216 related articles for article (PubMed ID: 18474869)
21. Interception of benzo[a]pyrene-7,8-dione by UDP glucuronosyltransferases (UGTs) in human lung cells.
Zhang L; Huang M; Blair IA; Penning TM
Chem Res Toxicol; 2013 Oct; 26(10):1570-8. PubMed ID: 24047243
[TBL] [Abstract][Full Text] [Related]
22. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
Shimada T; Martin MV; Pruess-Schwartz D; Marnett LJ; Guengerich FP
Cancer Res; 1989 Nov; 49(22):6304-12. PubMed ID: 2509067
[TBL] [Abstract][Full Text] [Related]
23. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
Jiang H; Shen YM; Quinn AM; Penning TM
Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
[TBL] [Abstract][Full Text] [Related]
24. Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction.
Jiang H; Vudathala DK; Blair IA; Penning TM
Chem Res Toxicol; 2006 Jan; 19(1):68-78. PubMed ID: 16411658
[TBL] [Abstract][Full Text] [Related]
25. Quantitation of benzo[a]pyrene metabolic profiles in human bronchoalveolar (H358) cells by stable isotope dilution liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
Lu D; Harvey RG; Blair IA; Penning TM
Chem Res Toxicol; 2011 Nov; 24(11):1905-14. PubMed ID: 21962213
[TBL] [Abstract][Full Text] [Related]
26. Identification and characterization of novel stable deoxyguanosine and deoxyadenosine adducts of benzo[a]pyrene-7,8-quinone from reactions at physiological pH.
Balu N; Padgett WT; Lambert GR; Swank AE; Richard AM; Nesnow S
Chem Res Toxicol; 2004 Jun; 17(6):827-38. PubMed ID: 15206904
[TBL] [Abstract][Full Text] [Related]
27. Stable expression of rat dihydrodiol dehydrogenase (AKR1C9) in human breast MCF-7 cells results in the formation of PAH-o-quinones and enzyme mediated cell death.
Tsuruda L; Hou Yt ; Penning TM
Chem Res Toxicol; 2001 Jul; 14(7):856-62. PubMed ID: 11453732
[TBL] [Abstract][Full Text] [Related]
28. Disposition and biological activity of benzo[a]pyrene-7,8-dione. A genotoxic metabolite generated by dihydrodiol dehydrogenase.
Flowers L; Bleczinski WF; Burczynski ME; Harvey RG; Penning TM
Biochemistry; 1996 Oct; 35(42):13664-72. PubMed ID: 8885846
[TBL] [Abstract][Full Text] [Related]
29. Metabolic activation of polycyclic aromatic hydrocarbon trans-dihydrodiols by ubiquitously expressed aldehyde reductase (AKR1A1).
Palackal NT; Burczynski ME; Harvey RG; Penning TM
Chem Biol Interact; 2001 Jan; 130-132(1-3):815-24. PubMed ID: 11306097
[TBL] [Abstract][Full Text] [Related]
30. Oxidative DNA damage induced by benz[a]anthracene dihydrodiols in the presence of dihydrodiol dehydrogenase.
Seike K; Murata M; Hirakawa K; Deyashiki Y; Kawanishi S
Chem Res Toxicol; 2004 Nov; 17(11):1445-51. PubMed ID: 15540942
[TBL] [Abstract][Full Text] [Related]
31. Detoxication of benzo[a]pyrene-7,8-dione by sulfotransferases (SULTs) in human lung cells.
Zhang L; Huang M; Blair IA; Penning TM
J Biol Chem; 2012 Aug; 287(35):29909-20. PubMed ID: 22782890
[TBL] [Abstract][Full Text] [Related]
32. Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[a]pyrene with benzo[a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts.
Nesnow S; Davis C; Nelson GB; Lambert G; Padgett W; Pimentel M; Tennant AH; Kligerman AD; Ross JA
Mutat Res; 2002 Nov; 521(1-2):91-102. PubMed ID: 12438007
[TBL] [Abstract][Full Text] [Related]
33. Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry.
Ruan Q; Kim HY; Jiang H; Penning TM; Harvey RG; Blair IA
Rapid Commun Mass Spectrom; 2006; 20(8):1369-80. PubMed ID: 16557497
[TBL] [Abstract][Full Text] [Related]
34. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
[TBL] [Abstract][Full Text] [Related]
35. Detoxication of structurally diverse polycyclic aromatic hydrocarbon (PAH) o-quinones by human recombinant catechol-O-methyltransferase (COMT) via O-methylation of PAH catechols.
Zhang L; Jin Y; Chen M; Huang M; Harvey RG; Blair IA; Penning TM
J Biol Chem; 2011 Jul; 286(29):25644-54. PubMed ID: 21622560
[TBL] [Abstract][Full Text] [Related]
36. Benzo[a]pyrene-7,8-dihydrodiol promotes checkpoint activation and G2/M arrest in human bronchoalveolar carcinoma H358 cells.
Caino MC; Oliva JL; Jiang H; Penning TM; Kazanietz MG
Mol Pharmacol; 2007 Mar; 71(3):744-50. PubMed ID: 17114299
[TBL] [Abstract][Full Text] [Related]
37. Metabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometry.
Jiang H; Gelhaus SL; Mangal D; Harvey RG; Blair IA; Penning TM
Chem Res Toxicol; 2007 Sep; 20(9):1331-41. PubMed ID: 17702526
[TBL] [Abstract][Full Text] [Related]
38. Contribution of dihydrodiol dehydrogenase to the metabolism of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene in fortified rat liver subcellular fractions.
Shou M; Harvey RG; Penning TM
Carcinogenesis; 1992 Sep; 13(9):1575-82. PubMed ID: 1394842
[TBL] [Abstract][Full Text] [Related]
39. Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor.
Burczynski ME; Penning TM
Cancer Res; 2000 Feb; 60(4):908-15. PubMed ID: 10706104
[TBL] [Abstract][Full Text] [Related]
40. Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinone depurinating N7-guanine adducts.
McCoull KD; Rindgen D; Blair IA; Penning TM
Chem Res Toxicol; 1999 Mar; 12(3):237-46. PubMed ID: 10077486
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]