BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 18474869)

  • 21. Interception of benzo[a]pyrene-7,8-dione by UDP glucuronosyltransferases (UGTs) in human lung cells.
    Zhang L; Huang M; Blair IA; Penning TM
    Chem Res Toxicol; 2013 Oct; 26(10):1570-8. PubMed ID: 24047243
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
    Shimada T; Martin MV; Pruess-Schwartz D; Marnett LJ; Guengerich FP
    Cancer Res; 1989 Nov; 49(22):6304-12. PubMed ID: 2509067
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
    Jiang H; Shen YM; Quinn AM; Penning TM
    Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction.
    Jiang H; Vudathala DK; Blair IA; Penning TM
    Chem Res Toxicol; 2006 Jan; 19(1):68-78. PubMed ID: 16411658
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Quantitation of benzo[a]pyrene metabolic profiles in human bronchoalveolar (H358) cells by stable isotope dilution liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
    Lu D; Harvey RG; Blair IA; Penning TM
    Chem Res Toxicol; 2011 Nov; 24(11):1905-14. PubMed ID: 21962213
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification and characterization of novel stable deoxyguanosine and deoxyadenosine adducts of benzo[a]pyrene-7,8-quinone from reactions at physiological pH.
    Balu N; Padgett WT; Lambert GR; Swank AE; Richard AM; Nesnow S
    Chem Res Toxicol; 2004 Jun; 17(6):827-38. PubMed ID: 15206904
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Stable expression of rat dihydrodiol dehydrogenase (AKR1C9) in human breast MCF-7 cells results in the formation of PAH-o-quinones and enzyme mediated cell death.
    Tsuruda L; Hou Yt ; Penning TM
    Chem Res Toxicol; 2001 Jul; 14(7):856-62. PubMed ID: 11453732
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Disposition and biological activity of benzo[a]pyrene-7,8-dione. A genotoxic metabolite generated by dihydrodiol dehydrogenase.
    Flowers L; Bleczinski WF; Burczynski ME; Harvey RG; Penning TM
    Biochemistry; 1996 Oct; 35(42):13664-72. PubMed ID: 8885846
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Metabolic activation of polycyclic aromatic hydrocarbon trans-dihydrodiols by ubiquitously expressed aldehyde reductase (AKR1A1).
    Palackal NT; Burczynski ME; Harvey RG; Penning TM
    Chem Biol Interact; 2001 Jan; 130-132(1-3):815-24. PubMed ID: 11306097
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Oxidative DNA damage induced by benz[a]anthracene dihydrodiols in the presence of dihydrodiol dehydrogenase.
    Seike K; Murata M; Hirakawa K; Deyashiki Y; Kawanishi S
    Chem Res Toxicol; 2004 Nov; 17(11):1445-51. PubMed ID: 15540942
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Detoxication of benzo[a]pyrene-7,8-dione by sulfotransferases (SULTs) in human lung cells.
    Zhang L; Huang M; Blair IA; Penning TM
    J Biol Chem; 2012 Aug; 287(35):29909-20. PubMed ID: 22782890
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[a]pyrene with benzo[a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts.
    Nesnow S; Davis C; Nelson GB; Lambert G; Padgett W; Pimentel M; Tennant AH; Kligerman AD; Ross JA
    Mutat Res; 2002 Nov; 521(1-2):91-102. PubMed ID: 12438007
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry.
    Ruan Q; Kim HY; Jiang H; Penning TM; Harvey RG; Blair IA
    Rapid Commun Mass Spectrom; 2006; 20(8):1369-80. PubMed ID: 16557497
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
    Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Detoxication of structurally diverse polycyclic aromatic hydrocarbon (PAH) o-quinones by human recombinant catechol-O-methyltransferase (COMT) via O-methylation of PAH catechols.
    Zhang L; Jin Y; Chen M; Huang M; Harvey RG; Blair IA; Penning TM
    J Biol Chem; 2011 Jul; 286(29):25644-54. PubMed ID: 21622560
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Benzo[a]pyrene-7,8-dihydrodiol promotes checkpoint activation and G2/M arrest in human bronchoalveolar carcinoma H358 cells.
    Caino MC; Oliva JL; Jiang H; Penning TM; Kazanietz MG
    Mol Pharmacol; 2007 Mar; 71(3):744-50. PubMed ID: 17114299
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Metabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometry.
    Jiang H; Gelhaus SL; Mangal D; Harvey RG; Blair IA; Penning TM
    Chem Res Toxicol; 2007 Sep; 20(9):1331-41. PubMed ID: 17702526
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Contribution of dihydrodiol dehydrogenase to the metabolism of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene in fortified rat liver subcellular fractions.
    Shou M; Harvey RG; Penning TM
    Carcinogenesis; 1992 Sep; 13(9):1575-82. PubMed ID: 1394842
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor.
    Burczynski ME; Penning TM
    Cancer Res; 2000 Feb; 60(4):908-15. PubMed ID: 10706104
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinone depurinating N7-guanine adducts.
    McCoull KD; Rindgen D; Blair IA; Penning TM
    Chem Res Toxicol; 1999 Mar; 12(3):237-46. PubMed ID: 10077486
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.