146 related articles for article (PubMed ID: 1851845)
1. Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity.
Huang FC; Galemmo RA; Poli GB; Learn KS; Morrissette MM; Johnson WH; Dankulich WP; Campbell HF; Carnathan GW; VanInwegen RG
J Med Chem; 1991 May; 34(5):1704-7. PubMed ID: 1851845
[TBL] [Abstract][Full Text] [Related]
2. Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity.
Huang FC; Galemmo RA; Johnson WH; Poli GB; Morrissette MM; Mencel JJ; Warus JD; Campbell HF; Nuss GW; Carnathan GW
J Med Chem; 1990 Apr; 33(4):1194-200. PubMed ID: 2157010
[TBL] [Abstract][Full Text] [Related]
3. The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency.
Galemmo RA; Johnson WH; Learn KS; Lee TD; Huang FC; Campbell HF; Youssefyeh R; O'Rourke SV; Schuessler G; Sweeney DM
J Med Chem; 1990 Oct; 33(10):2828-41. PubMed ID: 2170649
[TBL] [Abstract][Full Text] [Related]
4. Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 1. Initial structure-activity relationships.
Youssefyeh RD; Magnien E; Lee TD; Chan WK; Lin CJ; Galemmo RA; Johnson WH; Tan J; Campbell HF; Huang FC
J Med Chem; 1990 Apr; 33(4):1186-94. PubMed ID: 2157009
[TBL] [Abstract][Full Text] [Related]
5. Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of agonist-receptor binding affinity states.
O'Sullivan BP; Mong S
Mol Pharmacol; 1989 Jun; 35(6):795-802. PubMed ID: 2543913
[TBL] [Abstract][Full Text] [Related]
6. Characterization of the leukotriene D4 receptor in hyperreactive rat lung.
Metters KM; Frey EA; Ford-Hutchinson AW
Eur J Pharmacol; 1991 Feb; 194(1):51-61. PubMed ID: 1647964
[TBL] [Abstract][Full Text] [Related]
7. Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl] [[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist.
Gauthier JY; Jones T; Champion E; Charette L; Dehaven R; Ford-Hutchinson AW; Hoogsteen K; Lord A; Masson P; Piechuta H
J Med Chem; 1990 Oct; 33(10):2841-5. PubMed ID: 2170650
[TBL] [Abstract][Full Text] [Related]
8. N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
Musser JH; Kreft AF; Bender RH; Kubrak DM; Grimes D; Carlson RP; Hand JM; Chang J
J Med Chem; 1990 Jan; 33(1):240-5. PubMed ID: 2104935
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological characterization using selected antagonists of the leukotriene receptors mediating contraction of guinea-pig trachea.
Hand JM; Schwalm SF; Englebach IM; Auen MA; Musser JH; Kreft AF
Prostaglandins; 1989 Feb; 37(2):181-91. PubMed ID: 2543033
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of 3H-leukotriene D4 binding to guinea pig lung receptors by the novel leukotriene antagonist ICI 198,615.
Aharony D; Falcone RC; Krell RD
J Pharmacol Exp Ther; 1987 Dec; 243(3):921-6. PubMed ID: 2826761
[TBL] [Abstract][Full Text] [Related]
11. Characterization of the leukotriene D4 receptor in dimethylsulphoxide-differentiated U937 cells: comparison with the leukotriene D4 receptor in human lung and guinea-pig lung.
Frey EA; Nicholson DW; Metters KM
Eur J Pharmacol; 1993 Feb; 244(3):239-50. PubMed ID: 8384568
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.
Musser JH; Kubrak DM; Chang J; Lewis AJ
J Med Chem; 1986 Aug; 29(8):1429-35. PubMed ID: 3090264
[TBL] [Abstract][Full Text] [Related]
13. Post soluble binding to the leukotriene D4 receptor from guinea pig lung membranes.
Mong S; Sarau HM
Mol Pharmacol; 1990 Jan; 37(1):60-4. PubMed ID: 2153909
[TBL] [Abstract][Full Text] [Related]
14. Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (+-)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3- (dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid.
Zamboni R; Belley M; Champion E; Charette L; DeHaven R; Frenette R; Gauthier JY; Jones TR; Leger S; Masson P
J Med Chem; 1992 Oct; 35(21):3832-44. PubMed ID: 1331447
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationships of carboxyflavones as structurally rigid CysLT1 (LTD4) receptor antagonists.
Zwaagstra ME; Timmerman H; van de Stolpe AC; de Kanter FJ; Tamura M; Wada Y; Zhang MQ
J Med Chem; 1998 Apr; 41(9):1428-38. PubMed ID: 9554876
[TBL] [Abstract][Full Text] [Related]
16. Competition of leukotrienes and ICI-198,615 for [3H]LTD4 binding sites in guinea pig lung membranes suggests the involvement of two LTD4 receptor subtypes.
Shirley JT; Cheng JB
J Pharmacol Exp Ther; 1991 Aug; 258(2):531-6. PubMed ID: 1650832
[TBL] [Abstract][Full Text] [Related]
17. SKF 104353, a high affinity antagonist for human and guinea pig lung leukotriene D4 receptor, blocked phosphatidylinositol metabolism and thromboxane synthesis induced by leukotriene D4.
Mong S; Wu HL; Miller J; Hall RF; Gleason JG; Crooke ST
Mol Pharmacol; 1987 Aug; 32(1):223-9. PubMed ID: 3039338
[TBL] [Abstract][Full Text] [Related]
18. Hydroxyacetophenone-derived antagonists of the peptidoleukotrienes.
Brown FJ; Bernstein PR; Cronk LA; Dosset DL; Hebbel KC; Maduskuie TP; Shapiro HS; Vacek EP; Yee YK; Willard AK
J Med Chem; 1989 Apr; 32(4):807-26. PubMed ID: 2704027
[TBL] [Abstract][Full Text] [Related]
19. Assessment of leukotriene D4 receptor antagonists.
Aharony D
Methods Enzymol; 1990; 187():414-21. PubMed ID: 2172739
[TBL] [Abstract][Full Text] [Related]
20. The preclinical pharmacology of ICI 204,219. A peptide leukotriene antagonist.
Krell RD; Aharony D; Buckner CK; Keith RA; Kusner EJ; Snyder DW; Bernstein PR; Matassa VG; Yee YK; Brown FJ
Am Rev Respir Dis; 1990 Apr; 141(4 Pt 1):978-87. PubMed ID: 2158259
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
