These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 18524779)

  • 1. Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis.
    Mi L; Xiao Z; Hood BL; Dakshanamurthy S; Wang X; Govind S; Conrads TP; Veenstra TD; Chung FL
    J Biol Chem; 2008 Aug; 283(32):22136-46. PubMed ID: 18524779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteomic analysis of covalent modifications of tubulins by isothiocyanates.
    Xiao Z; Mi L; Chung FL; Veenstra TD
    J Nutr; 2012 Jul; 142(7):1377S-81S. PubMed ID: 22649267
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.
    Mi L; Wang X; Govind S; Hood BL; Veenstra TD; Conrads TP; Saha DT; Goldman R; Chung FL
    Cancer Res; 2007 Jul; 67(13):6409-16. PubMed ID: 17616701
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes.
    Mi L; Gan N; Cheema A; Dakshanamurthy S; Wang X; Yang DCH; Chung FL
    J Biol Chem; 2009 Jun; 284(25):17039-17051. PubMed ID: 19339240
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.
    Mi L; Chung FL
    Nutr Cancer; 2008; 60 Suppl 1():12-20. PubMed ID: 19003576
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of potential protein targets of isothiocyanates by proteomics.
    Mi L; Hood BL; Stewart NA; Xiao Z; Govind S; Wang X; Conrads TP; Veenstra TD; Chung FL
    Chem Res Toxicol; 2011 Oct; 24(10):1735-43. PubMed ID: 21838287
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.
    Mi L; Gan N; Chung FL
    Carcinogenesis; 2011 Feb; 32(2):216-23. PubMed ID: 21109604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
    Yang YM; Conaway CC; Chiao JW; Wang CX; Amin S; Whysner J; Dai W; Reinhardt J; Chung FL
    Cancer Res; 2002 Jan; 62(1):2-7. PubMed ID: 11782348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New biomarkers for monitoring the levels of isothiocyanates in humans.
    Kumar A; Sabbioni G
    Chem Res Toxicol; 2010 Apr; 23(4):756-65. PubMed ID: 20131755
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines.
    Jakubikova J; Bao Y; Sedlak J
    Anticancer Res; 2005; 25(5):3375-86. PubMed ID: 16101152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selected isothiocyanates rapidly induce growth inhibition of cancer cells.
    Zhang Y; Tang L; Gonzalez V
    Mol Cancer Ther; 2003 Oct; 2(10):1045-52. PubMed ID: 14578469
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers.
    Soundararajan P; Kim JS
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30445746
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells.
    Sakao K; Vyas AR; Chinni SR; Amjad AI; Parikh R; Singh SV
    Cancer Prev Res (Phila); 2015 May; 8(5):365-74. PubMed ID: 25712054
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sulforaphane metabolites cause apoptosis via microtubule disruption in cancer.
    Zhou Y; Yang G; Tian H; Hu Y; Wu S; Geng Y; Lin K; Wu W
    Endocr Relat Cancer; 2018 Mar; 25(3):255-268. PubMed ID: 29431641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Computational and biochemical studies of isothiocyanates as inhibitors of proteasomal cysteine deubiquitinases in human cancer cells.
    Ahmed ZSO; Li X; Li F; Cheaito HA; Patel K; Mosallam EM; Elbargeesy GAEH; Dou QP
    J Cell Biochem; 2018 Nov; 119(11):9006-9016. PubMed ID: 30015387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells.
    Liu HJ; Wang L; Kang L; Du J; Li S; Cui HX
    Cell Physiol Biochem; 2018; 51(2):528-542. PubMed ID: 30458452
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells.
    Tang L; Zhang Y
    Mol Cancer Ther; 2005 Aug; 4(8):1250-9. PubMed ID: 16093441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteomic identification of binding targets of isothiocyanates: A perspective on techniques.
    Mi L; Xiao Z; Veenstra TD; Chung FL
    J Proteomics; 2011 Jun; 74(7):1036-44. PubMed ID: 21555001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL; Huang AC; Yang JS; Liao CL; Lu HF; Chou ST; Ma CY; Hsia TC; Ko YC; Chung JG
    J Orthop Res; 2011 Aug; 29(8):1199-209. PubMed ID: 21374707
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell death induction by isothiocyanates and their underlying molecular mechanisms.
    Nakamura Y; Miyoshi N
    Biofactors; 2006; 26(2):123-34. PubMed ID: 16823098
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.