BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 18481957)

  • 21. TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
    Loos RJ; Franks PW; Francis RW; Barroso I; Gribble FM; Savage DB; Ong KK; O'Rahilly S; Wareham NJ
    Diabetes; 2007 Jul; 56(7):1943-7. PubMed ID: 17416797
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.
    Kirchhoff K; Machicao F; Haupt A; Schäfer SA; Tschritter O; Staiger H; Stefan N; Häring HU; Fritsche A
    Diabetologia; 2008 Apr; 51(4):597-601. PubMed ID: 18264689
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice.
    Nguyen-Tu MS; Martinez-Sanchez A; Leclerc I; Rutter GA; da Silva Xavier G
    Diabetologia; 2021 Jan; 64(1):129-141. PubMed ID: 33068125
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Interactions between TCF7L2 genotype and growth hormone-induced changes in glucose homeostasis in small for gestational age children.
    de Kort SW; Mook-Kanamori DO; Jaddoe VW; Hokken-Koelega AC
    Clin Endocrinol (Oxf); 2010 Jan; 72(1):47-52. PubMed ID: 19473183
    [TBL] [Abstract][Full Text] [Related]  

  • 25. TCF7L2 is a master regulator of insulin production and processing.
    Zhou Y; Park SY; Su J; Bailey K; Ottosson-Laakso E; Shcherbina L; Oskolkov N; Zhang E; Thevenin T; Fadista J; Bennet H; Vikman P; Wierup N; Fex M; Rung J; Wollheim C; Nobrega M; Renström E; Groop L; Hansson O
    Hum Mol Genet; 2014 Dec; 23(24):6419-31. PubMed ID: 25015099
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolic, hormonal characteristics and genetic variants of TCF7L2 associated with development of gestational diabetes mellitus in Mexican women.
    Reyes-López R; Pérez-Luque E; Malacara JM
    Diabetes Metab Res Rev; 2014 Nov; 30(8):701-6. PubMed ID: 24639413
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Type 2 diabetes susceptibility gene TCF7L2 and its role in beta-cell function.
    Gloyn AL; Braun M; Rorsman P
    Diabetes; 2009 Apr; 58(4):800-2. PubMed ID: 19336690
    [No Abstract]   [Full Text] [Related]  

  • 28. Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner.
    Sakhneny L; Rachi E; Epshtein A; Guez HC; Wald-Altman S; Lisnyansky M; Khalifa-Malka L; Hazan A; Baer D; Priel A; Weil M; Landsman L
    Diabetes; 2018 Mar; 67(3):437-447. PubMed ID: 29246974
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance.
    Chang YC; Chiu YF; Ho LL; Ting CT; Shih KC; Curb JD; Chen YD; Li HY; Chuang LM
    J Mol Med (Berl); 2010 Feb; 88(2):183-92. PubMed ID: 19806338
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.
    Wang J; Kuusisto J; Vänttinen M; Kuulasmaa T; Lindström J; Tuomilehto J; Uusitupa M; Laakso M
    Diabetologia; 2007 Jun; 50(6):1192-200. PubMed ID: 17437080
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Prime suspect: the TCF7L2 gene and type 2 diabetes risk.
    Hattersley AT
    J Clin Invest; 2007 Aug; 117(8):2077-9. PubMed ID: 17671643
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells.
    Ye Y; Barghouth M; Luan C; Kazim A; Zhou Y; Eliasson L; Zhang E; Hansson O; Thevenin T; Renström E
    Mol Cell Endocrinol; 2020 Feb; 502():110673. PubMed ID: 31805307
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The enteroinsular axis may mediate the diabetogenic effects of TCF7L2 polymorphisms.
    Nauck MA; Meier JJ
    Diabetologia; 2007 Dec; 50(12):2413-6. PubMed ID: 17898988
    [No Abstract]   [Full Text] [Related]  

  • 34. Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
    Zhou Y; Zhang E; Berggreen C; Jing X; Osmark P; Lang S; Cilio CM; Göransson O; Groop L; Renström E; Hansson O
    Hum Mol Genet; 2012 Jan; 21(1):196-207. PubMed ID: 21965303
    [TBL] [Abstract][Full Text] [Related]  

  • 35. TCF7L2 genetic defect and type 2 diabetes.
    Cauchi S; Froguel P
    Curr Diab Rep; 2008 Apr; 8(2):149-55. PubMed ID: 18445358
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.
    Jin T; Liu L
    Mol Endocrinol; 2008 Nov; 22(11):2383-92. PubMed ID: 18599616
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A Reduced Incretin Effect Mediated by the rs7903146 Variant in the
    Galderisi A; Tricò D; Pierpont B; Shabanova V; Samuels S; Dalla Man C; Galuppo B; Santoro N; Caprio S
    Diabetes Care; 2020 Oct; 43(10):2553-2563. PubMed ID: 32788279
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice.
    da Silva Xavier G; Mondragon A; Mourougavelou V; Cruciani-Guglielmacci C; Denom J; Herrera PL; Magnan C; Rutter GA
    Diabetologia; 2017 Jun; 60(6):1043-1050. PubMed ID: 28343277
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A role for PAK1 mediated phosphorylation of β-catenin Ser552 in the regulation of insulin secretion.
    Sorrenson B; Dissanayake WC; Hu F; Lee KL; Shepherd PR
    Biochem J; 2021 Apr; 478(8):1605-1615. PubMed ID: 33605402
    [TBL] [Abstract][Full Text] [Related]  

  • 40. TCF7L2 splice variants have distinct effects on beta-cell turnover and function.
    Le Bacquer O; Shu L; Marchand M; Neve B; Paroni F; Kerr Conte J; Pattou F; Froguel P; Maedler K
    Hum Mol Genet; 2011 May; 20(10):1906-15. PubMed ID: 21357677
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.