These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 18489907)

  • 1. Decrease in age-adjusted cerebrospinal fluid beta-secretase activity in Alzheimer's subjects.
    Wu G; Sankaranarayanan S; Tugusheva K; Kahana J; Seabrook G; Shi XP; King E; Devanarayan V; Cook JJ; Simon AJ
    Clin Biochem; 2008 Aug; 41(12):986-96. PubMed ID: 18489907
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease.
    Ewers M; Zhong Z; Bürger K; Wallin A; Blennow K; Teipel SJ; Shen Y; Hampel H
    Brain; 2008 May; 131(Pt 5):1252-8. PubMed ID: 18334538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.
    Zhong Z; Ewers M; Teipel S; Bürger K; Wallin A; Blennow K; He P; McAllister C; Hampel H; Shen Y
    Arch Gen Psychiatry; 2007 Jun; 64(6):718-26. PubMed ID: 17548753
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease.
    Zetterberg H; Andreasson U; Hansson O; Wu G; Sankaranarayanan S; Andersson ME; Buchhave P; Londos E; Umek RM; Minthon L; Simon AJ; Blennow K
    Arch Neurol; 2008 Aug; 65(8):1102-7. PubMed ID: 18695061
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease.
    Holsinger RM; McLean CA; Beyreuther K; Masters CL; Evin G
    Ann Neurol; 2002 Jun; 51(6):783-6. PubMed ID: 12112088
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
    Holsinger RM; McLean CA; Collins SJ; Masters CL; Evin G
    Ann Neurol; 2004 Jun; 55(6):898-9. PubMed ID: 15174031
    [No Abstract]   [Full Text] [Related]  

  • 7. Biochemical and cell-based assays for characterization of BACE-1 inhibitors.
    Pietrak BL; Crouthamel MC; Tugusheva K; Lineberger JE; Xu M; DiMuzio JM; Steele T; Espeseth AS; Stachel SJ; Coburn CA; Graham SL; Vacca JP; Shi XP; Simon AJ; Hazuda DJ; Lai MT
    Anal Biochem; 2005 Jul; 342(1):144-51. PubMed ID: 15958191
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.
    Ewers M; Cheng X; Zhong Z; Nural HF; Walsh C; Meindl T; Teipel SJ; Buerger K; He P; Shen Y; Hampel H
    J Alzheimers Dis; 2011; 25(2):373-81. PubMed ID: 21460439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H; Tabira T
    Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity.
    Fu H; Li W; Luo J; Lee NT; Li M; Tsim KW; Pang Y; Youdim MB; Han Y
    Biochem Biophys Res Commun; 2008 Feb; 366(3):631-6. PubMed ID: 18039469
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development and characterization of beta-secretase monolithic micro-immobilized enzyme reactor for on-line high-performance liquid chromatography studies.
    Mancini F; Naldi M; Cavrini V; Andrisano V
    J Chromatogr A; 2007 Dec; 1175(2):217-26. PubMed ID: 17991476
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of novel APP/Abeta isoforms in human cerebrospinal fluid.
    Portelius E; Brinkmalm G; Tran AJ; Zetterberg H; Westman-Brinkmalm A; Blennow K
    Neurodegener Dis; 2009; 6(3):87-94. PubMed ID: 19229112
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.
    Parsons RB; Austen BM
    Biochem Soc Trans; 2007 Nov; 35(Pt 5):974-9. PubMed ID: 17956258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Platelet beta-secretase activity is increased in Alzheimer's disease.
    Johnston JA; Liu WW; Coulson DT; Todd S; Murphy S; Brennan S; Foy CJ; Craig D; Irvine GB; Passmore AP
    Neurobiol Aging; 2008 May; 29(5):661-8. PubMed ID: 17174011
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of Cerebrospinal Fluid BACE1 Species.
    Lopez-Font I; Boix CP; Zetterberg H; Blennow K; Sáez-Valero J
    Mol Neurobiol; 2019 Dec; 56(12):8603-8616. PubMed ID: 31290061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease.
    Hampel H; Shen Y
    Scand J Clin Lab Invest; 2009; 69(1):8-12. PubMed ID: 18609117
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity.
    Hu H; Li H; Li J; Yu J; Tan L;
    BMC Med Genet; 2018 May; 19(1):75. PubMed ID: 29751835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primates.
    Sankaranarayanan S; Holahan MA; Colussi D; Crouthamel MC; Devanarayan V; Ellis J; Espeseth A; Gates AT; Graham SL; Gregro AR; Hazuda D; Hochman JH; Holloway K; Jin L; Kahana J; Lai MT; Lineberger J; McGaughey G; Moore KP; Nantermet P; Pietrak B; Price EA; Rajapakse H; Stauffer S; Steinbeiser MA; Seabrook G; Selnick HG; Shi XP; Stanton MG; Swestock J; Tugusheva K; Tyler KX; Vacca JP; Wong J; Wu G; Xu M; Cook JJ; Simon AJ
    J Pharmacol Exp Ther; 2009 Jan; 328(1):131-40. PubMed ID: 18854490
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of tetramic and tetronic acids as beta-secretase inhibitors.
    Larbig G; Schmidt B
    J Comb Chem; 2006; 8(4):480-90. PubMed ID: 16827559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. beta-Secretase expression in normal and functionally deprived rat olfactory bulbs: inverse correlation with oxidative metabolic activity.
    Yan XX; Xiong K; Luo XG; Struble RG; Clough RW
    J Comp Neurol; 2007 Mar; 501(1):52-69. PubMed ID: 17206602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.