These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
360 related articles for article (PubMed ID: 18483222)
1. PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling. Chen R; Liu M; Li H; Xue Y; Ramey WN; He N; Ai N; Luo H; Zhu Y; Zhou N; Zhou Q Genes Dev; 2008 May; 22(10):1356-68. PubMed ID: 18483222 [TBL] [Abstract][Full Text] [Related]
2. Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein. Bartholomeeusen K; Xiang Y; Fujinaga K; Peterlin BM J Biol Chem; 2012 Oct; 287(43):36609-16. PubMed ID: 22952229 [TBL] [Abstract][Full Text] [Related]
3. Disrupting the Cdk9/Cyclin T1 heterodimer of 7SK snRNP for the Brd4 and AFF1/4 guided reconstitution of active P-TEFb. Zhou K; Zhuang S; Liu F; Chen Y; Li Y; Wang S; Li Y; Wen H; Lin X; Wang J; Huang Y; He C; Xu N; Li Z; Xu L; Zhang Z; Chen LF; Chen R; Liu M Nucleic Acids Res; 2022 Jan; 50(2):750-762. PubMed ID: 34935961 [TBL] [Abstract][Full Text] [Related]
4. Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription. Liu P; Xiang Y; Fujinaga K; Bartholomeeusen K; Nilson KA; Price DH; Peterlin BM J Biol Chem; 2014 Apr; 289(14):9918-25. PubMed ID: 24515107 [TBL] [Abstract][Full Text] [Related]
5. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes. Dow EC; Liu H; Rice AP J Cell Physiol; 2010 Jul; 224(1):84-93. PubMed ID: 20201073 [TBL] [Abstract][Full Text] [Related]
6. PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation. Gudipaty SA; McNamara RP; Morton EL; D'Orso I Mol Cell Biol; 2015 Nov; 35(22):3810-28. PubMed ID: 26324325 [TBL] [Abstract][Full Text] [Related]
7. Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. Barboric M; Yik JH; Czudnochowski N; Yang Z; Chen R; Contreras X; Geyer M; Matija Peterlin B; Zhou Q Nucleic Acids Res; 2007; 35(6):2003-12. PubMed ID: 17341462 [TBL] [Abstract][Full Text] [Related]
8. The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK. Krueger BJ; Varzavand K; Cooper JJ; Price DH PLoS One; 2010 Aug; 5(8):e12335. PubMed ID: 20808803 [TBL] [Abstract][Full Text] [Related]
9. Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation. He N; Pezda AC; Zhou Q Mol Cell Biol; 2006 Oct; 26(19):7068-76. PubMed ID: 16980611 [TBL] [Abstract][Full Text] [Related]
10. The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming. Studniarek C; Tellier M; Martin PGP; Murphy S; Kiss T; Egloff S Cell Rep; 2021 Apr; 35(2):108965. PubMed ID: 33852864 [TBL] [Abstract][Full Text] [Related]
11. HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription. Contreras X; Barboric M; Lenasi T; Peterlin BM PLoS Pathog; 2007 Oct; 3(10):1459-69. PubMed ID: 17937499 [TBL] [Abstract][Full Text] [Related]
12. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes. Mbonye UR; Gokulrangan G; Datt M; Dobrowolski C; Cooper M; Chance MR; Karn J PLoS Pathog; 2013; 9(5):e1003338. PubMed ID: 23658523 [TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression. Mbonye UR; Wang B; Gokulrangan G; Chance MR; Karn J Proteomics; 2015 Jun; 15(12):2078-86. PubMed ID: 25900325 [TBL] [Abstract][Full Text] [Related]
14. Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation. Mbonye U; Wang B; Gokulrangan G; Shi W; Yang S; Karn J J Biol Chem; 2018 Jun; 293(26):10009-10025. PubMed ID: 29743242 [TBL] [Abstract][Full Text] [Related]
15. A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. He N; Jahchan NS; Hong E; Li Q; Bayfield MA; Maraia RJ; Luo K; Zhou Q Mol Cell; 2008 Mar; 29(5):588-99. PubMed ID: 18249148 [TBL] [Abstract][Full Text] [Related]
16. Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding. Cho WK; Jang MK; Huang K; Pise-Masison CA; Brady JN J Virol; 2010 Dec; 84(24):12801-9. PubMed ID: 20926576 [TBL] [Abstract][Full Text] [Related]
17. Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation. McNamara RP; McCann JL; Gudipaty SA; D'Orso I Cell Rep; 2013 Dec; 5(5):1256-68. PubMed ID: 24316072 [TBL] [Abstract][Full Text] [Related]
18. The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Faust TB; Li Y; Bacon CW; Jang GM; Weiss A; Jayaraman B; Newton BW; Krogan NJ; D'Orso I; Frankel AD Elife; 2018 May; 7():. PubMed ID: 29845934 [TBL] [Abstract][Full Text] [Related]
19. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. Schröder S; Cho S; Zeng L; Zhang Q; Kaehlcke K; Mak L; Lau J; Bisgrove D; Schnölzer M; Verdin E; Zhou MM; Ott M J Biol Chem; 2012 Jan; 287(2):1090-9. PubMed ID: 22084242 [TBL] [Abstract][Full Text] [Related]
20. Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Yik JH; Chen R; Nishimura R; Jennings JL; Link AJ; Zhou Q Mol Cell; 2003 Oct; 12(4):971-82. PubMed ID: 14580347 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]