These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 18480410)

  • 1. Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease.
    Sun KH; de Pablo Y; Vincent F; Johnson EO; Chavers AK; Shah K
    Mol Biol Cell; 2008 Jul; 19(7):3052-69. PubMed ID: 18480410
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death.
    Chang KH; Vincent F; Shah K
    J Cell Sci; 2012 Nov; 125(Pt 21):5124-37. PubMed ID: 22899714
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cdk5-Foxo3 axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models.
    Shi C; Viccaro K; Lee HG; Shah K
    J Cell Sci; 2016 May; 129(9):1815-1830. PubMed ID: 28157684
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of Cdk5-mediated Drp1 phosphorylation in Aβ
    Guo MY; Shang L; Hu YY; Jiang LP; Wan YY; Zhou QQ; Zhang K; Liao HF; Yi JL; Han XJ
    J Cell Biochem; 2018 Jun; 119(6):4815-4825. PubMed ID: 29345339
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease.
    Crews L; Patrick C; Adame A; Rockenstein E; Masliah E
    Cell Death Dis; 2011 Feb; 2(2):e120. PubMed ID: 21368891
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies.
    Lopes JP; Oliveira CR; Agostinho P
    Cell Mol Neurobiol; 2007 Nov; 27(7):943-57. PubMed ID: 17965932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aβ-induced Golgi fragmentation in Alzheimer's disease enhances Aβ production.
    Joshi G; Chi Y; Huang Z; Wang Y
    Proc Natl Acad Sci U S A; 2014 Apr; 111(13):E1230-9. PubMed ID: 24639524
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death.
    Chang KH; Multani PS; Sun KH; Vincent F; de Pablo Y; Ghosh S; Gupta R; Lee HP; Lee HG; Smith MA; Shah K
    Mol Biol Cell; 2011 May; 22(9):1452-62. PubMed ID: 21389115
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Golgi fragmentation induced by overactivated cyclin-dependent kinase 5 is associated with isoflurane-induced neurotoxicity.
    Miao FF; Kong CC; Wu Y; Fan L; Wang TL
    Neuroreport; 2018 Mar; 29(4):241-246. PubMed ID: 29227343
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.
    Sadleir KR; Vassar R
    J Biol Chem; 2012 Mar; 287(10):7224-35. PubMed ID: 22223639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron.
    Chao AC; Chen CH; Wu MH; Hou BY; Yang DI
    Biochim Biophys Acta Mol Cell Res; 2020 Apr; 1867(4):118628. PubMed ID: 31884068
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis.
    Lowe M; Rabouille C; Nakamura N; Watson R; Jackman M; Jämsä E; Rahman D; Pappin DJ; Warren G
    Cell; 1998 Sep; 94(6):783-93. PubMed ID: 9753325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of mitofusin 2 links beta-amyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells.
    Park J; Choi H; Min JS; Kim B; Lee SR; Yun JW; Choi MS; Chang KT; Lee DS
    J Neurochem; 2015 Mar; 132(6):687-702. PubMed ID: 25359615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization.
    Lapresa R; Agulla J; Sánchez-Morán I; Zamarreño R; Prieto E; Bolaños JP; Almeida A
    Neuropharmacology; 2019 Mar; 146():19-27. PubMed ID: 30452955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons.
    Zheng YL; Kesavapany S; Gravell M; Hamilton RS; Schubert M; Amin N; Albers W; Grant P; Pant HC
    EMBO J; 2005 Jan; 24(1):209-20. PubMed ID: 15592431
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ginsenoside Rg1 reduces β‑amyloid levels by inhibiting CDΚ5‑induced PPARγ phosphorylation in a neuron model of Alzheimer's disease.
    Quan Q; Li X; Feng J; Hou J; Li M; Zhang B
    Mol Med Rep; 2020 Oct; 22(4):3277-3288. PubMed ID: 32945455
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tau secretion is correlated to an increase of Golgi dynamics.
    Mohamed NV; Desjardins A; Leclerc N
    PLoS One; 2017; 12(5):e0178288. PubMed ID: 28552936
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CDK5 Participates in Amyloid-β Production by Regulating PPARγ Phosphorylation in Primary Rat Hippocampal Neurons.
    Quan Q; Qian Y; Li X; Li M
    J Alzheimers Dis; 2019; 71(2):443-460. PubMed ID: 31403945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Golgin-84-associated Golgi fragmentation triggers tau hyperphosphorylation by activation of cyclin-dependent kinase-5 and extracellular signal-regulated kinase.
    Jiang Q; Wang L; Guan Y; Xu H; Niu Y; Han L; Wei YP; Lin L; Chu J; Wang Q; Yang Y; Pei L; Wang JZ; Tian Q
    Neurobiol Aging; 2014 Jun; 35(6):1352-63. PubMed ID: 24368089
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease.
    Sun KH; Lee HG; Smith MA; Shah K
    Mol Biol Cell; 2009 Nov; 20(21):4611-9. PubMed ID: 19776350
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.