BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

559 related articles for article (PubMed ID: 18474681)

  • 1. Regio- and stereospecific N-glucuronidation of medetomidine: the differences between UDP glucuronosyltransferase (UGT) 1A4 and UGT2B10 account for the complex kinetics of human liver microsomes.
    Kaivosaari S; Toivonen P; Aitio O; Sipilä J; Koskinen M; Salonen JS; Finel M
    Drug Metab Dispos; 2008 Aug; 36(8):1529-37. PubMed ID: 18474681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10.
    Kaivosaari S; Toivonen P; Hesse LM; Koskinen M; Court MH; Finel M
    Mol Pharmacol; 2007 Sep; 72(3):761-8. PubMed ID: 17576790
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H; Kume T
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [TBL] [Abstract][Full Text] [Related]  

  • 4. UDP-glucuronosyltransferase 1A6 is the major isozyme responsible for protocatechuic aldehyde glucuronidation in human liver microsomes.
    Liu HX; Liu Y; Zhang JW; Li W; Liu HT; Yang L
    Drug Metab Dispos; 2008 Aug; 36(8):1562-9. PubMed ID: 18474676
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N-glucuronidation of the platelet-derived growth factor receptor tyrosine kinase inhibitor 6,7-(dimethoxy-2,4-dihydroindeno[1,2-C]pyrazol-3-yl)-(3-fluoro-phenyl)-amine by human UDP-glucuronosyltransferases.
    Yan Z; Caldwell GW; Gauthier D; Leo GC; Mei J; Ho CY; Jones WJ; Masucci JA; Tuman RW; Galemmo RA; Johnson DL
    Drug Metab Dispos; 2006 May; 34(5):748-55. PubMed ID: 16455802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H; Nakajima M; Katoh M; Kanoh A; Tamura O; Ishibashi H; Yokoi T
    Drug Metab Dispos; 2005 Jan; 33(1):23-30. PubMed ID: 15470160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog, and human liver microsomes.
    Kaivosaari S; Salonen JS; Taskinen J
    Drug Metab Dispos; 2002 Mar; 30(3):295-300. PubMed ID: 11854148
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.
    Chen M; LeDuc B; Kerr S; Howe D; Williams DA
    Drug Metab Dispos; 2010 Mar; 38(3):368-75. PubMed ID: 20008037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.
    Hanioka N; Naito T; Narimatsu S
    Chemosphere; 2008 Dec; 74(1):33-6. PubMed ID: 18990428
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases.
    Yu L; Lu S; Lin Y; Zeng S
    Biochem Pharmacol; 2007 Jun; 73(11):1842-51. PubMed ID: 17359941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics.
    Wen Z; Tallman MN; Ali SY; Smith PC
    Drug Metab Dispos; 2007 Mar; 35(3):371-80. PubMed ID: 17151191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
    Innocenti F; Iyer L; RamĂ­rez J; Green MD; Ratain MJ
    Drug Metab Dispos; 2001 May; 29(5):686-92. PubMed ID: 11302935
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.
    Tong Z; Li H; Goljer I; McConnell O; Chandrasekaran A
    Drug Metab Dispos; 2007 Dec; 35(12):2203-10. PubMed ID: 17875670
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucuronidation of anti-HIV drug candidate bevirimat: identification of human UDP-glucuronosyltransferases and species differences.
    Wen Z; Martin DE; Bullock P; Lee KH; Smith PC
    Drug Metab Dispos; 2007 Mar; 35(3):440-8. PubMed ID: 17151190
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.
    Li T; Zheng Y; Fu F; Ji H; Chen X; Zhao Y; Zhao D; Li N; Zhang L
    Xenobiotica; 2011 Jul; 41(7):530-7. PubMed ID: 21524190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative N-glucuronidation kinetics of ketotifen and amitriptyline by expressed human UDP-glucuronosyltransferases and liver microsomes.
    Breyer-Pfaff U; Mey U; Green MD; Tephly TR
    Drug Metab Dispos; 2000 Aug; 28(8):869-72. PubMed ID: 10901693
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 4-Aminobiphenyl N-glucuronidation by liver microsomes: optimization of the reaction conditions and characterization of the UDP-glucuronosyltransferase isoforms.
    Al-Zoughool M; Talaska G
    J Appl Toxicol; 2006; 26(6):524-32. PubMed ID: 17080401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]methyl]quinoline N-glucuronidation by in vitro and in vivo approaches.
    Stevens JC; Fayer JL; Cassidy KC
    Drug Metab Dispos; 2001 Mar; 29(3):289-95. PubMed ID: 11181497
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-performance liquid chromatographic method combining radiochemical and ultraviolet detection for determination of low activities of uridine 5'-diphosphate-glucuronosyltransferase.
    Kaivosaari S; Salonen JS; Mortensen J; Taskinen J
    Anal Biochem; 2001 May; 292(2):178-87. PubMed ID: 11355849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.