185 related articles for article (PubMed ID: 18540626)
1. Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals.
Satsu H; Hiura Y; Mochizuki K; Hamada M; Shimizu M
J Agric Food Chem; 2008 Jul; 56(13):5366-73. PubMed ID: 18540626
[TBL] [Abstract][Full Text] [Related]
2. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
[TBL] [Abstract][Full Text] [Related]
3. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
4. Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.
Feng D; Tang T; Fan R; Luo J; Cui H; Wang Y; Gan P
BMC Complement Altern Med; 2018 Dec; 18(1):345. PubMed ID: 30594244
[TBL] [Abstract][Full Text] [Related]
5. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
Li Y; Wang Q; Yao X; Li Y
Eur J Pharmacol; 2010 Aug; 640(1-3):46-54. PubMed ID: 20580705
[TBL] [Abstract][Full Text] [Related]
6. Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells.
Liu CL; Lim YP; Hu ML
Mar Drugs; 2012 Jan; 10(1):242-257. PubMed ID: 22363234
[TBL] [Abstract][Full Text] [Related]
7. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.
Masuyama H; Suwaki N; Tateishi Y; Nakatsukasa H; Segawa T; Hiramatsu Y
Mol Endocrinol; 2005 May; 19(5):1170-80. PubMed ID: 15650019
[TBL] [Abstract][Full Text] [Related]
8. Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides.
Lau AJ; Yang G; Rajaraman G; Baucom CC; Chang TK
J Pharmacol Exp Ther; 2010 Dec; 335(3):771-80. PubMed ID: 20739453
[TBL] [Abstract][Full Text] [Related]
9. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
[TBL] [Abstract][Full Text] [Related]
10. The effects of splicing variant of PXR PAR-2 on CYP3A4 and MDR1 mRNA expressions.
Liu Y; Ji W; Yin Y; Fan L; Zhang J; Yun H; Wang N; Li Q; Wei Z; Ouyang D; Zhou HH
Clin Chim Acta; 2009 May; 403(1-2):142-4. PubMed ID: 19232333
[TBL] [Abstract][Full Text] [Related]
11. Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.
Pondugula SR; Flannery PC; Abbott KL; Coleman ES; Mani S; Samuel T; Xie W
Toxicol Lett; 2015 Feb; 232(3):580-9. PubMed ID: 25542144
[TBL] [Abstract][Full Text] [Related]
12. Transport of 5,5-diphenylbarbituric acid and its precursors and their effect on P-gp, MRP2 and CYP3A4 in Caco-2 and LS180 cells.
Fan J; Maeng HJ; Du Y; Kwan D; Pang KS
Eur J Pharm Sci; 2011 Jan; 42(1-2):19-29. PubMed ID: 20955791
[TBL] [Abstract][Full Text] [Related]
13. Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.
Wang YM; Lin W; Chai SC; Wu J; Ong SS; Schuetz EG; Chen T
Toxicol Appl Pharmacol; 2013 Oct; 272(1):96-107. PubMed ID: 23707768
[TBL] [Abstract][Full Text] [Related]
14. Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells.
Weiss J; Theile D; Spalwisz A; Burhenne J; Riedel KD; Haefeli WE
Biochem Pharmacol; 2013 Jan; 85(2):265-73. PubMed ID: 23219525
[TBL] [Abstract][Full Text] [Related]
15. Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway.
Awortwe C; Manda VK; Avonto C; Khan SI; Khan IA; Walker LA; Bouic PJ; Rosenkranz B
Xenobiotica; 2015 Mar; 45(3):218-29. PubMed ID: 25377539
[TBL] [Abstract][Full Text] [Related]
16. Effects of budesonide on P-glycoprotein expression in intestinal cell lines.
Maier A; Zimmermann C; Beglinger C; Drewe J; Gutmann H
Br J Pharmacol; 2007 Feb; 150(3):361-8. PubMed ID: 17179942
[TBL] [Abstract][Full Text] [Related]
17. Shear stress activation of nuclear receptor PXR in endothelial detoxification.
Wang X; Fang X; Zhou J; Chen Z; Zhao B; Xiao L; Liu A; Li YS; Shyy JY; Guan Y; Chien S; Wang N
Proc Natl Acad Sci U S A; 2013 Aug; 110(32):13174-9. PubMed ID: 23878263
[TBL] [Abstract][Full Text] [Related]
18. Differential effects of the enantiomers of tamsulosin and tolterodine on P-glycoprotein and cytochrome P450 3A4.
Doricakova A; Theile D; Weiss J; Vrzal R
Naunyn Schmiedebergs Arch Pharmacol; 2017 Jan; 390(1):49-59. PubMed ID: 27678410
[TBL] [Abstract][Full Text] [Related]
19. Essential oils of culinary herbs and spices activate PXR and induce CYP3A4 in human intestinal and hepatic in vitro models.
Bartonkova I; Dvorak Z
Toxicol Lett; 2018 Oct; 296():1-9. PubMed ID: 30071242
[TBL] [Abstract][Full Text] [Related]
20. Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation.
Zhou T; You WT; Ma ZC; Liang QD; Tan HL; Xiao CR; Tang XL; Zhang BL; Wang YG; Gao Y
Acta Pharmacol Sin; 2016 Feb; 37(2):177-86. PubMed ID: 26775663
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
