208 related articles for article (PubMed ID: 18534183)
1. TRAP-LIG, a modified telomere repeat amplification protocol assay to quantitate telomerase inhibition by small molecules.
Reed J; Gunaratnam M; Beltran M; Reszka AP; Vilar R; Neidle S
Anal Biochem; 2008 Sep; 380(1):99-105. PubMed ID: 18534183
[TBL] [Abstract][Full Text] [Related]
2. Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay.
Gomez D; Mergny JL; Riou JF
Cancer Res; 2002 Jun; 62(12):3365-8. PubMed ID: 12067975
[TBL] [Abstract][Full Text] [Related]
3. Detection of telomerase activity in cultured cells and tumor tissue of lung carcinoma by modified telomeric repeat amplification protocol.
Liu Y; Wu BQ; Zhong HH; Xu ML; Fang WG
Pathol Int; 2010 May; 60(5):386-94. PubMed ID: 20518889
[TBL] [Abstract][Full Text] [Related]
4. Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
Bhattacharya S; Chaudhuri P; Jain AK; Paul A
Bioconjug Chem; 2010 Jul; 21(7):1148-59. PubMed ID: 20536245
[TBL] [Abstract][Full Text] [Related]
5. Nonradioactive detection of telomerase activity using the telomeric repeat amplification protocol.
Herbert BS; Hochreiter AE; Wright WE; Shay JW
Nat Protoc; 2006; 1(3):1583-90. PubMed ID: 17406450
[TBL] [Abstract][Full Text] [Related]
6. 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.
Zhang WJ; Ou TM; Lu YJ; Huang YY; Wu WB; Huang ZS; Zhou JL; Wong KY; Gu LQ
Bioorg Med Chem; 2007 Aug; 15(16):5493-501. PubMed ID: 17574421
[TBL] [Abstract][Full Text] [Related]
7. Porphyrin derivatives for telomere binding and telomerase inhibition.
Dixon IM; Lopez F; Estève JP; Tejera AM; Blasco MA; Pratviel G; Meunier B
Chembiochem; 2005 Jan; 6(1):123-32. PubMed ID: 15551357
[TBL] [Abstract][Full Text] [Related]
8. Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands.
Chen CY; Wang Q; Liu JQ; Hao YH; Tan Z
J Am Chem Soc; 2011 Sep; 133(38):15036-44. PubMed ID: 21846102
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands.
Laronze-Cochard M; Kim YM; Brassart B; Riou JF; Laronze JY; Sapi J
Eur J Med Chem; 2009 Oct; 44(10):3880-8. PubMed ID: 19467742
[TBL] [Abstract][Full Text] [Related]
10. An evaluation cascade for G-quadruplex telomere targeting agents in human cancer cells.
Gunaratnam M; Neidle S
Methods Mol Biol; 2010; 613():303-13. PubMed ID: 19997892
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors.
Schultes CM; Guyen B; Cuesta J; Neidle S
Bioorg Med Chem Lett; 2004 Aug; 14(16):4347-51. PubMed ID: 15261300
[TBL] [Abstract][Full Text] [Related]
12. Real-time telomeric repeat amplification protocol using the duplex scorpion and two reverse primers system: the high sensitive and accurate method for quantification of telomerase activity.
Huang YP; Liu ZS; Tang H; Liu M; Li X
Clin Chim Acta; 2006 Oct; 372(1-2):112-9. PubMed ID: 16714009
[TBL] [Abstract][Full Text] [Related]
13. Microarray TRAP--a high-throughput assay to quantitate telomerase activity.
Heller-Uszynska K; Kilian A
Biochem Biophys Res Commun; 2004 Oct; 323(2):465-72. PubMed ID: 15369774
[TBL] [Abstract][Full Text] [Related]
14. Targeting telomeres and telomerase.
De Cian A; Lacroix L; Douarre C; Temime-Smaali N; Trentesaux C; Riou JF; Mergny JL
Biochimie; 2008 Jan; 90(1):131-55. PubMed ID: 17822826
[TBL] [Abstract][Full Text] [Related]
15. Telomeric repeat amplification protocol: measuring the activity of the telomerase.
Xin H
Methods Mol Biol; 2011; 735():107-11. PubMed ID: 21461815
[TBL] [Abstract][Full Text] [Related]
16. NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.
Fedoroff OY; Salazar M; Han H; Chemeris VV; Kerwin SM; Hurley LH
Biochemistry; 1998 Sep; 37(36):12367-74. PubMed ID: 9730808
[TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells.
Maji B; Kumar K; Kaulage M; Muniyappa K; Bhattacharya S
J Med Chem; 2014 Aug; 57(16):6973-88. PubMed ID: 25062468
[TBL] [Abstract][Full Text] [Related]
18. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents.
Cookson JC; Dai F; Smith V; Heald RA; Laughton CA; Stevens MF; Burger AM
Mol Pharmacol; 2005 Dec; 68(6):1551-8. PubMed ID: 16150933
[TBL] [Abstract][Full Text] [Related]
19. Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells.
Binz N; Shalaby T; Rivera P; Shin-ya K; Grotzer MA
Eur J Cancer; 2005 Dec; 41(18):2873-81. PubMed ID: 16253503
[TBL] [Abstract][Full Text] [Related]
20. In vitro and in vivo inhibition of telomerase activity from Chinese hamster V79 cells.
Pandit B; Bhattacharyya NP
Indian J Biochem Biophys; 2001; 38(1-2):42-7. PubMed ID: 11563329
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
