BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 18505367)

  • 1. Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd.
    Kubota T; Michigami T; Sakaguchi N; Kokubu C; Suzuki A; Namba N; Sakai N; Nakajima S; Imai K; Ozono K
    J Bone Miner Res; 2008 Oct; 23(10):1661-71. PubMed ID: 18505367
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.
    Li Y; Chen J; Lu W; McCormick LM; Wang J; Bu G
    J Cell Sci; 2005 Nov; 118(Pt 22):5305-14. PubMed ID: 16263759
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.
    Kokubu C; Heinzmann U; Kokubu T; Sakai N; Kubota T; Kawai M; Wahl MB; Galceran J; Grosschedl R; Ozono K; Imai K
    Development; 2004 Nov; 131(21):5469-80. PubMed ID: 15469977
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Osteoblast-targeted expression of Sfrp4 in mice results in low bone mass.
    Nakanishi R; Akiyama H; Kimura H; Otsuki B; Shimizu M; Tsuboyama T; Nakamura T
    J Bone Miner Res; 2008 Feb; 23(2):271-7. PubMed ID: 17907918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased bone formation in mice lacking apolipoprotein E.
    Schilling AF; Schinke T; Münch C; Gebauer M; Niemeier A; Priemel M; Streichert T; Rueger JM; Amling M
    J Bone Miner Res; 2005 Feb; 20(2):274-82. PubMed ID: 15647822
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells.
    Lu W; Liu CC; Thottassery JV; Bu G; Li Y
    Biochemistry; 2010 Jun; 49(22):4635-43. PubMed ID: 20446724
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Cytokines in bone diseases. Wnt signaling and osteoporosis-pseudoglioma syndrome].
    Ozono K
    Clin Calcium; 2010 Oct; 20(10):1520-5. PubMed ID: 20890034
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway.
    Mi K; Johnson GV
    J Cell Biochem; 2005 May; 95(2):328-38. PubMed ID: 15778991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.
    Li Y; Lu W; He X; Bu G
    FEBS Lett; 2006 Oct; 580(22):5423-8. PubMed ID: 16989816
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss.
    Wang L; Liu S; Quarles LD; Spurney RF
    Am J Physiol Endocrinol Metab; 2005 Apr; 288(4):E826-34. PubMed ID: 15585587
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of association of LRP5, LRP6, SOST, DKK1, and CTNNB1 genes with bone mineral density in a Slovenian population.
    Mencej-Bedrac S; Prezelj J; Kocjan T; Komadina R; Marc J
    Calcif Tissue Int; 2009 Dec; 85(6):501-6. PubMed ID: 19898734
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of membrane-bound steel factor results in osteopenia in mice.
    Lotinun S; Evans GL; Turner RT; Oursler MJ
    J Bone Miner Res; 2005 Apr; 20(4):644-52. PubMed ID: 15765184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.
    Okamoto M; Murai J; Yoshikawa H; Tsumaki N
    J Bone Miner Res; 2006 Jul; 21(7):1022-33. PubMed ID: 16813523
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia.
    Li J; Sarosi I; Cattley RC; Pretorius J; Asuncion F; Grisanti M; Morony S; Adamu S; Geng Z; Qiu W; Kostenuik P; Lacey DL; Simonet WS; Bolon B; Qian X; Shalhoub V; Ominsky MS; Zhu Ke H; Li X; Richards WG
    Bone; 2006 Oct; 39(4):754-66. PubMed ID: 16730481
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
    Holmen SL; Giambernardi TA; Zylstra CR; Buckner-Berghuis BD; Resau JH; Hess JF; Glatt V; Bouxsein ML; Ai M; Warman ML; Williams BO
    J Bone Miner Res; 2004 Dec; 19(12):2033-40. PubMed ID: 15537447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass.
    Morvan F; Boulukos K; Clément-Lacroix P; Roman Roman S; Suc-Royer I; Vayssière B; Ammann P; Martin P; Pinho S; Pognonec P; Mollat P; Niehrs C; Baron R; Rawadi G
    J Bone Miner Res; 2006 Jun; 21(6):934-45. PubMed ID: 16753024
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.
    Kelly OG; Pinson KI; Skarnes WC
    Development; 2004 Jun; 131(12):2803-15. PubMed ID: 15142971
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.
    Qiang YW; Barlogie B; Rudikoff S; Shaughnessy JD
    Bone; 2008 Apr; 42(4):669-80. PubMed ID: 18294945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lrp5 and bone formation : A serotonin-dependent pathway.
    Yadav VK; Ducy P
    Ann N Y Acad Sci; 2010 Mar; 1192():103-9. PubMed ID: 20392224
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Melatonin at pharmacologic doses increases bone mass by suppressing resorption through down-regulation of the RANKL-mediated osteoclast formation and activation.
    Koyama H; Nakade O; Takada Y; Kaku T; Lau KH
    J Bone Miner Res; 2002 Jul; 17(7):1219-29. PubMed ID: 12096835
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.