These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 18475973)

  • 1. Cellular Uptake, DNA Binding and Apoptosis Induction of Cytotoxic Trans-[PtCl(2)(N,N-dimethylamine)(Isopropylamine)] in A2780cisR Ovarian Tumor Cells.
    Pérez JM; Montero EI; Quiroga AG; Fuertes MA; Alonso C; Navarro-Ranninger C
    Met Based Drugs; 2001; 8(1):29-37. PubMed ID: 18475973
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor and cellular pharmacological properties of a novel platinum(IV) complex: trans-[PtCl(2)(OH)(2)(dimethylamine) (isopropylamine)].
    Pérez JM; Kelland LR; Montero EI; Boxall FE; Fuertes MA; Alonso C; Navarro-Ranninger C
    Mol Pharmacol; 2003 Apr; 63(4):933-44. PubMed ID: 12644595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes.
    Montero EI; Pérez JM; Schwartz A; Fuertes MA; Malinge JM; Alonso C; Leng M; Navarro-Ranninger C
    Chembiochem; 2002 Jan; 3(1):61-7. PubMed ID: 17590955
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preparation and characterization of novel trans-[PtCl(2)(amine)(isopropylamine)] compounds: cytotoxic activity and apoptosis induction in ras-transformed cells.
    Montero EI; Díaz S; González-Vadillo AM; Pérez JM; Alonso C; Navarro-Ranninger C
    J Med Chem; 1999 Oct; 42(20):4264-8. PubMed ID: 10514297
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-Ray structure of cytotoxic trans-[PtCl(2)(dimethylamine)(isopropylamine)]: interstrand cross-link efficiency, DNA sequence specificity, and inhibition of the B-Z transition.
    Pérez JM; Montero EI; González AM; Solans X; Font-Bardia M; Fuertes MA; Alonso C; Navarro-Ranninger C
    J Med Chem; 2000 Jun; 43(12):2411-8. PubMed ID: 10882368
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis induction and inhibition of H-ras overexpression by novel trans-[PtCl2(isopropylamine)(amine')] complexes.
    Pérez JM; Montero EI; González AM; Alvarez-Valdés A; Alonso C; Navarro-Ranninger C
    J Inorg Biochem; 1999 Oct; 77(1-2):37-42. PubMed ID: 10626351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Theoretical analysis on the transition state of the anticancer drug trans-[PtCl2(isopropylamine)2] and its cis isomer binding to DNA purine bases.
    Zhou L
    J Phys Chem B; 2009 Feb; 113(7):2110-27. PubMed ID: 19173577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-protein cross-linking by trans-[PtCl(2)(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexes.
    Novakova O; Kasparkova J; Malina J; Natile G; Brabec V
    Nucleic Acids Res; 2003 Nov; 31(22):6450-60. PubMed ID: 14602903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cellular pharmacology of cis and trans pairs of platinum complexes in cisplatin-sensitive and -resistant human ovarian carcinoma cells.
    O'Neill CF; Hunakova L; Kelland LR
    Chem Biol Interact; 1999 Nov; 123(1):11-29. PubMed ID: 10597899
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution behaviour and biomolecular interactions of two cytotoxic trans-platinum(II) complexes bearing aliphatic amine ligands.
    Cubo L; Casini A; Gabbiani C; Mastrobuoni G; Messori L; Jiménez-Barbero J; Navarro-Ranninger C; Quiroga AG
    Chemistry; 2009 Sep; 15(36):9139-46. PubMed ID: 19655350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA and glutathione interactions in cell-free media of asymmetric platinum(II) complexes cis- and trans-[PtCl2(isopropylamine)(1-methylimidazole)]: relations to their different antitumor effects.
    Suchánková T; Vojtísková M; Reedijk J; Brabec V; Kaspárková J
    J Biol Inorg Chem; 2009 Jan; 14(1):75-87. PubMed ID: 18777181
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differences in the cellular response and signaling pathways of cisplatin and BBR3464 ([[trans-PtCl(NH3)(2)]2mu-(trans-Pt(NH3)(2)(H2N(CH2)(6)-NH2)2)]4+) influenced by copper homeostasis.
    Kabolizadeh P; Ryan J; Farrell N
    Biochem Pharmacol; 2007 May; 73(9):1270-9. PubMed ID: 17234160
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies.
    Najajreh Y; Khazanov E; Jawbry S; Ardeli-Tzaraf Y; Perez JM; Kasparkova J; Brabec V; Barenholz Y; Gibson D
    J Med Chem; 2006 Jul; 49(15):4665-73. PubMed ID: 16854072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of amine ligands on the aquation and cytotoxicity of trans-diamine platinum(II) anticancer complexes.
    Cubo L; Quiroga AG; Zhang J; Thomas DS; Carnero A; Navarro-Ranninger C; Berners-Price SJ
    Dalton Trans; 2009 May; (18):3457-66. PubMed ID: 19381408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines.
    Najajreh Y; Perez JM; Navarro-Ranninger C; Gibson D
    J Med Chem; 2002 Nov; 45(24):5189-95. PubMed ID: 12431046
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity.
    Cubo L; Hambley TW; Sanz Miguel PJ; Carnero A; Navarro-Ranninger C; Quiroga AG
    Dalton Trans; 2011 Jan; 40(2):344-7. PubMed ID: 20936210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies on synthesis, activity and binding with DNA of a new trinuclear platinum compound [{trans-PtCl(NH3)2}2{trans-Pt(thiazole)2}{H2N(CH2)(6NH2}2]Cl3(NO3).
    Al-Shuneigat J; Qing Y; Beale P; Fisher K; Huq F
    Med Chem; 2011 Jan; 7(1):1-8. PubMed ID: 21235513
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473.
    Holford J; Sharp SY; Murrer BA; Abrams M; Kelland LR
    Br J Cancer; 1998; 77(3):366-73. PubMed ID: 9472630
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studies of interaction of trichloro{eta2-cis-N,N-dimethyl-1-[6-(N',N'-dimethyl-ammoniummethyl)-cyclohex-3-ene-1-yl]-methylammonium}platinum(II) chloride with DNA: Effects on secondary and tertiary structures of DNA. Cytotoxic assays on human ovarian cancer cell lines, resistant and non-resistant to cisplatin.
    Gay M; Montaña AM; Moreno V; Prieto MJ; Pérez JM; Alonso C
    Bioorg Med Chem; 2006 Mar; 14(5):1565-72. PubMed ID: 16256352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
    Kasparkova J; Novakova O; Farrell N; Brabec V
    Biochemistry; 2003 Jan; 42(3):792-800. PubMed ID: 12534292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.