 15033513
[TBL] [Abstract][Full Text] [Related]
6. Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
Abbadie C; McManus OB; Sun SY; Bugianesi RM; Dai G; Haedo RJ; Herrington JB; Kaczorowski GJ; Smith MM; Swensen AM; Warren VA; Williams B; Arneric SP; Eduljee C; Snutch TP; Tringham EW; Jochnowitz N; Liang A; Euan MacIntyre D; McGowan E; Mistry S; White VV; Hoyt SB; London C; Lyons KA; Bunting PB; Volksdorf S; Duffy JL
J Pharmacol Exp Ther; 2010 Aug; 334(2):545-55. PubMed ID: 20439438
[TBL] [Abstract][Full Text] [Related]
7. Identification of State-Dependent Blockers for Voltage-Gated Calcium Channels Using a FLIPR-Based Assay.
di Silvio A; Rolland J; Stucchi M
Methods Mol Biol; 2016; 1439():197-206. PubMed ID: 27316997
[TBL] [Abstract][Full Text] [Related]
8. An automated electrophysiological assay for differentiating Ca(v)2.2 inhibitors based on state dependence and kinetics.
Swensen AM; Niforatos W; Vortherms TA; Perner RJ; Li T; Schrimpf MR; Scott VE; Lee L; Jarvis MF; McGaraughty S
Assay Drug Dev Technol; 2012 Dec; 10(6):542-50. PubMed ID: 22428804
[TBL] [Abstract][Full Text] [Related]
9. A fluorescence-based high-throughput screening assay for the identification of T-type calcium channel blockers.
Belardetti F; Tringham E; Eduljee C; Jiang X; Dong H; Hendricson A; Shimizu Y; Janke DL; Parker D; Mezeyova J; Khawaja A; Pajouhesh H; Fraser RA; Arneric SP; Snutch TP
Assay Drug Dev Technol; 2009 Jun; 7(3):266-80. PubMed ID: 19530894
[TBL] [Abstract][Full Text] [Related]
10. An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists.
Finley MF; Lubin ML; Neeper MP; Beck E; Liu Y; Flores CM; Qin N
Assay Drug Dev Technol; 2010 Dec; 8(6):685-94. PubMed ID: 21050074
[TBL] [Abstract][Full Text] [Related]
11. ZC88, a novel N-type calcium channel blocker from 4-amino-piperidine derivatives state-dependent inhibits Cav2.2 calcium channels.
Zhang S; Yang L; Zhang K; Liu X; Dai W; Zhang C; Yong Z; Li J; Zheng J
Brain Res; 2015 Apr; 1605():12-21. PubMed ID: 25681549
[TBL] [Abstract][Full Text] [Related]
12. Roscovitine differentially affects CaV2 and Kv channels by binding to the open state.
Buraei Z; Schofield G; Elmslie KS
Neuropharmacology; 2007 Mar; 52(3):883-94. PubMed ID: 17125805
[TBL] [Abstract][Full Text] [Related]
13. Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays.
Kuryshev YA; Brown AM; Duzic E; Kirsch GE
Assay Drug Dev Technol; 2014 Mar; 12(2):110-9. PubMed ID: 24579774
[TBL] [Abstract][Full Text] [Related]
14. Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis.
Rahman W; Patel R; Dickenson AH
Neuroscience; 2015 Oct; 305():76-85. PubMed ID: 26247695
[TBL] [Abstract][Full Text] [Related]
15. The biochemical activation of T-type Ca2+ channels in HEK293 cells stably expressing alpha1G and Kir2.1 subunits.
Kim T; Choi J; Kim S; Kwon O; Nah SY; Han YS; Rhim H
Biochem Biophys Res Commun; 2004 Nov; 324(1):401-8. PubMed ID: 15465033
[TBL] [Abstract][Full Text] [Related]
16. Voltage-dependent sodium channels and calcium-activated potassium channels in human odontoblasts in vitro.
Ichikawa H; Kim HJ; Shuprisha A; Shikano T; Tsumura M; Shibukawa Y; Tazaki M
J Endod; 2012 Oct; 38(10):1355-62. PubMed ID: 22980177
[TBL] [Abstract][Full Text] [Related]
17. Altered synaptic transmission at olfactory and vomeronasal nerve terminals in mice lacking N-type calcium channel Cav2.2.
Weiss J; Pyrski M; Weissgerber P; Zufall F
Eur J Neurosci; 2014 Nov; 40(10):3422-35. PubMed ID: 25195871
[TBL] [Abstract][Full Text] [Related]
18. Acetylcholine release at neuromuscular junctions of adult tottering mice is controlled by N-(cav2.2) and R-type (cav2.3) but not L-type (cav1.2) Ca2+ channels.
Pardo NE; Hajela RK; Atchison WD
J Pharmacol Exp Ther; 2006 Dec; 319(3):1009-20. PubMed ID: 16982704
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological characterization of recombinant N-type calcium channel (Cav2.2) mediated calcium mobilization using FLIPR.
Benjamin ER; Pruthi F; Olanrewaju S; Shan S; Hanway D; Liu X; Cerne R; Lavery D; Valenzano KJ; Woodward RM; Ilyin VI
Biochem Pharmacol; 2006 Sep; 72(6):770-82. PubMed ID: 16844100
[TBL] [Abstract][Full Text] [Related]
20. A reconfiguration of CaV2 Ca2+ channel current and its dopaminergic D2 modulation in developing neostriatal neurons.
Salgado H; Tecuapetla F; Perez-Rosello T; Perez-Burgos A; Perez-Garci E; Galarraga E; Bargas J
J Neurophysiol; 2005 Dec; 94(6):3771-87. PubMed ID: 16120665
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
