BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 18504436)

  • 1. Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters.
    Petrie K; Guidez F; Zhu J; Howell L; Owen G; Chew YP; Parks S; Waxman S; Licht J; Mittnacht S; Zelent A
    Oncogene; 2008 Sep; 27(39):5260-6. PubMed ID: 18504436
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fusion protein of retinoic acid receptor alpha with promyelocytic leukemia protein or promyelocytic leukemia zinc finger protein recruits N-CoR-TBLR1 corepressor complex to repress transcription in vivo.
    Tomita A; Buchholz DR; Obata K; Shi YB
    J Biol Chem; 2003 Aug; 278(33):30788-95. PubMed ID: 12794076
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia.
    Hong SH; David G; Wong CW; Dejean A; Privalsky ML
    Proc Natl Acad Sci U S A; 1997 Aug; 94(17):9028-33. PubMed ID: 9256429
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.
    Guidez F; Ivins S; Zhu J; Söderström M; Waxman S; Zelent A
    Blood; 1998 Apr; 91(8):2634-42. PubMed ID: 9531570
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.
    Guidez F; Parks S; Wong H; Jovanovic JV; Mays A; Gilkes AF; Mills KI; Guillemin MC; Hobbs RM; Pandolfi PP; de Thé H; Solomon E; Grimwade D
    Proc Natl Acad Sci U S A; 2007 Nov; 104(47):18694-9. PubMed ID: 18000064
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PML-RARalpha alleviates the transcriptional repression mediated by tumor suppressor Rb.
    Khan MM; Nomura T; Kim H; Kaul SC; Wadhwa R; Zhong S; Pandolfi PP; Ishii S
    J Biol Chem; 2001 Nov; 276(47):43491-4. PubMed ID: 11583987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promyelocytic leukemia zinc finger-retinoic acid receptor α (PLZF-RARα), an oncogenic transcriptional repressor of cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) and tumor protein p53 (TP53) genes.
    Choi WI; Yoon JH; Kim MY; Koh DI; Licht JD; Kim K; Hur MW
    J Biol Chem; 2014 Jul; 289(27):18641-56. PubMed ID: 24821728
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein.
    Dong S; Zhu J; Reid A; Strutt P; Guidez F; Zhong HJ; Wang ZY; Licht J; Waxman S; Chomienne C; Chen Z; Zelent A; Chen SJ
    Proc Natl Acad Sci U S A; 1996 Apr; 93(8):3624-9. PubMed ID: 8622986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.
    Puccetti E; Sennewald B; Fosca-Ferrara F; Boehrer S; Bianchini A; Hoelzer D; Ottmann OG; Nervi C; Ruthardt M
    Hematol J; 2001; 2(6):385-92. PubMed ID: 11920278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.
    He LZ; Guidez F; Tribioli C; Peruzzi D; Ruthardt M; Zelent A; Pandolfi PP
    Nat Genet; 1998 Feb; 18(2):126-35. PubMed ID: 9462740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sequence-specific DNA binding and transcriptional regulation by the promyelocytic leukemia zinc finger protein.
    Li JY; English MA; Ball HJ; Yeyati PL; Waxman S; Licht JD
    J Biol Chem; 1997 Sep; 272(36):22447-55. PubMed ID: 9278395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
    Ruthardt M; Testa U; Nervi C; Ferrucci PF; Grignani F; Puccetti E; Grignani F; Peschle C; Pelicci PG
    Mol Cell Biol; 1997 Aug; 17(8):4859-69. PubMed ID: 9234742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.
    Grignani F; De Matteis S; Nervi C; Tomassoni L; Gelmetti V; Cioce M; Fanelli M; Ruthardt M; Ferrara FF; Zamir I; Seiser C; Grignani F; Lazar MA; Minucci S; Pelicci PG
    Nature; 1998 Feb; 391(6669):815-8. PubMed ID: 9486655
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.
    Melnick A; Carlile G; Ahmad KF; Kiang CL; Corcoran C; Bardwell V; Prive GG; Licht JD
    Mol Cell Biol; 2002 Mar; 22(6):1804-18. PubMed ID: 11865059
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.
    Wong CW; Privalsky ML
    J Biol Chem; 1998 Oct; 273(42):27695-702. PubMed ID: 9765306
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF.
    Dhordain P; Albagli O; Honore N; Guidez F; Lantoine D; Schmid M; The HD; Zelent A; Koken MH
    Oncogene; 2000 Dec; 19(54):6240-50. PubMed ID: 11175338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.
    Puccetti E; Zheng X; Brambilla D; Seshire A; Beissert T; Boehrer S; Nürnberger H; Hoelzer D; Ottmann OG; Nervi C; Ruthardt M
    Cancer Res; 2005 Jul; 65(14):6080-8. PubMed ID: 16024608
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D(3) receptor.
    Ward JO; McConnell MJ; Carlile GW; Pandolfi PP; Licht JD; Freedman LP
    Blood; 2001 Dec; 98(12):3290-300. PubMed ID: 11719366
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha.
    Cheng GX; Zhu XH; Men XQ; Wang L; Huang QH; Jin XL; Xiong SM; Zhu J; Guo WM; Chen JQ; Xu SF; So E; Chan LC; Waxman S; Zelent A; Chen GQ; Dong S; Liu JX; Chen SJ
    Proc Natl Acad Sci U S A; 1999 May; 96(11):6318-23. PubMed ID: 10339585
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interactions of GATA-2 with the promyelocytic leukemia zinc finger (PLZF) protein, its homologue FAZF, and the t(11;17)-generated PLZF-retinoic acid receptor alpha oncoprotein.
    Tsuzuki S; Enver T
    Blood; 2002 May; 99(9):3404-10. PubMed ID: 11964310
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.