356 related articles for article (PubMed ID: 18483222)
1. PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling.
Chen R; Liu M; Li H; Xue Y; Ramey WN; He N; Ai N; Luo H; Zhu Y; Zhou N; Zhou Q
Genes Dev; 2008 May; 22(10):1356-68. PubMed ID: 18483222
[TBL] [Abstract][Full Text] [Related]
2. Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.
Bartholomeeusen K; Xiang Y; Fujinaga K; Peterlin BM
J Biol Chem; 2012 Oct; 287(43):36609-16. PubMed ID: 22952229
[TBL] [Abstract][Full Text] [Related]
3. Disrupting the Cdk9/Cyclin T1 heterodimer of 7SK snRNP for the Brd4 and AFF1/4 guided reconstitution of active P-TEFb.
Zhou K; Zhuang S; Liu F; Chen Y; Li Y; Wang S; Li Y; Wen H; Lin X; Wang J; Huang Y; He C; Xu N; Li Z; Xu L; Zhang Z; Chen LF; Chen R; Liu M
Nucleic Acids Res; 2022 Jan; 50(2):750-762. PubMed ID: 34935961
[TBL] [Abstract][Full Text] [Related]
4. Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.
Liu P; Xiang Y; Fujinaga K; Bartholomeeusen K; Nilson KA; Price DH; Peterlin BM
J Biol Chem; 2014 Apr; 289(14):9918-25. PubMed ID: 24515107
[TBL] [Abstract][Full Text] [Related]
5. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
Dow EC; Liu H; Rice AP
J Cell Physiol; 2010 Jul; 224(1):84-93. PubMed ID: 20201073
[TBL] [Abstract][Full Text] [Related]
6. PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.
Gudipaty SA; McNamara RP; Morton EL; D'Orso I
Mol Cell Biol; 2015 Nov; 35(22):3810-28. PubMed ID: 26324325
[TBL] [Abstract][Full Text] [Related]
7. Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.
Barboric M; Yik JH; Czudnochowski N; Yang Z; Chen R; Contreras X; Geyer M; Matija Peterlin B; Zhou Q
Nucleic Acids Res; 2007; 35(6):2003-12. PubMed ID: 17341462
[TBL] [Abstract][Full Text] [Related]
8. The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK.
Krueger BJ; Varzavand K; Cooper JJ; Price DH
PLoS One; 2010 Aug; 5(8):e12335. PubMed ID: 20808803
[TBL] [Abstract][Full Text] [Related]
9. Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation.
He N; Pezda AC; Zhou Q
Mol Cell Biol; 2006 Oct; 26(19):7068-76. PubMed ID: 16980611
[TBL] [Abstract][Full Text] [Related]
10. The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming.
Studniarek C; Tellier M; Martin PGP; Murphy S; Kiss T; Egloff S
Cell Rep; 2021 Apr; 35(2):108965. PubMed ID: 33852864
[TBL] [Abstract][Full Text] [Related]
11. HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription.
Contreras X; Barboric M; Lenasi T; Peterlin BM
PLoS Pathog; 2007 Oct; 3(10):1459-69. PubMed ID: 17937499
[TBL] [Abstract][Full Text] [Related]
12. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.
Mbonye UR; Gokulrangan G; Datt M; Dobrowolski C; Cooper M; Chance MR; Karn J
PLoS Pathog; 2013; 9(5):e1003338. PubMed ID: 23658523
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.
Mbonye UR; Wang B; Gokulrangan G; Chance MR; Karn J
Proteomics; 2015 Jun; 15(12):2078-86. PubMed ID: 25900325
[TBL] [Abstract][Full Text] [Related]
14. Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.
Mbonye U; Wang B; Gokulrangan G; Shi W; Yang S; Karn J
J Biol Chem; 2018 Jun; 293(26):10009-10025. PubMed ID: 29743242
[TBL] [Abstract][Full Text] [Related]
15. A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis.
He N; Jahchan NS; Hong E; Li Q; Bayfield MA; Maraia RJ; Luo K; Zhou Q
Mol Cell; 2008 Mar; 29(5):588-99. PubMed ID: 18249148
[TBL] [Abstract][Full Text] [Related]
16. Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.
Cho WK; Jang MK; Huang K; Pise-Masison CA; Brady JN
J Virol; 2010 Dec; 84(24):12801-9. PubMed ID: 20926576
[TBL] [Abstract][Full Text] [Related]
17. Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.
McNamara RP; McCann JL; Gudipaty SA; D'Orso I
Cell Rep; 2013 Dec; 5(5):1256-68. PubMed ID: 24316072
[TBL] [Abstract][Full Text] [Related]
18. The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.
Faust TB; Li Y; Bacon CW; Jang GM; Weiss A; Jayaraman B; Newton BW; Krogan NJ; D'Orso I; Frankel AD
Elife; 2018 May; 7():. PubMed ID: 29845934
[TBL] [Abstract][Full Text] [Related]
19. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.
Schröder S; Cho S; Zeng L; Zhang Q; Kaehlcke K; Mak L; Lau J; Bisgrove D; Schnölzer M; Verdin E; Zhou MM; Ott M
J Biol Chem; 2012 Jan; 287(2):1090-9. PubMed ID: 22084242
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA.
Yik JH; Chen R; Nishimura R; Jennings JL; Link AJ; Zhou Q
Mol Cell; 2003 Oct; 12(4):971-82. PubMed ID: 14580347
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
