112 related articles for article (PubMed ID: 18481983)
1. Disruption of ubiquitin-mediated processes in diseases of the brain and bone.
Layfield R; Searle MS
Biochem Soc Trans; 2008 Jun; 36(Pt 3):469-71. PubMed ID: 18481983
[TBL] [Abstract][Full Text] [Related]
2. p62 mutations, ubiquitin recognition and Paget's disease of bone.
Layfield R; Cavey JR; Najat D; Long J; Sheppard PW; Ralston SH; Searle MS
Biochem Soc Trans; 2006 Nov; 34(Pt 5):735-7. PubMed ID: 17052185
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone.
Najat D; Garner T; Hagen T; Shaw B; Sheppard PW; Falchetti A; Marini F; Brandi ML; Long JE; Cavey JR; Searle MS; Layfield R
J Bone Miner Res; 2009 Apr; 24(4):632-42. PubMed ID: 19049332
[TBL] [Abstract][Full Text] [Related]
4. A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype.
Rea SL; Walsh JP; Ward L; Yip K; Ward BK; Kent GN; Steer JH; Xu J; Ratajczak T
J Bone Miner Res; 2006 Jul; 21(7):1136-45. PubMed ID: 16813535
[TBL] [Abstract][Full Text] [Related]
5. SQSTM1 and Paget's disease of bone.
Layfield R; Hocking LJ
Calcif Tissue Int; 2004 Nov; 75(5):347-57. PubMed ID: 15365659
[TBL] [Abstract][Full Text] [Related]
6. p62 ubiquitin binding-associated domain mediated the receptor activator of nuclear factor-kappaB ligand-induced osteoclast formation: a new insight into the pathogenesis of Paget's disease of bone.
Yip KH; Feng H; Pavlos NJ; Zheng MH; Xu J
Am J Pathol; 2006 Aug; 169(2):503-14. PubMed ID: 16877352
[TBL] [Abstract][Full Text] [Related]
7. Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding.
Rea SL; Walsh JP; Ward L; Magno AL; Ward BK; Shaw B; Layfield R; Kent GN; Xu J; Ratajczak T
J Bone Miner Res; 2009 Jul; 24(7):1216-23. PubMed ID: 19257822
[TBL] [Abstract][Full Text] [Related]
8. Contribution of genetic factors to the pathogenesis of Paget's disease of bone and related disorders.
Lucas GJ; Daroszewska A; Ralston SH
J Bone Miner Res; 2006 Dec; 21 Suppl 2():P31-7. PubMed ID: 17229006
[TBL] [Abstract][Full Text] [Related]
9. NF-kappaB modulators in osteolytic bone diseases.
Xu J; Wu HF; Ang ES; Yip K; Woloszyn M; Zheng MH; Tan RX
Cytokine Growth Factor Rev; 2009 Feb; 20(1):7-17. PubMed ID: 19046922
[TBL] [Abstract][Full Text] [Related]
10. Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations.
Cavey JR; Ralston SH; Hocking LJ; Sheppard PW; Ciani B; Searle MS; Layfield R
J Bone Miner Res; 2005 Apr; 20(4):619-24. PubMed ID: 15765181
[TBL] [Abstract][Full Text] [Related]
11. New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Paget's disease of bone.
Rea SL; Walsh JP; Layfield R; Ratajczak T; Xu J
Endocr Rev; 2013 Aug; 34(4):501-24. PubMed ID: 23612225
[TBL] [Abstract][Full Text] [Related]
12. Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone.
Ciani B; Layfield R; Cavey JR; Sheppard PW; Searle MS
J Biol Chem; 2003 Sep; 278(39):37409-12. PubMed ID: 12857745
[TBL] [Abstract][Full Text] [Related]
13. Impact of p62/SQSTM1 UBA domain mutations linked to Paget's disease of bone on ubiquitin recognition.
Garner TP; Long J; Layfield R; Searle MS
Biochemistry; 2011 May; 50(21):4665-74. PubMed ID: 21517082
[TBL] [Abstract][Full Text] [Related]
14. Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function.
Goode A; Long JE; Shaw B; Ralston SH; Visconti MR; Gianfrancesco F; Esposito T; Gennari L; Merlotti D; Rendina D; Rea SL; Sultana M; Searle MS; Layfield R
Biochim Biophys Acta; 2014 Jul; 1842(7):992-1000. PubMed ID: 24642144
[TBL] [Abstract][Full Text] [Related]
15. Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences.
Hocking LJ; Lucas GJ; Daroszewska A; Cundy T; Nicholson GC; Donath J; Walsh JP; Finlayson C; Cavey JR; Ciani B; Sheppard PW; Searle MS; Layfield R; Ralston SH
J Bone Miner Res; 2004 Jul; 19(7):1122-7. PubMed ID: 15176995
[TBL] [Abstract][Full Text] [Related]
16. Dimerisation of the UBA domain of p62 inhibits ubiquitin binding and regulates NF-kappaB signalling.
Long J; Garner TP; Pandya MJ; Craven CJ; Chen P; Shaw B; Williamson MP; Layfield R; Searle MS
J Mol Biol; 2010 Feb; 396(1):178-94. PubMed ID: 19931284
[TBL] [Abstract][Full Text] [Related]
17. The aggravating role of the ubiquitin-proteasome system in neurodegeneration.
Ardley HC; Hung CC; Robinson PA
FEBS Lett; 2005 Jan; 579(3):571-6. PubMed ID: 15670810
[TBL] [Abstract][Full Text] [Related]
18. The molecular pathogenesis of Paget disease of bone.
Layfield R
Expert Rev Mol Med; 2007 Oct; 9(27):1-13. PubMed ID: 17903332
[TBL] [Abstract][Full Text] [Related]
19. Ubiquitin recognition by the ubiquitin-associated domain of p62 involves a novel conformational switch.
Long J; Gallagher TR; Cavey JR; Sheppard PW; Ralston SH; Layfield R; Searle MS
J Biol Chem; 2008 Feb; 283(9):5427-40. PubMed ID: 18083707
[TBL] [Abstract][Full Text] [Related]
20. The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts.
Chamoux E; Couture J; Bisson M; Morissette J; Brown JP; Roux S
Mol Endocrinol; 2009 Oct; 23(10):1668-80. PubMed ID: 19589897
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]