BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 18490659)

  • 1. Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model.
    Toth K; Spencer JF; Dhar D; Sagartz JE; Buller RM; Painter GR; Wold WS
    Proc Natl Acad Sci U S A; 2008 May; 105(20):7293-7. PubMed ID: 18490659
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model.
    Tollefson AE; Spencer JF; Ying B; Buller RM; Wold WS; Toth K
    Antiviral Res; 2014 Dec; 112():38-46. PubMed ID: 25453340
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.
    Ying B; Tollefson AE; Spencer JF; Balakrishnan L; Dewhurst S; Capella C; Buller RM; Toth K; Wold WS
    Antimicrob Agents Chemother; 2014 Dec; 58(12):7171-81. PubMed ID: 25224011
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
    Toth K; Spencer JF; Ying B; Tollefson AE; Wold WSM
    Viruses; 2017 Jun; 9(6):. PubMed ID: 28608847
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.
    Toth K; Tollefson AE; Spencer JF; Ying B; Wold WSM
    Antiviral Res; 2017 Oct; 146():121-129. PubMed ID: 28827083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters.
    Tollefson AE; Riemann SB; Ying B; Spencer JF; Overhulse JM; Kashemirov BA; Wold WSM; McKenna CE; Toth K
    Antiviral Res; 2024 Feb; 222():105799. PubMed ID: 38190973
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters.
    Toth K; Ying B; Tollefson AE; Spencer JF; Balakrishnan L; Sagartz JE; Buller RM; Wold WS
    Viruses; 2015 Mar; 7(3):1409-28. PubMed ID: 25807051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir.
    Diaconu I; Cerullo V; Escutenaire S; Kanerva A; Bauerschmitz GJ; Hernandez-Alcoceba R; Pesonen S; Hemminki A
    J Gene Med; 2010 May; 12(5):435-45. PubMed ID: 20440754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients.
    Florescu DF; Pergam SA; Neely MN; Qiu F; Johnston C; Way S; Sande J; Lewinsohn DA; Guzman-Cottrill JA; Graham ML; Papanicolaou G; Kurtzberg J; Rigdon J; Painter W; Mommeja-Marin H; Lanier R; Anderson M; van der Horst C
    Biol Blood Marrow Transplant; 2012 May; 18(5):731-8. PubMed ID: 21963623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New drug on the horizon for treating adenovirus.
    Wold WS; Toth K
    Expert Opin Pharmacother; 2015; 16(14):2095-9. PubMed ID: 26330121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures.
    Jiang ZG; Cohen J; Marshall LJ; Major EO
    Antimicrob Agents Chemother; 2010 Nov; 54(11):4723-32. PubMed ID: 20823288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 1-O-hexadecyloxypropyl cidofovir (CMX001) effectively inhibits polyomavirus BK replication in primary human renal tubular epithelial cells.
    Rinaldo CH; Gosert R; Bernhoff E; Finstad S; Hirsch HH
    Antimicrob Agents Chemother; 2010 Nov; 54(11):4714-22. PubMed ID: 20713664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses.
    Florescu DF; Keck MA
    Expert Rev Anti Infect Ther; 2014 Oct; 12(10):1171-8. PubMed ID: 25120093
    [TBL] [Abstract][Full Text] [Related]  

  • 14. USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses.
    Toth K; Spencer JF; Ying B; Tollefson AE; Hartline CB; Richard ET; Fan J; Lyu J; Kashemirov BA; Harteg C; Reyna D; Lipka E; Prichard MN; McKenna CE; Wold WSM
    Antiviral Res; 2018 May; 153():1-9. PubMed ID: 29510156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiviral prophylaxis with twice daily topical cidofovir protects against challenge in the adenovirus type 5/New Zealand rabbit ocular model.
    Romanowski EG; Yates KA; Gordon YJ
    Antiviral Res; 2001 Dec; 52(3):275-80. PubMed ID: 11675144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001.
    Paolino K; Sande J; Perez E; Loechelt B; Jantausch B; Painter W; Anderson M; Tippin T; Lanier ER; Fry T; DeBiasi RL
    J Clin Virol; 2011 Feb; 50(2):167-70. PubMed ID: 21094081
    [TBL] [Abstract][Full Text] [Related]  

  • 17. N-chlorotaurine is an effective antiviral agent against adenovirus in vitro and in the Ad5/NZW rabbit ocular model.
    Romanowski EG; Yates KA; Teuchner B; Nagl M; Irschick EU; Gordon YJ
    Invest Ophthalmol Vis Sci; 2006 May; 47(5):2021-6. PubMed ID: 16639011
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clinical and in vitro evaluation of cidofovir for treatment of adenovirus infection in pediatric hematopoietic stem cell transplant recipients.
    Muller WJ; Levin MJ; Shin YK; Robinson C; Quinones R; Malcolm J; Hild E; Gao D; Giller R
    Clin Infect Dis; 2005 Dec; 41(12):1812-6. PubMed ID: 16288409
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CMX001 (1-O-hexadecyloxypropyl-cidofovir) inhibits polyomavirus JC replication in human brain progenitor-derived astrocytes.
    Gosert R; Rinaldo CH; Wernli M; Major EO; Hirsch HH
    Antimicrob Agents Chemother; 2011 May; 55(5):2129-36. PubMed ID: 21402853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Drug development against human adenoviruses and its advancement by Syrian hamster models.
    Wold WSM; Tollefson AE; Ying B; Spencer JF; Toth K
    FEMS Microbiol Rev; 2019 Jul; 43(4):380-388. PubMed ID: 30916746
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.