235 related articles for article (PubMed ID: 18501591)
1. 1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells.
Ishizuka S; Kurihara N; Hiruma Y; Miura D; Namekawa J; Tamura A; Kato-Nakamura Y; Nakano Y; Takenouchi K; Hashimoto Y; Nagasawa K; Roodman GD
J Steroid Biochem Mol Biol; 2008 Jun; 110(3-5):269-77. PubMed ID: 18501591
[TBL] [Abstract][Full Text] [Related]
2. Novel vitamin D3 analogs, 1alpha, 25(OH)2D(3)-26, 23-lactam (DLAMs), antagonize bone resorption via suppressing RANKL expression in osteoblasts.
Inada M; Tsukamoto K; Hirata M; Takita M; Nagasawa K; Miyaura C
Biochem Biophys Res Commun; 2008 Aug; 372(3):434-9. PubMed ID: 18489902
[TBL] [Abstract][Full Text] [Related]
3. Antagonistic action of novel 1alpha,25-dihydroxyvitamin D3-26, 23-lactone analogs on differentiation of human leukemia cells (HL-60) induced by 1alpha,25-dihydroxyvitamin D3.
Miura D; Manabe K; Ozono K; Saito M; Gao Q; Norman AW; Ishizuka S
J Biol Chem; 1999 Jun; 274(23):16392-9. PubMed ID: 10347199
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.
Kato Y; Nakano Y; Sano H; Tanatani A; Kobayashi H; Shimazawa R; Koshino H; Hashimoto Y; Nagasawa K
Bioorg Med Chem Lett; 2004 May; 14(10):2579-83. PubMed ID: 15109656
[TBL] [Abstract][Full Text] [Related]
5. (23S)-25-Dehydro-1{alpha}-hydroxyvitamin D3-26,23-lactone, a vitamin D receptor antagonist that inhibits osteoclast formation and bone resorption in bone marrow cultures from patients with Paget's disease.
Ishizuka S; Kurihara N; Reddy SV; Cornish J; Cundy T; Roodman GD
Endocrinology; 2005 Apr; 146(4):2023-30. PubMed ID: 15618361
[TBL] [Abstract][Full Text] [Related]
6. (23S)- and (23R)-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactone function as antagonists of vitamin D receptor-mediated genomic actions of 1alpha,25-dihydroxyvitamin D(3).
Ishizuka S; Miura D; Ozono K; Saito M; Eguchi H; Chokki M; Norman AW
Steroids; 2001; 66(3-5):227-37. PubMed ID: 11179730
[TBL] [Abstract][Full Text] [Related]
7. Antagonistic action of novel 1alpha,25-dihydroxyvitamin D(3)-26, 23-lactone analogs on 25-hydroxyvitamin-D(3)-24-hydroxylase gene expression induced by 1alpha,25-dihydroxy-vitamin D(3) in human promyelocytic leukemia (HL-60) cells.
Ishizuka S; Miura D; Eguchi H; Ozono K; Chokki M; Kamimura T; Norman AW
Arch Biochem Biophys; 2000 Aug; 380(1):92-102. PubMed ID: 10900137
[TBL] [Abstract][Full Text] [Related]
8. Structure-activity relationship studies on vitamin D lactam derivatives as vitamin D receptor antagonist.
Cho K; Uneuchi F; Kato-Nakamura Y; Namekawa J; Ishizuka S; Takenouchi K; Nagasawa K
Bioorg Med Chem Lett; 2008 Aug; 18(15):4287-90. PubMed ID: 18635349
[TBL] [Abstract][Full Text] [Related]
9. Practical synthesis and evaluation of the biological activities of 1alpha,25-dihydroxyvitamin D3 antagonists, 1alpha,25-dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesis.
Nakano Y; Kato Y; Imai K; Ochiai E; Namekawa J; Ishizuka S; Takenouchi K; Tanatani A; Hashimoto Y; Nagasawa K
J Med Chem; 2006 Apr; 49(8):2398-406. PubMed ID: 16610783
[TBL] [Abstract][Full Text] [Related]
10. 1alpha,25-dihydroxyvitamin D(3)-26,23-lactone analogs antagonize differentiation of human leukemia cells (HL-60 cells) but not of human acute promyelocytic leukemia cells (NB4 cells).
Miura D; Manabe K; Gao Q; Norman AW; Ishizuka S
FEBS Lett; 1999 Oct; 460(2):297-302. PubMed ID: 10544253
[TBL] [Abstract][Full Text] [Related]
11. Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1alpha,25-dihydroxyvitamin D3 from pagetic bone marrow cells.
Ishizuka S; Kurihara N; Miura D; Takenouchi K; Cornish J; Cundy T; Reddy SV; Roodman GD
J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):331-4. PubMed ID: 15225795
[TBL] [Abstract][Full Text] [Related]
12. Differential gene regulation by a synthetic vitamin D receptor ligand and active vitamin D in human cells.
Iwaki M; Kanemoto Y; Sawada T; Nojiri K; Kurokawa T; Tsutsumi R; Nagasawa K; Kato S
PLoS One; 2023; 18(12):e0295288. PubMed ID: 38091304
[TBL] [Abstract][Full Text] [Related]
13. Synthetic studies of (23S,25R)-1α,25-dihydroxyvitamin D
Akagi Y; Nagata A; Odagi M; Nagasawa K
J Steroid Biochem Mol Biol; 2018 Mar; 177():240-246. PubMed ID: 28757443
[TBL] [Abstract][Full Text] [Related]
14. Singly dehydroxylated A-ring analogues of 19-nor-1alpha,25-dihydroxyvitamin D3 and 19-nor-22-oxa-1alpha,25-dihydroxyvitamin D3: novel vitamin D3 analogues with potent transcriptional activity but extremely low affinity for vitamin D receptor.
Okano T; Nakagawa K; Tsugawa N; Ozono K; Kubodera N; Osawa A; Terada M; Mikami K
Biol Pharm Bull; 1998 Dec; 21(12):1300-5. PubMed ID: 9881643
[TBL] [Abstract][Full Text] [Related]
15. Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
Nakagawa K; Kurobe M; Ozono K; Konno K; Fujishima T; Takayama H; Okano T
Biochem Pharmacol; 2000 Mar; 59(6):691-702. PubMed ID: 10677586
[TBL] [Abstract][Full Text] [Related]
16. 25-Dehydro-1alpha-hydroxyvitamin D3-26,23S-lactone antagonizes the nuclear vitamin D receptor by mediating a unique noncovalent conformational change.
Bula CM; Bishop JE; Ishizuka S; Norman AW
Mol Endocrinol; 2000 Nov; 14(11):1788-96. PubMed ID: 11075812
[TBL] [Abstract][Full Text] [Related]
17. Mechanistic studies to evaluate the enhanced antiproliferation of human keratinocytes by 1alpha,25-dihydroxyvitamin D(3)-3-bromoacetate, a covalent modifier of vitamin D receptor, compared to 1alpha,25-dihydroxyvitamin D(3).
Chen ML; Ray S; Swamy N; Holick MF; Ray R
Arch Biochem Biophys; 1999 Oct; 370(1):34-44. PubMed ID: 10496974
[TBL] [Abstract][Full Text] [Related]
18. Natural metabolites of 1alpha,25-dihydroxyvitamin D(3) retain biologic activity mediated through the vitamin D receptor.
Harant H; Spinner D; Reddy GS; Lindley IJ
J Cell Biochem; 2000 Apr; 78(1):112-20. PubMed ID: 10797570
[TBL] [Abstract][Full Text] [Related]
19. The 3-epi- and 24-oxo-derivatives of 1alpha,25 dihydroxyvitamin D(3) stimulate transcription through the vitamin D receptor.
Messerlian S; Gao X; St-Arnaud R
J Steroid Biochem Mol Biol; 2000; 72(1-2):29-34. PubMed ID: 10731635
[TBL] [Abstract][Full Text] [Related]
20. Antagonistic Actions in Vivo of (23S)-25-Dehydro-1alpha-Hydroxyvitamin D(3-)26,23-Lactone on Calcium Metabolism Induced by 1alpha,25-Dihydroxyvitamin D(3).
Ishizuka S; Miura D; Ozono K; Chokki M; Mimura H; Norman AW
Endocrinology; 2001 Jan; 142(1):59-67. PubMed ID: 11145567
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
