BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 18538359)

  • 1. Proteasomal degradation of IRS-2, but not IRS-1 by calcineurin inhibition: attenuation of insulin-like growth factor-I-induced GSK-3beta and ERK pathways in adrenal chromaffin cells.
    Satoh S; Yanagita T; Maruta T; Nemoto T; Yoshikawa N; Kobayashi H; Tono T; Wada A
    Neuropharmacology; 2008 Jul; 55(1):71-9. PubMed ID: 18538359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhancement of insulin-induced PI3K/Akt/GSK-3beta and ERK signaling by neuronal nicotinic receptor/PKC-alpha/ERK pathway: up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells.
    Sugano T; Yanagita T; Yokoo H; Satoh S; Kobayashi H; Wada A
    J Neurochem; 2006 Jul; 98(1):20-33. PubMed ID: 16805793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive activity of glycogen synthase kinase-3beta: positive regulation of steady-state levels of insulin receptor substrates-1 and -2 in adrenal chromaffin cells.
    Nemoto T; Yokoo H; Satoh S; Yanagita T; Sugano T; Yoshikawa N; Maruta T; Kobayashi H; Wada A
    Brain Res; 2006 Sep; 1110(1):1-12. PubMed ID: 16870161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Homologous posttranscriptional regulation of insulin-like growth factor-I receptor level via glycogen synthase kinase-3beta and mammalian target of rapamycin in adrenal chromaffin cells: effect on tau phosphorylation.
    Nemoto T; Satoh S; Maruta T; Kanai T; Yoshikawa N; Miyazaki S; Yanagita T; Wada A
    Neuropharmacology; 2010 Jun; 58(7):1097-108. PubMed ID: 20144629
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional up-regulation of cell surface Na V 1.7 sodium channels by insulin-like growth factor-1 via inhibition of glycogen synthase kinase-3β in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion.
    Yanagita T; Satoh S; Uezono Y; Matsuo K; Nemoto T; Maruta T; Yoshikawa N; Iwakiri T; Minami K; Murakami M
    Neuropharmacology; 2011 Dec; 61(8):1265-74. PubMed ID: 21816165
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: the role of GSK-3beta in the maintenance of steady-state levels of insulin receptor signaling molecules and Na(v)1.7 sodium channel in adrenal chromaffin cells.
    Nemoto T; Yanagita T; Kanai T; Wada A
    J Pharmacol Sci; 2009 Feb; 109(2):157-61. PubMed ID: 19179806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells.
    Yoshikawa N; Nemoto T; Satoh S; Maruta T; Yanagita T; Chosa E; Wada A
    Neurochem Int; 2010 Jan; 56(1):42-50. PubMed ID: 19737590
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glycogen synthase kinase-3beta: homologous regulation of cell surface insulin receptor level via controlling insulin receptor mRNA stability in adrenal chromaffin cells.
    Yokoo H; Nemoto T; Yanagita T; Satoh S; Yoshikawa N; Maruta T; Wada A
    J Neurochem; 2007 Dec; 103(5):1883-96. PubMed ID: 17883398
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function.
    Li SY; Fang CX; Aberle NS; Ren BH; Ceylan-Isik AF; Ren J
    J Endocrinol; 2005 Sep; 186(3):491-503. PubMed ID: 16135669
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2.
    Ibrahim YH; Byron SA; Cui X; Lee AV; Yee D
    Mol Cancer Res; 2008 Sep; 6(9):1491-8. PubMed ID: 18819936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Up-regulation of cell surface sodium channels by cyclosporin A, FK506, and rapamycin in adrenal chromaffin cells.
    Shiraishi S; Yanagita T; Kobayashi H; Uezono Y; Yokoo H; Minami SI; Takasaki M; Wada A
    J Pharmacol Exp Ther; 2001 May; 297(2):657-65. PubMed ID: 11303055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of Akt mRNA and protein levels by glycogen synthase kinase-3beta in adrenal chromaffin cells: effects of LiCl and SB216763.
    Nemoto T; Kanai T; Yanagita T; Satoh S; Maruta T; Yoshikawa N; Kobayashi H; Wada A
    Eur J Pharmacol; 2008 May; 586(1-3):82-9. PubMed ID: 18395711
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.
    Rui L; Fisher TL; Thomas J; White MF
    J Biol Chem; 2001 Oct; 276(43):40362-7. PubMed ID: 11546773
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Down-regulation of cell surface insulin receptor and insulin receptor substrate-1 phosphorylation by inhibitor of 90-kDa heat-shock protein family: endoplasmic reticulum retention of monomeric insulin receptor precursor with calnexin in adrenal chromaffin cells.
    Saitoh T; Yanagita T; Shiraishi S; Yokoo H; Kobayashi H; Minami S; Onitsuka T; Wada A
    Mol Pharmacol; 2002 Oct; 62(4):847-55. PubMed ID: 12237331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibition.
    Lee AV; Gooch JL; Oesterreich S; Guler RL; Yee D
    Mol Cell Biol; 2000 Mar; 20(5):1489-96. PubMed ID: 10669726
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling.
    Sharfi H; Eldar-Finkelman H
    Am J Physiol Endocrinol Metab; 2008 Feb; 294(2):E307-15. PubMed ID: 18029441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
    Tanioka T; Tamura Y; Fukaya M; Shinozaki S; Mao J; Kim M; Shimizu N; Kitamura T; Kaneki M
    J Biol Chem; 2011 Aug; 286(33):29388-29396. PubMed ID: 21700708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.
    Briaud I; Dickson LM; Lingohr MK; McCuaig JF; Lawrence JC; Rhodes CJ
    J Biol Chem; 2005 Jan; 280(3):2282-93. PubMed ID: 15537654
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling.
    Sun H; Tu X; Liu M; Baserga R
    J Cell Physiol; 2007 Sep; 212(3):780-6. PubMed ID: 17443674
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.