BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

548 related articles for article (PubMed ID: 18495536)

  • 1. Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial.
    Park BH; Hwang T; Liu TC; Sze DY; Kim JS; Kwon HC; Oh SY; Han SY; Yoon JH; Hong SH; Moon A; Speth K; Park C; Ahn YJ; Daneshmand M; Rhee BG; Pinedo HM; Bell JC; Kirn DH
    Lancet Oncol; 2008 Jun; 9(6):533-42. PubMed ID: 18495536
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A smart move against cancer for vaccinia virus.
    Alemany R
    Lancet Oncol; 2008 Jun; 9(6):507-8. PubMed ID: 18510983
    [No Abstract]   [Full Text] [Related]  

  • 3. Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer.
    Park SH; Breitbach CJ; Lee J; Park JO; Lim HY; Kang WK; Moon A; Mun JH; Sommermann EM; Maruri Avidal L; Patt R; Pelusio A; Burke J; Hwang TH; Kirn D; Park YS
    Mol Ther; 2015 Sep; 23(9):1532-40. PubMed ID: 26073886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinoma.
    Liu TC; Hwang T; Park BH; Bell J; Kirn DH
    Mol Ther; 2008 Sep; 16(9):1637-42. PubMed ID: 18628758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. JX-594, a targeted oncolytic poxvirus for the treatment of cancer.
    Merrick AE; Ilett EJ; Melcher AA
    Curr Opin Investig Drugs; 2009 Dec; 10(12):1372-82. PubMed ID: 19943208
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mechanistic proof-of-concept clinical trial with JX-594, a targeted multi-mechanistic oncolytic poxvirus, in patients with metastatic melanoma.
    Hwang TH; Moon A; Burke J; Ribas A; Stephenson J; Breitbach CJ; Daneshmand M; De Silva N; Parato K; Diallo JS; Lee YS; Liu TC; Bell JC; Kirn DH
    Mol Ther; 2011 Oct; 19(10):1913-22. PubMed ID: 21772252
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer.
    Heo J; Reid T; Ruo L; Breitbach CJ; Rose S; Bloomston M; Cho M; Lim HY; Chung HC; Kim CW; Burke J; Lencioni R; Hickman T; Moon A; Lee YS; Kim MK; Daneshmand M; Dubois K; Longpre L; Ngo M; Rooney C; Bell JC; Rhee BG; Patt R; Hwang TH; Kirn DH
    Nat Med; 2013 Mar; 19(3):329-36. PubMed ID: 23396206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model.
    Lee JH; Roh MS; Lee YK; Kim MK; Han JY; Park BH; Trown P; Kirn DH; Hwang TH
    Cancer Gene Ther; 2010 Feb; 17(2):73-9. PubMed ID: 19629143
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans.
    Breitbach CJ; Arulanandam R; De Silva N; Thorne SH; Patt R; Daneshmand M; Moon A; Ilkow C; Burke J; Hwang TH; Heo J; Cho M; Chen H; Angarita FA; Addison C; McCart JA; Bell JC; Kirn DH
    Cancer Res; 2013 Feb; 73(4):1265-75. PubMed ID: 23393196
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Systemic armed oncolytic and immunologic therapy for cancer with JX-594, a targeted poxvirus expressing GM-CSF.
    Kim JH; Oh JY; Park BH; Lee DE; Kim JS; Park HE; Roh MS; Je JE; Yoon JH; Thorne SH; Kirn D; Hwang TH
    Mol Ther; 2006 Sep; 14(3):361-70. PubMed ID: 16905462
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted and armed oncolytic poxviruses for cancer: the lead example of JX-594.
    Breitbach CJ; Thorne SH; Bell JC; Kirn DH
    Curr Pharm Biotechnol; 2012 Jul; 13(9):1768-72. PubMed ID: 21740365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oncolytic and immunologic cancer therapy with GM-CSF-armed vaccinia virus of Tian Tan strain Guang9.
    Deng L; Fan J; Guo M; Huang B
    Cancer Lett; 2016 Mar; 372(2):251-7. PubMed ID: 26803055
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy.
    Heo J; Breitbach CJ; Moon A; Kim CW; Patt R; Kim MK; Lee YK; Oh SY; Woo HY; Parato K; Rintoul J; Falls T; Hickman T; Rhee BG; Bell JC; Kirn DH; Hwang TH
    Mol Ther; 2011 Jun; 19(6):1170-9. PubMed ID: 21427706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Holmium-166 radioembolisation in patients with unresectable, chemorefractory liver metastases (HEPAR trial): a phase 1, dose-escalation study.
    Smits ML; Nijsen JF; van den Bosch MA; Lam MG; Vente MA; Mali WP; van Het Schip AD; Zonnenberg BA
    Lancet Oncol; 2012 Oct; 13(10):1025-34. PubMed ID: 22920685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tolerability, safety, pharmacokinetics, and efficacy of doxorubicin-loaded anti-EGFR immunoliposomes in advanced solid tumours: a phase 1 dose-escalation study.
    Mamot C; Ritschard R; Wicki A; Stehle G; Dieterle T; Bubendorf L; Hilker C; Deuster S; Herrmann R; Rochlitz C
    Lancet Oncol; 2012 Dec; 13(12):1234-41. PubMed ID: 23153506
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients.
    Li JL; Liu HL; Zhang XR; Xu JP; Hu WK; Liang M; Chen SY; Hu F; Chu DT
    Gene Ther; 2009 Mar; 16(3):376-82. PubMed ID: 19092859
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Phase 2, Open-Label, Randomized Study of Pexa-Vec (JX-594) Administered by Intratumoral Injection in Patients with Unresectable Primary Hepatocellular Carcinoma.
    Breitbach CJ; Moon A; Burke J; Hwang TH; Kirn DH
    Methods Mol Biol; 2015; 1317():343-57. PubMed ID: 26072416
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers.
    Parato KA; Breitbach CJ; Le Boeuf F; Wang J; Storbeck C; Ilkow C; Diallo JS; Falls T; Burns J; Garcia V; Kanji F; Evgin L; Hu K; Paradis F; Knowles S; Hwang TH; Vanderhyden BC; Auer R; Kirn DH; Bell JC
    Mol Ther; 2012 Apr; 20(4):749-58. PubMed ID: 22186794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma.
    Senzer NN; Kaufman HL; Amatruda T; Nemunaitis M; Reid T; Daniels G; Gonzalez R; Glaspy J; Whitman E; Harrington K; Goldsweig H; Marshall T; Love C; Coffin R; Nemunaitis JJ
    J Clin Oncol; 2009 Dec; 27(34):5763-71. PubMed ID: 19884534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phase 1 study of intratumoral Pexa-Vec (JX-594), an oncolytic and immunotherapeutic vaccinia virus, in pediatric cancer patients.
    Cripe TP; Ngo MC; Geller JI; Louis CU; Currier MA; Racadio JM; Towbin AJ; Rooney CM; Pelusio A; Moon A; Hwang TH; Burke JM; Bell JC; Kirn DH; Breitbach CJ
    Mol Ther; 2015 Mar; 23(3):602-8. PubMed ID: 25531693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.