BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 18508156)

  • 1. Renal uptake and metabolism of radiopharmaceuticals derived from peptides and proteins.
    Akizawa H; Uehara T; Arano Y
    Adv Drug Deliv Rev; 2008 Sep; 60(12):1319-28. PubMed ID: 18508156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Strategies to reduce renal radioactivity levels of antibody fragments.
    Arano Y
    Q J Nucl Med; 1998 Dec; 42(4):262-70. PubMed ID: 9973841
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro system to estimate renal brush border enzyme-mediated cleavage of Peptide linkages for designing radiolabeled antibody fragments of low renal radioactivity levels.
    Fujioka Y; Satake S; Uehara T; Mukai T; Akizawa H; Ogawa K; Saji H; Endo K; Arano Y
    Bioconjug Chem; 2005; 16(6):1610-6. PubMed ID: 16287261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and evaluation of [188Re]organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels.
    Uehara T; Koike M; Nakata H; Hanaoka H; Iida Y; Hashimoto K; Akizawa H; Endo K; Arano Y
    Bioconjug Chem; 2007; 18(1):190-8. PubMed ID: 17226973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Renal toxicity of radiolabeled peptides and antibody fragments: mechanisms, impact on radionuclide therapy, and strategies for prevention.
    Vegt E; de Jong M; Wetzels JF; Masereeuw R; Melis M; Oyen WJ; Gotthardt M; Boerman OC
    J Nucl Med; 2010 Jul; 51(7):1049-58. PubMed ID: 20554737
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Renal handling of proteins and peptides.
    Carone FA
    Ann Clin Lab Sci; 1978; 8(4):287-94. PubMed ID: 686646
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reducing the renal uptake of radiolabeled antibody fragments and peptides for diagnosis and therapy: present status, future prospects and limitations.
    Behr TM; Goldenberg DM; Becker W
    Eur J Nucl Med; 1998 Feb; 25(2):201-12. PubMed ID: 9473271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preferential Cleavage of a Tripeptide Linkage by Enzymes on Renal Brush Border Membrane To Reduce Renal Radioactivity Levels of Radiolabeled Antibody Fragments.
    Suzuki C; Uehara T; Kanazawa N; Wada S; Suzuki H; Arano Y
    J Med Chem; 2018 Jun; 61(12):5257-5268. PubMed ID: 29869881
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pretargeted versus directly targeted radioimmunotherapy combined with anti-CD20 antibody consolidation therapy of non-Hodgkin lymphoma.
    Sharkey RM; Karacay H; Johnson CR; Litwin S; Rossi EA; McBride WJ; Chang CH; Goldenberg DM
    J Nucl Med; 2009 Mar; 50(3):444-53. PubMed ID: 19223402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Renal brush border strategy: A developing procedure to reduce renal radioactivity levels of radiolabeled polypeptides.
    Arano Y
    Nucl Med Biol; 2021 Jan; 92():149-155. PubMed ID: 32169305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity].
    Mukai T; Fujioka Y; Arano Y; Saji H
    Yakugaku Zasshi; 2003 Aug; 123(8):647-52. PubMed ID: 12931660
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual MVK cleavable linkers effectively reduce renal retention of
    Valpreda G; Trachsel B; Vogel V; Schibli R; Mu L; Behe M
    Bioorg Med Chem; 2022 Nov; 73():117040. PubMed ID: 36202066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Altering pharmacokinetics of radiolabeled antibodies by the interposition of metabolizable linkages. Metabolizable linkers and pharmacokinetics of monoclonal antibodies.
    Akizawa H; Arano Y
    Q J Nucl Med; 2002 Sep; 46(3):206-23. PubMed ID: 12134137
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proceedings: The bovine protease inhibitor as a tool for studying the renal reabsorption of peptides.
    Just M; Habermann E
    Naunyn Schmiedebergs Arch Pharmacol; 1974; 282(Suppl):suppl 282:R43. PubMed ID: 4276578
    [No Abstract]   [Full Text] [Related]  

  • 15. Cleavable linkers to enhance selectivity of antibody-targeted therapy of cancer.
    Kukis DL; Novak-Hofer I; DeNardo SJ
    Cancer Biother Radiopharm; 2001 Dec; 16(6):457-67. PubMed ID: 11789023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Receptor-mediated tumor targeting with radiopeptides. Part 1. General principles and methods.
    Eberle AN; Mild G
    J Recept Signal Transduct Res; 2009; 29(1):1-37. PubMed ID: 19519167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduction of the Renal Radioactivity of
    Suzuki H; Araki M; Tatsugi K; Ichinohe K; Uehara T; Arano Y
    J Med Chem; 2023 Jul; 66(13):8600-8613. PubMed ID: 37322876
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypertension-mediated albuminuria is associated with reduced lysosomal activity in the kidney and the heart.
    Hilliard LM; Russo LM; Comper WD
    Am J Nephrol; 2009; 29(5):454-64. PubMed ID: 19023196
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specific labeling with potent radiolabels alters the uptake of cell-penetrating peptides.
    Walther C; Ott I; Gust R; Neundorf I
    Biopolymers; 2009; 92(5):445-51. PubMed ID: 19399852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis.
    Brandi L
    Dan Med Bull; 2008 Nov; 55(4):186-210. PubMed ID: 19232159
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.