BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 18536016)

  • 1. Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: bioinformatics-based predictions generate true positives and false negatives.
    Meinhardt S; Swint-Kruse L
    Proteins; 2008 Dec; 73(4):941-57. PubMed ID: 18536016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue.
    Zhan H; Taraban M; Trewhella J; Swint-Kruse L
    Biochemistry; 2008 Aug; 47(31):8058-69. PubMed ID: 18616293
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional consequences of exchanging domains between LacI and PurR are mediated by the intervening linker sequence.
    Tungtur S; Egan SM; Swint-Kruse L
    Proteins; 2007 Jul; 68(1):375-88. PubMed ID: 17436321
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparing the functional roles of nonconserved sequence positions in homologous transcription repressors: implications for sequence/function analyses.
    Tungtur S; Meinhardt S; Swint-Kruse L
    J Mol Biol; 2010 Jan; 395(4):785-802. PubMed ID: 19818797
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression.
    Meinhardt S; Manley MW; Becker NA; Hessman JA; Maher LJ; Swint-Kruse L
    Nucleic Acids Res; 2012 Nov; 40(21):11139-54. PubMed ID: 22965134
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fine-tuning function: correlation of hinge domain interactions with functional distinctions between LacI and PurR.
    Swint-Kruse L; Larson C; Pettitt BM; Matthews KS
    Protein Sci; 2002 Apr; 11(4):778-94. PubMed ID: 11910022
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Parallel evolution of ligand specificity between LacI/GalR family repressors and periplasmic sugar-binding proteins.
    Fukami-Kobayashi K; Tateno Y; Nishikawa K
    Mol Biol Evol; 2003 Feb; 20(2):267-77. PubMed ID: 12598694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
    Swint-Kruse L; Elam CR; Lin JW; Wycuff DR; Shive Matthews K
    Protein Sci; 2001 Feb; 10(2):262-76. PubMed ID: 11266612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence.
    Markiewicz P; Kleina LG; Cruz C; Ehret S; Miller JH
    J Mol Biol; 1994 Jul; 240(5):421-33. PubMed ID: 8046748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functionally important positions can comprise the majority of a protein's architecture.
    Tungtur S; Parente DJ; Swint-Kruse L
    Proteins; 2011 May; 79(5):1589-608. PubMed ID: 21374721
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allostery in the LacI/GalR family: variations on a theme.
    Swint-Kruse L; Matthews KS
    Curr Opin Microbiol; 2009 Apr; 12(2):129-37. PubMed ID: 19269243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Operator search by mutant Lac repressors.
    Barker A; Fickert R; Oehler S; Müller-hill B
    J Mol Biol; 1998 May; 278(3):549-58. PubMed ID: 9600838
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AlloRep: A Repository of Sequence, Structural and Mutagenesis Data for the LacI/GalR Transcription Regulators.
    Sousa FL; Parente DJ; Shis DL; Hessman JA; Chazelle A; Bennett MR; Teichmann SA; Swint-Kruse L
    J Mol Biol; 2016 Feb; 428(4):671-678. PubMed ID: 26410588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain.
    Ni L; Tonthat NK; Chinnam N; Schumacher MA
    Nucleic Acids Res; 2013 Feb; 41(3):1998-2008. PubMed ID: 23241389
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein-ligand interaction: grafting of the uridine-specific determinants from the CytR regulator of Salmonella typhimurium to Escherichia coli CytR.
    Thomsen LE; Pedersen M; Nørregaard-Madsen M; Valentin-Hansen P; Kallipolitis BH
    J Mol Biol; 1999 Apr; 288(1):165-75. PubMed ID: 10329134
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural analysis of the purine repressor, an Escherichia coli DNA-binding protein.
    Schumacher MA; Macdonald JR; Björkman J; Mowbray SL; Brennan RG
    J Biol Chem; 1993 Jun; 268(17):12282-8. PubMed ID: 8509365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Three-dimensional structure of the DNA-binding domain of the fructose repressor from Escherichia coli by 1H and 15N NMR.
    Penin F; Geourjon C; Montserret R; Böckmann A; Lesage A; Yang YS; Bonod-Bidaud C; Cortay JC; Nègre D; Cozzone AJ; Deléage G
    J Mol Biol; 1997 Jul; 270(3):496-510. PubMed ID: 9237914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple co-evolutionary networks are supported by the common tertiary scaffold of the LacI/GalR proteins.
    Parente DJ; Swint-Kruse L
    PLoS One; 2013; 8(12):e84398. PubMed ID: 24391951
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combinations of the alpha-helix-turn-alpha-helix motif of TetR with respective residues from LacI or 434Cro: DNA recognition, inducer binding, and urea-dependent denaturation.
    Backes H; Berens C; Helbl V; Walter S; Schmid FX; Hillen W
    Biochemistry; 1997 May; 36(18):5311-22. PubMed ID: 9154913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Perturbation from a distance: mutations that alter LacI function through long-range effects.
    Swint-Kruse L; Zhan H; Fairbanks BM; Maheshwari A; Matthews KS
    Biochemistry; 2003 Dec; 42(47):14004-16. PubMed ID: 14636069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.