BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1126 related articles for article (PubMed ID: 18533686)

  • 1. Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae.
    Qian J; Khandogin J; West AH; Cook PF
    Biochemistry; 2008 Jul; 47(26):6851-8. PubMed ID: 18533686
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae.
    Qian J; West AH; Cook PF
    Biochemistry; 2006 Oct; 45(39):12136-43. PubMed ID: 17002313
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalytic mechanism of hamster arylamine N-acetyltransferase 2.
    Wang H; Liu L; Hanna PE; Wagner CR
    Biochemistry; 2005 Aug; 44(33):11295-306. PubMed ID: 16101314
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
    Wang H; Vath GM; Gleason KJ; Hanna PE; Wagner CR
    Biochemistry; 2004 Jun; 43(25):8234-46. PubMed ID: 15209520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
    Kratzer R; Kavanagh KL; Wilson DK; Nidetzky B
    Biochemistry; 2004 May; 43(17):4944-54. PubMed ID: 15109252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
    Andi B; West AH; Cook PF
    Biochemistry; 2004 Sep; 43(37):11790-5. PubMed ID: 15362863
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
    Karsten WE; Liu D; Rao GS; Harris BG; Cook PF
    Biochemistry; 2005 Mar; 44(9):3626-35. PubMed ID: 15736972
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Catalytic mechanism of SHCHC synthase in the menaquinone biosynthesis of Escherichia coli: identification and mutational analysis of the active site residues.
    Jiang M; Chen X; Wu XH; Chen M; Wu YD; Guo Z
    Biochemistry; 2009 Jul; 48(29):6921-31. PubMed ID: 19545176
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
    Tai CH; Yoon MY; Kim SK; Rege VD; Nalabolu SR; Kredich NM; Schnackerz KD; Cook PF
    Biochemistry; 1998 Jul; 37(30):10597-604. PubMed ID: 9692949
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from Proteus vulgaris.
    Demidkina TV; Zakomirdina LN; Kulikova VV; Dementieva IS; Faleev NG; Ronda L; Mozzarelli A; Gollnick PD; Phillips RS
    Biochemistry; 2003 Sep; 42(38):11161-9. PubMed ID: 14503866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proton donor in yeast pyruvate kinase: chemical and kinetic properties of the active site Thr 298 to Cys mutant.
    Susan-Resiga D; Nowak T
    Biochemistry; 2004 Dec; 43(48):15230-45. PubMed ID: 15568816
    [TBL] [Abstract][Full Text] [Related]  

  • 12. On the catalytic role of the conserved active site residue His466 of choline oxidase.
    Ghanem M; Gadda G
    Biochemistry; 2005 Jan; 44(3):893-904. PubMed ID: 15654745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
    Bobyk KD; Kim SG; Kumar VP; Kim SK; West AH; Cook PF
    Arch Biochem Biophys; 2011 Sep; 513(2):71-80. PubMed ID: 21798231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of 3-hydroxy-3-methylglutaryl-coenzyme A lyase arginine-41 as a catalytic residue: use of acetyldithio-coenzyme A to monitor product enolization.
    Tuinstra RL; Wang CZ; Mitchell GA; Miziorko HM
    Biochemistry; 2004 May; 43(18):5287-95. PubMed ID: 15122894
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolutionary conservation of enzymatic catalysis: quantitative comparison of the effects of mutation of aligned residues in Saccharomyces cerevisiae and Escherichia coli inorganic pyrophosphatases on enzymatic activity.
    Pohjanjoki P; Lahti R; Goldman A; Cooperman BS
    Biochemistry; 1998 Feb; 37(7):1754-61. PubMed ID: 9485300
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for the interaction of avian 3-hydroxy-3-methylglutaryl-CoA synthase histidine 264 with acetoacetyl-CoA.
    Misra I; Miziorko HM
    Biochemistry; 1996 Jul; 35(29):9610-6. PubMed ID: 8755743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Limited proteolysis and X-ray crystallography reveal the origin of substrate specificity and of the rate-limiting product release during oxidation of D-amino acids catalyzed by mammalian D-amino acid oxidase.
    Vanoni MA; Cosma A; Mazzeo D; Mattevi A; Todone F; Curti B
    Biochemistry; 1997 May; 36(19):5624-32. PubMed ID: 9153402
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetic and spectroscopic characterization of the H178A methionyl aminopeptidase from Escherichia coli.
    Copik AJ; Swierczek SI; Lowther WT; D'souza VM; Matthews BW; Holz RC
    Biochemistry; 2003 May; 42(20):6283-92. PubMed ID: 12755633
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stabilization of the second oxyanion intermediate by 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase of the menaquinone pathway: spectroscopic evidence of the involvement of a conserved aspartic acid.
    Chen M; Jiang M; Sun Y; Guo ZF; Guo Z
    Biochemistry; 2011 Jul; 50(26):5893-904. PubMed ID: 21627110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The roles of active-site residues in the catalytic mechanism of trans-3-chloroacrylic acid dehalogenase: a kinetic, NMR, and mutational analysis.
    Azurmendi HF; Wang SC; Massiah MA; Poelarends GJ; Whitman CP; Mildvan AS
    Biochemistry; 2004 Apr; 43(14):4082-91. PubMed ID: 15065850
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 57.