101 related articles for article (PubMed ID: 18533112)
1. Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells.
Shama J; Garcia-Medina R; Pouysségur J; Vial E
Biochem Biophys Res Commun; 2008 Aug; 372(4):845-9. PubMed ID: 18533112
[TBL] [Abstract][Full Text] [Related]
2. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
Gailhouste L; Ezan F; Bessard A; Frémin C; Rageul J; Langouët S; Baffet G
Int J Cancer; 2010 Mar; 126(6):1367-77. PubMed ID: 19816936
[TBL] [Abstract][Full Text] [Related]
3. Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1).
Dwivedi Y; Rizavi HS; Zhang H; Roberts RC; Conley RR; Pandey GN
Int J Neuropsychopharmacol; 2009 Nov; 12(10):1337-54. PubMed ID: 19835659
[TBL] [Abstract][Full Text] [Related]
4. Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.
Shin J; Yang J; Lee JC; Baek KH
Cell Signal; 2013 Dec; 25(12):2540-7. PubMed ID: 23993963
[TBL] [Abstract][Full Text] [Related]
5. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
Marzec M; Kasprzycka M; Liu X; Raghunath PN; Wlodarski P; Wasik MA
Oncogene; 2007 Feb; 26(6):813-21. PubMed ID: 16909118
[TBL] [Abstract][Full Text] [Related]
6. ERK1/2 can feedback-regulate cellular MEK1/2 levels.
Hong SK; Wu PK; Karkhanis M; Park JI
Cell Signal; 2015 Oct; 27(10):1939-48. PubMed ID: 26163823
[TBL] [Abstract][Full Text] [Related]
7. MAP kinase: it's been longer than fifteen minutes.
Sturgill TW
Biochem Biophys Res Commun; 2008 Jun; 371(1):1-4. PubMed ID: 18406346
[TBL] [Abstract][Full Text] [Related]
8. Ribonucleotide reductase small subunit p53R2 suppresses MEK-ERK activity by binding to ERK kinase 2.
Piao C; Jin M; Kim HB; Lee SM; Amatya PN; Hyun JW; Chang IY; You HJ
Oncogene; 2009 May; 28(21):2173-84. PubMed ID: 19398949
[TBL] [Abstract][Full Text] [Related]
9. Sef downregulation by Ras causes MEK1/2 to become aberrantly nuclear localized leading to polyploidy and neoplastic transformation.
Duhamel S; Hébert J; Gaboury L; Bouchard A; Simon R; Sauter G; Basik M; Meloche S
Cancer Res; 2012 Feb; 72(3):626-35. PubMed ID: 22298595
[TBL] [Abstract][Full Text] [Related]
10. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
[TBL] [Abstract][Full Text] [Related]
11. The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
Yamashita S; Tai P; Charron J; Ko C; Ascoli M
Mol Endocrinol; 2011 Jul; 25(7):1211-22. PubMed ID: 21527500
[TBL] [Abstract][Full Text] [Related]
12. MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.
Skarpen E; Flinder LI; Rosseland CM; Orstavik S; Wierød L; Oksvold MP; Skålhegg BS; Huitfeldt HS
FASEB J; 2008 Feb; 22(2):466-76. PubMed ID: 17928366
[TBL] [Abstract][Full Text] [Related]
13. A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.
Catalanotti F; Reyes G; Jesenberger V; Galabova-Kovacs G; de Matos Simoes R; Carugo O; Baccarini M
Nat Struct Mol Biol; 2009 Mar; 16(3):294-303. PubMed ID: 19219045
[TBL] [Abstract][Full Text] [Related]
14. Identification of novel point mutations in ERK2 that selectively disrupt binding to MEK1.
Robinson FL; Whitehurst AW; Raman M; Cobb MH
J Biol Chem; 2002 Apr; 277(17):14844-52. PubMed ID: 11823456
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
Menendez JA; Vellon L; Colomer R; Lupu R
Int J Cancer; 2005 May; 115(1):19-35. PubMed ID: 15657900
[TBL] [Abstract][Full Text] [Related]
16. Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth.
Sanna B; Bueno OF; Dai YS; Wilkins BJ; Molkentin JD
Mol Cell Biol; 2005 Feb; 25(3):865-78. PubMed ID: 15657416
[TBL] [Abstract][Full Text] [Related]
17. MEK ablation in MCF-7 cells blocks DNA synthesis induced by serum, but not by estradiol or growth factors.
Estes NR; Thottassery JV; Westbrook L; Kern FG
Int J Oncol; 2006 Dec; 29(6):1573-80. PubMed ID: 17088999
[TBL] [Abstract][Full Text] [Related]
18. ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines.
Radtke S; Milanovic M; Rossé C; De Rycker M; Lachmann S; Hibbert A; Kermorgant S; Parker PJ
J Cell Sci; 2013 Jun; 126(Pt 11):2381-91. PubMed ID: 23549785
[TBL] [Abstract][Full Text] [Related]
19. Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
Aoidi R; Maltais A; Charron J
Sci Signal; 2016 Jan; 9(412):ra9. PubMed ID: 26814233
[TBL] [Abstract][Full Text] [Related]
20. A bidirectional "alpha(v)beta(3) integrin-ERK1/ERK2 MAPK" connection regulates the proliferation of breast cancer cells.
Vellon L; Menendez JA; Lupu R
Mol Carcinog; 2006 Oct; 45(10):795-804. PubMed ID: 16705745
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
