BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 18474592)

  • 1. Reactive nitrogen species is required for the activation of the AMP-activated protein kinase by statin in vivo.
    Choi HC; Song P; Xie Z; Wu Y; Xu J; Zhang M; Dong Y; Wang S; Lau K; Zou MH
    J Biol Chem; 2008 Jul; 283(29):20186-97. PubMed ID: 18474592
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.
    Xie Z; Dong Y; Scholz R; Neumann D; Zou MH
    Circulation; 2008 Feb; 117(7):952-62. PubMed ID: 18250273
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.
    Xie Z; Dong Y; Zhang M; Cui MZ; Cohen RA; Riek U; Neumann D; Schlattner U; Zou MH
    J Biol Chem; 2006 Mar; 281(10):6366-75. PubMed ID: 16407220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta.
    Kou R; Sartoretto J; Michel T
    J Biol Chem; 2009 May; 284(22):14734-43. PubMed ID: 19332549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species.
    Zou MH; Kirkpatrick SS; Davis BJ; Nelson JS; Wiles WG; Schlattner U; Neumann D; Brownlee M; Freeman MB; Goldman MH
    J Biol Chem; 2004 Oct; 279(42):43940-51. PubMed ID: 15265871
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.
    Shen QW; Zhu MJ; Tong J; Ren J; Du M
    Am J Physiol Cell Physiol; 2007 Oct; 293(4):C1395-403. PubMed ID: 17687000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase.
    Wu Y; Song P; Xu J; Zhang M; Zou MH
    J Biol Chem; 2007 Mar; 282(13):9777-9788. PubMed ID: 17255104
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta.
    Stahmann N; Woods A; Carling D; Heller R
    Mol Cell Biol; 2006 Aug; 26(16):5933-45. PubMed ID: 16880506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of serine 399 in LKB1 protein short form by protein kinase Cζ is required for its nucleocytoplasmic transport and consequent AMP-activated protein kinase (AMPK) activation.
    Zhu H; Moriasi CM; Zhang M; Zhao Y; Zou MH
    J Biol Chem; 2013 Jun; 288(23):16495-16505. PubMed ID: 23612973
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Statins activate AMP-activated protein kinase in vitro and in vivo.
    Sun W; Lee TS; Zhu M; Gu C; Wang Y; Zhu Y; Shyy JY
    Circulation; 2006 Dec; 114(24):2655-62. PubMed ID: 17116771
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway.
    Levine YC; Li GK; Michel T
    J Biol Chem; 2007 Jul; 282(28):20351-64. PubMed ID: 17519230
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis.
    Xie Z; Dong Y; Zhang J; Scholz R; Neumann D; Zou MH
    Mol Cell Biol; 2009 Jul; 29(13):3582-96. PubMed ID: 19414597
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.
    Zou MH; Hou XY; Shi CM; Kirkpatick S; Liu F; Goldman MH; Cohen RA
    J Biol Chem; 2003 Sep; 278(36):34003-10. PubMed ID: 12824177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.
    Zou MH; Hou XY; Shi CM; Nagata D; Walsh K; Cohen RA
    J Biol Chem; 2002 Sep; 277(36):32552-7. PubMed ID: 12107173
    [TBL] [Abstract][Full Text] [Related]  

  • 15. eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1.
    Thors B; Halldórsson H; Thorgeirsson G
    Biochim Biophys Acta; 2011 Feb; 1813(2):322-31. PubMed ID: 21145922
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase.
    Stahmann N; Woods A; Spengler K; Heslegrave A; Bauer R; Krause S; Viollet B; Carling D; Heller R
    J Biol Chem; 2010 Apr; 285(14):10638-52. PubMed ID: 20129920
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.
    Davis BJ; Xie Z; Viollet B; Zou MH
    Diabetes; 2006 Feb; 55(2):496-505. PubMed ID: 16443786
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy.
    Lim JH; Kim HW; Kim MY; Kim TW; Kim EN; Kim Y; Chung S; Kim YS; Choi BS; Kim YS; Chang YS; Kim HW; Park CW
    Cell Death Dis; 2018 Feb; 9(3):270. PubMed ID: 29449563
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Redox regulation of the AMP-activated protein kinase.
    Han Y; Wang Q; Song P; Zhu Y; Zou MH
    PLoS One; 2010 Nov; 5(11):e15420. PubMed ID: 21079763
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633.
    Chen Z; Peng IC; Sun W; Su MI; Hsu PH; Fu Y; Zhu Y; DeFea K; Pan S; Tsai MD; Shyy JY
    Circ Res; 2009 Feb; 104(4):496-505. PubMed ID: 19131647
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.