BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

328 related articles for article (PubMed ID: 18544565)

  • 1. Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells.
    Ko JC; Ciou SC; Cheng CM; Wang LH; Hong JH; Jheng MY; Ling ST; Lin YW
    Carcinogenesis; 2008 Jul; 29(7):1448-58. PubMed ID: 18544565
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of Rad51 down-regulation and extracellular signal-regulated kinases 1 and 2 inactivation in emodin and mitomycin C-induced synergistic cytotoxicity in human non-small-cell lung cancer cells.
    Su YJ; Tsai MS; Kuo YH; Chiu YF; Cheng CM; Lin ST; Lin YW
    Mol Pharmacol; 2010 Apr; 77(4):633-43. PubMed ID: 20042515
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo[a]pyrene in human lung cancer.
    Ko JC; Hong JH; Wang LH; Lin YW
    Exp Cell Res; 2008 May; 314(8):1881-91. PubMed ID: 18377894
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells.
    Ko JC; Tsai MS; Weng SH; Kuo YH; Chiu YF; Lin YW
    Toxicol Appl Pharmacol; 2011 Sep; 255(3):327-38. PubMed ID: 21810436
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation.
    Chen RS; Jhan JY; Su YJ; Lee WT; Cheng CM; Ciou SC; Lin ST; Chuang SM; Ko JC; Lin YW
    Exp Cell Res; 2009 Sep; 315(15):2658-72. PubMed ID: 19505457
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of celecoxib in Rad51 expression and cell survival affected by gefitinib in human non-small cell lung cancer cells.
    Ko JC; Wang LH; Jhan JY; Ciou SC; Hong JH; Lin ST; Lin YW
    Lung Cancer; 2009 Sep; 65(3):290-8. PubMed ID: 19157634
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of MKK1/2-ERK1/2 and phosphoinositide 3-kinase-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells.
    Ko JC; Ciou SC; Jhan JY; Cheng CM; Su YJ; Chuang SM; Lin ST; Chang CC; Lin YW
    Mol Cancer Res; 2009 Aug; 7(8):1378-89. PubMed ID: 19671683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of repair protein Rad51 in regulating the response to gefitinib in human non-small cell lung cancer cells.
    Ko JC; Hong JH; Wang LH; Cheng CM; Ciou SC; Lin ST; Jheng MY; Lin YW
    Mol Cancer Ther; 2008 Nov; 7(11):3632-41. PubMed ID: 19001445
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of Rad51, ERCC1, and thymidine phosphorylase by emodin result in synergistic cytotoxic effect in combination with capecitabine.
    Ko JC; Tsai MS; Kuo YH; Chiu YF; Weng SH; Su YC; Lin YW
    Biochem Pharmacol; 2011 Mar; 81(5):680-90. PubMed ID: 21168393
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Minocycline enhances mitomycin C-induced cytotoxicity through down-regulating ERK1/2-mediated Rad51 expression in human non-small cell lung cancer cells.
    Ko JC; Wang TJ; Chang PY; Syu JJ; Chen JC; Chen CY; Jian YT; Jian YJ; Zheng HY; Chen WC; Lin YW
    Biochem Pharmacol; 2015 Oct; 97(3):331-40. PubMed ID: 26212550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2.
    Ko JC; Su YJ; Lin ST; Jhan JY; Ciou SC; Cheng CM; Chiu YF; Kuo YH; Tsai MS; Lin YW
    Lung Cancer; 2010 Aug; 69(2):155-64. PubMed ID: 19962780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells.
    Tung CL; Jian YJ; Syu JJ; Wang TJ; Chang PY; Chen CY; Jian YT; Lin YW
    Exp Cell Res; 2015 May; 334(1):126-35. PubMed ID: 25662161
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non--Small-Cell Lung Cancer Cells.
    Liu JT; Li WC; Gao S; Wang F; Li XQ; Yu HQ; Fan LL; Wei W; Wang H; Sun GP
    Clin Lung Cancer; 2015 Sep; 16(5):e55-66. PubMed ID: 25979647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppression of ERCC1 and Rad51 expression through ERK1/2 inactivation is essential in emodin-mediated cytotoxicity in human non-small cell lung cancer cells.
    Ko JC; Su YJ; Lin ST; Jhan JY; Ciou SC; Cheng CM; Lin YW
    Biochem Pharmacol; 2010 Feb; 79(4):655-64. PubMed ID: 19799875
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down-regulation of Rad51 expression overcomes drug resistance to gemcitabine in human non-small-cell lung cancer cells.
    Tsai MS; Kuo YH; Chiu YF; Su YC; Lin YW
    J Pharmacol Exp Ther; 2010 Dec; 335(3):830-40. PubMed ID: 20855443
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Up-regulation of extracellular signal-regulated kinase 1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small-cell lung cancer cells.
    Ko JC; Tsai MS; Chiu YF; Weng SH; Kuo YH; Lin YW
    J Pharmacol Exp Ther; 2011 Jul; 338(1):184-94. PubMed ID: 21444628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor.
    Huang S; Armstrong EA; Benavente S; Chinnaiyan P; Harari PM
    Cancer Res; 2004 Aug; 64(15):5355-62. PubMed ID: 15289342
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancement of mitomycin C-induced cytotoxicity by curcumin results from down-regulation of MKK1/2-ERK1/2-mediated thymidine phosphorylase expression.
    Weng SH; Tsai MS; Chiu YF; Kuo YH; Chen HJ; Lin YW
    Basic Clin Pharmacol Toxicol; 2012 Mar; 110(3):298-306. PubMed ID: 21973306
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects.
    Stabile LP; Lyker JS; Gubish CT; Zhang W; Grandis JR; Siegfried JM
    Cancer Res; 2005 Feb; 65(4):1459-70. PubMed ID: 15735034
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Astaxanthin down-regulates Rad51 expression via inactivation of AKT kinase to enhance mitomycin C-induced cytotoxicity in human non-small cell lung cancer cells.
    Ko JC; Chen JC; Wang TJ; Zheng HY; Chen WC; Chang PY; Lin YW
    Biochem Pharmacol; 2016 Apr; 105():91-100. PubMed ID: 26921637
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.