These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 18495615)

  • 1. The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer.
    Johannissen LO; Scrutton NS; Sutcliffe MJ
    J R Soc Interface; 2008 Dec; 5 Suppl 3(Suppl 3):S225-32. PubMed ID: 18495615
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proton tunneling in aromatic amine dehydrogenase is driven by a short-range sub-picosecond promoting vibration: consistency of simulation and theory with experiment.
    Johannissen LO; Hay S; Scrutton NS; Sutcliffe MJ
    J Phys Chem B; 2007 Mar; 111(10):2631-8. PubMed ID: 17305385
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of classical and quantum paths for deprotonation of methylamine by methylamine dehydrogenase.
    Ranaghan KE; Masgrau L; Scrutton NS; Sutcliffe MJ; Mulholland AJ
    Chemphyschem; 2007 Aug; 8(12):1816-35. PubMed ID: 17676581
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tunneling and classical paths for proton transfer in an enzyme reaction dominated by tunneling: oxidation of tryptamine by aromatic amine dehydrogenase.
    Masgrau L; Ranaghan KE; Scrutton NS; Mulholland AJ; Sutcliffe MJ
    J Phys Chem B; 2007 Mar; 111(11):3032-47. PubMed ID: 17388439
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ab Initio QM/MM Modeling of the Rate-Limiting Proton Transfer Step in the Deamination of Tryptamine by Aromatic Amine Dehydrogenase.
    Ranaghan KE; Morris WG; Masgrau L; Senthilkumar K; Johannissen LO; Scrutton NS; Harvey JN; Manby FR; Mulholland AJ
    J Phys Chem B; 2017 Oct; 121(42):9785-9798. PubMed ID: 28930453
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Computer simulations of quantum tunnelling in enzyme-catalysed hydrogen transfer reactions.
    Ranaghan KE; Mulholland AJ
    Interdiscip Sci; 2010 Mar; 2(1):78-97. PubMed ID: 20640799
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Importance of barrier shape in enzyme-catalyzed reactions. Vibrationally assisted hydrogen tunneling in tryptophan tryptophylquinone-dependent amine dehydrogenases.
    Basran J; Patel S; Sutcliffe MJ; Scrutton NS
    J Biol Chem; 2001 Mar; 276(9):6234-42. PubMed ID: 11087744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Driving force analysis of proton tunnelling across a reactivity series for an enzyme-substrate complex.
    Hothi P; Hay S; Roujeinikova A; Sutcliffe MJ; Lee M; Leys D; Cullis PM; Scrutton NS
    Chembiochem; 2008 Nov; 9(17):2839-45. PubMed ID: 19012287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Incorporating Fast Protein Dynamics into Enzyme Design: A Proposed Mutant Aromatic Amine Dehydrogenase.
    Zoi I; Antoniou D; Schwartz SD
    J Phys Chem B; 2017 Aug; 121(30):7290-7298. PubMed ID: 28696108
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems.
    Sutcliffe MJ; Masgrau L; Roujeinikova A; Johannissen LO; Hothi P; Basran J; Ranaghan KE; Mulholland AJ; Leys D; Scrutton NS
    Philos Trans R Soc Lond B Biol Sci; 2006 Aug; 361(1472):1375-86. PubMed ID: 16873125
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Barrier compression and its contribution to both classical and quantum mechanical aspects of enzyme catalysis.
    Hay S; Johannissen LO; Sutcliffe MJ; Scrutton NS
    Biophys J; 2010 Jan; 98(1):121-8. PubMed ID: 20085724
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Redox properties of tryptophan tryptophylquinone enzymes. Correlation with structure and reactivity.
    Zhu Z; Davidson VL
    J Biol Chem; 1998 Jun; 273(23):14254-60. PubMed ID: 9603931
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gated and ungated electron transfer reactions from aromatic amine dehydrogenase to azurin.
    Hyun YL; Zhu Z; Davidson VL
    J Biol Chem; 1999 Oct; 274(41):29081-6. PubMed ID: 10506161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assignment of the vibrational spectra of enzyme-bound tryptophan tryptophyl quinones using a combined QM/MM approach.
    Pang J; Scrutton NS; de Visser SP; Sutcliffe MJ
    J Phys Chem A; 2010 Jan; 114(2):1212-7. PubMed ID: 19950920
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Does the pressure dependence of kinetic isotope effects report usefully on dynamics in enzyme H-transfer reactions?
    Hoeven R; Heyes DJ; Hay S; Scrutton NS
    FEBS J; 2015 Aug; 282(16):3243-55. PubMed ID: 25581554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An analysis of reaction pathways for proton tunnelling in methylamine dehydrogenase.
    Nuñez S; Tresadern G; Hillier IH; Burton NA
    Philos Trans R Soc Lond B Biol Sci; 2006 Aug; 361(1472):1387-98. PubMed ID: 16873126
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pressure effects on enzyme-catalyzed quantum tunneling events arise from protein-specific structural and dynamic changes.
    Hay S; Johannissen LO; Hothi P; Sutcliffe MJ; Scrutton NS
    J Am Chem Soc; 2012 Jun; 134(23):9749-54. PubMed ID: 22632111
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Atomic description of an enzyme reaction dominated by proton tunneling.
    Masgrau L; Roujeinikova A; Johannissen LO; Hothi P; Basran J; Ranaghan KE; Mulholland AJ; Sutcliffe MJ; Scrutton NS; Leys D
    Science; 2006 Apr; 312(5771):237-41. PubMed ID: 16614214
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Electron transfer reactions between aromatic amine dehydrogenase and azurin.
    Hyun YL; Davidson VL
    Biochemistry; 1995 Sep; 34(38):12249-54. PubMed ID: 7547967
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Free-Energy Landscape and Proton Transfer Pathways in Oxidative Deamination by Methylamine Dehydrogenase.
    Zelleke T; Marx D
    Chemphyschem; 2017 Jan; 18(2):208-222. PubMed ID: 27860041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.