360 related articles for article (PubMed ID: 18488193)
1. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
Fisher CD; Jackson JP; Lickteig AJ; Augustine LM; Cherrington NJ
Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
[TBL] [Abstract][Full Text] [Related]
2. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
Cheng X; Maher J; Dieter MZ; Klaassen CD
Drug Metab Dispos; 2005 Sep; 33(9):1276-82. PubMed ID: 15919853
[TBL] [Abstract][Full Text] [Related]
3. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.
Aleksunes LM; Klaassen CD
Drug Metab Dispos; 2012 Jul; 40(7):1366-79. PubMed ID: 22496397
[TBL] [Abstract][Full Text] [Related]
4. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
Buckley DB; Klaassen CD
Drug Metab Dispos; 2009 Apr; 37(4):847-56. PubMed ID: 19144771
[TBL] [Abstract][Full Text] [Related]
5. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
Cheng X; Klaassen CD
Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
[TBL] [Abstract][Full Text] [Related]
6. Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.
Fisher CD; Augustine LM; Maher JM; Nelson DM; Slitt AL; Klaassen CD; Lehman-McKeeman LD; Cherrington NJ
Drug Metab Dispos; 2007 Jun; 35(6):995-1000. PubMed ID: 17353348
[TBL] [Abstract][Full Text] [Related]
7. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
Wei P; Zhang J; Dowhan DH; Han Y; Moore DD
Pharmacogenomics J; 2002; 2(2):117-26. PubMed ID: 12049174
[TBL] [Abstract][Full Text] [Related]
8. Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin.
Lee SY; Lee JY; Kim YM; Kim SK; Oh SJ
Toxicol Lett; 2015 Jun; 235(2):107-15. PubMed ID: 25835148
[TBL] [Abstract][Full Text] [Related]
9. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
Park YJ; Lee EK; Lee YK; Park DJ; Jang HC; Moore DD
Toxicol Appl Pharmacol; 2012 Sep; 263(2):131-7. PubMed ID: 22503787
[TBL] [Abstract][Full Text] [Related]
10. Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse.
Wang Z; Wu Q; Li X; Klaunig JE
Arch Toxicol; 2020 Aug; 94(8):2873-2884. PubMed ID: 32435917
[TBL] [Abstract][Full Text] [Related]
11. Sex differences in the circadian variation of cytochrome p450 genes and corresponding nuclear receptors in mouse liver.
Lu YF; Jin T; Xu Y; Zhang D; Wu Q; Zhang YK; Liu J
Chronobiol Int; 2013 Nov; 30(9):1135-43. PubMed ID: 23926955
[TBL] [Abstract][Full Text] [Related]
12. Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.
Petrick JS; Klaassen CD
Drug Metab Dispos; 2007 Oct; 35(10):1806-15. PubMed ID: 17627975
[TBL] [Abstract][Full Text] [Related]
13. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
[TBL] [Abstract][Full Text] [Related]
14. Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants.
Yoshinari K; Okino N; Sato T; Sugatani J; Miwa M
Drug Metab Dispos; 2006 Jul; 34(7):1081-9. PubMed ID: 16581946
[TBL] [Abstract][Full Text] [Related]
15. The Nrf2 activator oltipraz also activates the constitutive androstane receptor.
Merrell MD; Jackson JP; Augustine LM; Fisher CD; Slitt AL; Maher JM; Huang W; Moore DD; Zhang Y; Klaassen CD; Cherrington NJ
Drug Metab Dispos; 2008 Aug; 36(8):1716-21. PubMed ID: 18474683
[TBL] [Abstract][Full Text] [Related]
16. The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.
Pacyniak EK; Cheng X; Cunningham ML; Crofton K; Klaassen CD; Guo GL
Toxicol Sci; 2007 May; 97(1):94-102. PubMed ID: 17324954
[TBL] [Abstract][Full Text] [Related]
17. Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease.
Wahlang B; Song M; Beier JI; Cameron Falkner K; Al-Eryani L; Clair HB; Prough RA; Osborne TS; Malarkey DE; States JC; Cave MC
Toxicol Appl Pharmacol; 2014 Sep; 279(3):380-390. PubMed ID: 24998970
[TBL] [Abstract][Full Text] [Related]
18. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.
Rooney JP; Oshida K; Kumar R; Baldwin WS; Corton JC
Toxicol Sci; 2019 Jan; 167(1):172-189. PubMed ID: 30203046
[TBL] [Abstract][Full Text] [Related]
19. Decreased PXR and CAR inhibit transporter and CYP mRNA Levels in the liver and intestine of mice with collagen-induced arthritis.
Kawase A; Yoshida I; Tsunokuni Y; Iwaki M
Xenobiotica; 2007 Apr; 37(4):366-74. PubMed ID: 17455111
[TBL] [Abstract][Full Text] [Related]
20. Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice.
Ip E; Farrell GC; Robertson G; Hall P; Kirsch R; Leclercq I
Hepatology; 2003 Jul; 38(1):123-32. PubMed ID: 12829994
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]