BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 1850098)

  • 1. The epidermal growth factor receptor phosphorylates GTPase-activating protein (GAP) at Tyr-460, adjacent to the GAP SH2 domains.
    Liu XQ; Pawson T
    Mol Cell Biol; 1991 May; 11(5):2511-6. PubMed ID: 1850098
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activated Src tyrosine kinase phosphorylates Tyr-457 of bovine GTPase-activating protein (GAP) in vitro and the corresponding residue of rat GAP in vivo.
    Park S; Liu X; Pawson T; Jove R
    J Biol Chem; 1992 Aug; 267(24):17194-200. PubMed ID: 1512257
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of the ras GTPase-activating protein (GAP) by the p93c-fes protein-tyrosine kinase in vitro and formation of GAP-fes complexes via an SH2 domain-dependent mechanism.
    Hjermstad SJ; Briggs SD; Smithgall TE
    Biochemistry; 1993 Oct; 32(39):10519-25. PubMed ID: 7691175
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosine phosphorylation of Ras GTPase-activating protein stabilizes its association with p62 at membranes of v-Src transformed cells.
    Park S; Jove R
    J Biol Chem; 1993 Dec; 268(34):25728-34. PubMed ID: 7503985
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of residues in GTPase-activating protein Src homology 2 domains that control binding to tyrosine phosphorylated growth factor receptors and p62.
    Marengere LE; Pawson T
    J Biol Chem; 1992 Nov; 267(32):22779-86. PubMed ID: 1385407
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase.
    Cooper JA; Kashishian A
    Mol Cell Biol; 1993 Mar; 13(3):1737-45. PubMed ID: 8382774
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.
    Bouton AH; Kanner SB; Vines RR; Wang HC; Gibbs JB; Parsons JT
    Mol Cell Biol; 1991 Feb; 11(2):945-53. PubMed ID: 1703633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Src homology region 2 domains direct protein-protein interactions in signal transduction.
    Moran MF; Koch CA; Anderson D; Ellis C; England L; Martin GS; Pawson T
    Proc Natl Acad Sci U S A; 1990 Nov; 87(21):8622-6. PubMed ID: 2236073
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of the C-terminal domain of ras-GTPase-activating protein (ras-GAP) as substrate for epidermal growth factor receptor and p60c-src kinase.
    Borowski P; Kornetzky L; Heiland M; Roloff S; Weber W; Laufs R
    Biochem Mol Biol Int; 1996 Jun; 39(3):635-46. PubMed ID: 8828816
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases.
    Schlaepfer DD; Hunter T
    Mol Cell Biol; 1996 Oct; 16(10):5623-33. PubMed ID: 8816475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
    van der Geer P; Wiley S; Lai VK; Olivier JP; Gish GD; Stephens R; Kaplan D; Shoelson S; Pawson T
    Curr Biol; 1995 Apr; 5(4):404-12. PubMed ID: 7542991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation.
    Roof RW; Haskell MD; Dukes BD; Sherman N; Kinter M; Parsons SJ
    Mol Cell Biol; 1998 Dec; 18(12):7052-63. PubMed ID: 9819392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases.
    Ellis C; Moran M; McCormick F; Pawson T
    Nature; 1990 Jan; 343(6256):377-81. PubMed ID: 1689011
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.
    Gill K; Macdonald-Obermann JL; Pike LJ
    J Biol Chem; 2017 Dec; 292(50):20744-20755. PubMed ID: 29074618
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tyrosine phosphorylation of ras GTPase-activating protein does not require association with the epidermal growth factor receptor.
    Soler C; Beguinot L; Sorkin A; Carpenter G
    J Biol Chem; 1993 Oct; 268(29):22010-9. PubMed ID: 8408058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck.
    Briggs SD; Bryant SS; Jove R; Sanderson SD; Smithgall TE
    J Biol Chem; 1995 Jun; 270(24):14718-24. PubMed ID: 7782336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma.
    Margolis B; Li N; Koch A; Mohammadi M; Hurwitz DR; Zilberstein A; Ullrich A; Pawson T; Schlessinger J
    EMBO J; 1990 Dec; 9(13):4375-80. PubMed ID: 2176151
    [TBL] [Abstract][Full Text] [Related]  

  • 18. c-Src phosphorylates epidermal growth factor receptor on tyrosine 845.
    Sato K; Sato A; Aoto M; Fukami Y
    Biochem Biophys Res Commun; 1995 Oct; 215(3):1078-87. PubMed ID: 7488034
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple SH2-mediated interactions in v-src-transformed cells.
    Koch CA; Moran MF; Anderson D; Liu XQ; Mbamalu G; Pawson T
    Mol Cell Biol; 1992 Mar; 12(3):1366-74. PubMed ID: 1545818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.
    Wick MJ; Dong LQ; Hu D; Langlais P; Liu F
    J Biol Chem; 2001 Nov; 276(46):42843-50. PubMed ID: 11551902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.