These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 18495438)

  • 1. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.
    Leachman SA; Hickerson RP; Hull PR; Smith FJ; Milstone LM; Lane EB; Bale SJ; Roop DR; McLean WH; Kaspar RL
    J Dermatol Sci; 2008 Sep; 51(3):151-7. PubMed ID: 18495438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Single-nucleotide-specific siRNA targeting in a dominant-negative skin model.
    Hickerson RP; Smith FJ; Reeves RE; Contag CH; Leake D; Leachman SA; Milstone LM; McLean WH; Kaspar RL
    J Invest Dermatol; 2008 Mar; 128(3):594-605. PubMed ID: 17914454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapeutic interference: a step closer for pachyonychia congenita?
    Rugg EL
    J Invest Dermatol; 2008 Jan; 128(1):7-8. PubMed ID: 18071332
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of quantitative molecular clinical end points for siRNA clinical trials.
    Hickerson RP; Leachman SA; Pho LN; Gonzalez-Gonzalez E; Smith FJ; McLean WH; Contag CH; Leake D; Milstone LM; Kaspar RL
    J Invest Dermatol; 2011 May; 131(5):1029-36. PubMed ID: 21191405
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model.
    Hickerson RP; Flores MA; Leake D; Lara MF; Contag CH; Leachman SA; Kaspar RL
    J Invest Dermatol; 2011 May; 131(5):1037-44. PubMed ID: 21248764
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SiRNA-mediated selective inhibition of mutant keratin mRNAs responsible for the skin disorder pachyonychia congenita.
    Hickerson RP; Smith FJ; McLean WH; Landthaler M; Leube RE; Kaspar RL
    Ann N Y Acad Sci; 2006 Oct; 1082():56-61. PubMed ID: 17145926
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of therapeutic siRNAs for pachyonychia congenita.
    Smith FJ; Hickerson RP; Sayers JM; Reeves RE; Contag CH; Leake D; Kaspar RL; McLean WH
    J Invest Dermatol; 2008 Jan; 128(1):50-8. PubMed ID: 17762855
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapy for dominant inherited diseases by allele-specific RNA interference: successes and pitfalls.
    Trochet D; Prudhon B; Vassilopoulos S; Bitoun M
    Curr Gene Ther; 2015; 15(5):503-10. PubMed ID: 26264709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel H1 mutation in keratin 6a in an infant with pachyonychia congenita.
    Luo S; Luo Q; Zhang H; Wan C
    Indian J Dermatol Venereol Leprol; 2015; 81(4):385-7. PubMed ID: 26087092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pachyonychia congenita patients with mutations in KRT6A have more extensive disease compared with patients who have mutations in KRT16.
    Spaunhurst KM; Hogendorf AM; Smith FJ; Lingala B; Schwartz ME; Cywinska-Bernas A; Zeman KJ; Tang JY
    Br J Dermatol; 2012 Apr; 166(4):875-8. PubMed ID: 22098151
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Revisiting pachyonychia congenita: a case-cohort study of 815 patients.
    Samuelov L; Smith FJD; Hansen CD; Sprecher E
    Br J Dermatol; 2020 Mar; 182(3):738-746. PubMed ID: 31823354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pachyonychia congenita responding favorably to a combination of surgical and medical therapies.
    Daroach M; Dogra S; Bhattacharjee R; Tp A; Smith F; Mahajan R
    Dermatol Ther; 2019 Sep; 32(5):e13045. PubMed ID: 31364784
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development of skin-humanized mouse models of pachyonychia congenita.
    García M; Larcher F; Hickerson RP; Baselga E; Leachman SA; Kaspar RL; Del Rio M
    J Invest Dermatol; 2011 May; 131(5):1053-60. PubMed ID: 21150925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pachyonychia congenita: a case report of a successful treatment with rosuvastatin in a patient with a KRT6A mutation.
    Abdollahimajd F; Rajabi F; Shahidi-Dadras M; Saket S; Youssefian L; Vahidnezhad H; Uitto J
    Br J Dermatol; 2019 Sep; 181(3):584-586. PubMed ID: 30307612
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.
    Eliason MJ; Leachman SA; Feng BJ; Schwartz ME; Hansen CD
    J Am Acad Dermatol; 2012 Oct; 67(4):680-6. PubMed ID: 22264670
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toward a treatment for pachyonychia congenita: report on the 7th Annual International Pachyonychia Congenita Consortium meeting.
    Kaspar RL; Leachman SA; McLean WH; Schwartz ME
    J Invest Dermatol; 2011 May; 131(5):1011-4. PubMed ID: 21494242
    [No Abstract]   [Full Text] [Related]  

  • 17. Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients.
    Hickerson RP; Leake D; Pho LN; Leachman SA; Kaspar RL
    J Dermatol Sci; 2009 Nov; 56(2):82-8. PubMed ID: 19699613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early severe pachyonychia congenita subtype PC-K6a with a novel mutation in the KRT6A gene.
    Cammarata-Scalisi F; Natsuga K; Toyonaga E; Nishie W; Shimizu H; Avendaño A; Araque D; Da Silva G; Bellacchio E; Callea M
    J Eur Acad Dermatol Venereol; 2017 Feb; 31(2):e94-e96. PubMed ID: 27445120
    [No Abstract]   [Full Text] [Related]  

  • 19. First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.
    Leachman SA; Hickerson RP; Schwartz ME; Bullough EE; Hutcherson SL; Boucher KM; Hansen CD; Eliason MJ; Srivatsa GS; Kornbrust DJ; Smith FJ; McLean WI; Milstone LM; Kaspar RL
    Mol Ther; 2010 Feb; 18(2):442-6. PubMed ID: 19935778
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pachyonychia Congenita: A Spectrum of KRT6a Mutations in Australian Patients.
    Forrest CE; Casey G; Mordaunt DA; Thompson EM; Gordon L
    Pediatr Dermatol; 2016 May; 33(3):337-42. PubMed ID: 27041546
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.