These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 18523102)

  • 21. Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding.
    Kosinska U; Carnrot C; Sandrini MP; Clausen AR; Wang L; Piskur J; Eriksson S; Eklund H
    FEBS J; 2007 Feb; 274(3):727-37. PubMed ID: 17288553
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.
    Darnowski JW; Goulette FA
    Biochem Pharmacol; 1994 Nov; 48(9):1797-805. PubMed ID: 7980649
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.
    Ostermann N; Segura-Peña D; Meier C; Veit T; Monnerjahn C; Konrad M; Lavie A
    Biochemistry; 2003 Mar; 42(9):2568-77. PubMed ID: 12614151
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
    Balzarini J; Aquaro S; Knispel T; Rampazzo C; Bianchi V; Perno CF; De Clercq E; Meier C
    Mol Pharmacol; 2000 Nov; 58(5):928-35. PubMed ID: 11040039
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutations distal to the substrate site can affect varicella zoster virus thymidine kinase activity: implications for drug design.
    El Omari K; Liekens S; Bird LE; Balzarini J; Stammers DK
    Mol Pharmacol; 2006 Jun; 69(6):1891-6. PubMed ID: 16556772
    [TBL] [Abstract][Full Text] [Related]  

  • 26. An optimized thymidylate kinase assay, based on enzymatically synthesized 5-[125I]iododeoxyuridine monophosphate and its application to an immunological study of herpes simplex virus thymidine-thymidylate kinases.
    Karlström AR; Gronowitz JS
    Anal Biochem; 1987 May; 162(2):500-10. PubMed ID: 3037945
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
    Topalis D; Pradère U; Roy V; Caillat C; Azzouzi A; Broggi J; Snoeck R; Andrei G; Lin J; Eriksson S; Alexandre JA; El-Amri C; Deville-Bonne D; Meyer P; Balzarini J; Agrofoglio LA
    J Med Chem; 2011 Jan; 54(1):222-32. PubMed ID: 21128666
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides.
    Munch-Petersen B; Cloos L; Tyrsted G; Eriksson S
    J Biol Chem; 1991 May; 266(14):9032-8. PubMed ID: 2026611
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Regulation of the activation of fluorodeoxyuridine by substrate competition and feedback inhibition in 647V cells.
    Vazquez-Padua MA; Risueno C; Fischer PH
    Cancer Res; 1989 Feb; 49(3):618-24. PubMed ID: 2521299
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Vanheusden V; Munier-Lehmann H; Froeyen M; Dugué L; Heyerick A; De Keukeleire D; Pochet S; Busson R; Herdewijn P; Van Calenbergh S
    J Med Chem; 2003 Aug; 46(18):3811-21. PubMed ID: 12930144
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Expression of human mitochondrial thymidine kinase in Escherichia coli: correlation between the enzymatic activity of pyrimidine nucleoside analogues and their inhibitory effect on bacterial growth.
    Wang J; Su C; Neuhard J; Eriksson S
    Biochem Pharmacol; 2000 Jun; 59(12):1583-8. PubMed ID: 10799656
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
    Palomino E; Meltsner BR; Kessel D; Horwitz JP
    J Med Chem; 1990 Jan; 33(1):258-63. PubMed ID: 2153206
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of Streptococcus pneumoniae thymidylate kinase: steady-state kinetics of the forward reaction and isothermal titration calorimetry.
    Petit CM; Koretke KK
    Biochem J; 2002 May; 363(Pt 3):825-31. PubMed ID: 11964185
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A novel viral thymidylate kinase with dual kinase activity.
    Guevara-Hernandez E; Arvizu-Flores AA; Lugo-Sanchez ME; Velazquez-Contreras EF; Castillo-Yañez FJ; Brieba LG; Sotelo-Mundo RR
    J Bioenerg Biomembr; 2015 Oct; 47(5):431-40. PubMed ID: 26315341
    [TBL] [Abstract][Full Text] [Related]  

  • 35. cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system.
    Meier C; Lorey M; De Clercq E; Balzarini J
    J Med Chem; 1998 Apr; 41(9):1417-27. PubMed ID: 9554875
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 5-Substituted N(4)-hydroxy-2'-deoxycytidines and their 5'-monophosphates: synthesis, conformation, interaction with tumor thymidylate synthase, and in vitro antitumor activity.
    Felczak K; Miazga A; Poznański J; Bretner M; Kulikowski T; Dzik JM; Gołos B; Zieliński Z; Cieśla J; Rode W
    J Med Chem; 2000 Nov; 43(24):4647-56. PubMed ID: 11101356
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.
    Hsu CH; Hu R; Dutschman GE; Yang G; Krishnan P; Tanaka H; Baba M; Cheng YC
    Antimicrob Agents Chemother; 2007 May; 51(5):1687-93. PubMed ID: 17353236
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Characterization of pyrimidine nucleoside monophosphokinase in normal and malignant tissues.
    Arima T; Akiyoshi H; Fujii S
    Cancer Res; 1977 Jun; 37(6):1593-7. PubMed ID: 192455
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major.
    Timm J; Bosch-Navarrete C; Recio E; Nettleship JE; Rada H; González-Pacanowska D; Wilson KS
    PLoS Negl Trop Dis; 2015 May; 9(5):e0003781. PubMed ID: 25978379
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation.
    Lavie A; Konrad M; Brundiers R; Goody RS; Schlichting I; Reinstein J
    Biochemistry; 1998 Mar; 37(11):3677-86. PubMed ID: 9521686
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.