782 related articles for article (PubMed ID: 18549781)
1. ApoE promotes the proteolytic degradation of Abeta.
Jiang Q; Lee CY; Mandrekar S; Wilkinson B; Cramer P; Zelcer N; Mann K; Lamb B; Willson TM; Collins JL; Richardson JC; Smith JD; Comery TA; Riddell D; Holtzman DM; Tontonoz P; Landreth GE
Neuron; 2008 Jun; 58(5):681-93. PubMed ID: 18549781
[TBL] [Abstract][Full Text] [Related]
2. The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E.
Namjoshi DR; Martin G; Donkin J; Wilkinson A; Stukas S; Fan J; Carr M; Tabarestani S; Wuerth K; Hancock RE; Wellington CL
PLoS One; 2013; 8(1):e53529. PubMed ID: 23349715
[TBL] [Abstract][Full Text] [Related]
3. Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice.
Fitz NF; Cronican A; Pham T; Fogg A; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2010 May; 30(20):6862-72. PubMed ID: 20484628
[TBL] [Abstract][Full Text] [Related]
4. Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice.
Skerrett R; Pellegrino MP; Casali BT; Taraboanta L; Landreth GE
J Biol Chem; 2015 Aug; 290(35):21591-602. PubMed ID: 26163517
[TBL] [Abstract][Full Text] [Related]
5. ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.
Donkin JJ; Stukas S; Hirsch-Reinshagen V; Namjoshi D; Wilkinson A; May S; Chan J; Fan J; Collins J; Wellington CL
J Biol Chem; 2010 Oct; 285(44):34144-54. PubMed ID: 20739291
[TBL] [Abstract][Full Text] [Related]
6. The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease.
Riddell DR; Zhou H; Comery TA; Kouranova E; Lo CF; Warwick HK; Ring RH; Kirksey Y; Aschmies S; Xu J; Kubek K; Hirst WD; Gonzales C; Chen Y; Murphy E; Leonard S; Vasylyev D; Oganesian A; Martone RL; Pangalos MN; Reinhart PH; Jacobsen JS
Mol Cell Neurosci; 2007 Apr; 34(4):621-8. PubMed ID: 17336088
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and identification of new flavonoids targeting liver X receptor β involved pathway as potential facilitators of Aβ clearance with reduced lipid accumulation.
Hu Y; Yang Y; Yu Y; Wen G; Shang N; Zhuang W; Lu D; Zhou B; Liang B; Yue X; Li F; Du J; Bu X
J Med Chem; 2013 Aug; 56(15):6033-53. PubMed ID: 23844653
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease.
Mandrekar-Colucci S; Karlo JC; Landreth GE
J Neurosci; 2012 Jul; 32(30):10117-28. PubMed ID: 22836247
[TBL] [Abstract][Full Text] [Related]
9. ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Cramer PE; Cirrito JR; Wesson DW; Lee CY; Karlo JC; Zinn AE; Casali BT; Restivo JL; Goebel WD; James MJ; Brunden KR; Wilson DA; Landreth GE
Science; 2012 Mar; 335(6075):1503-6. PubMed ID: 22323736
[TBL] [Abstract][Full Text] [Related]
10. Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis.
Terwel D; Steffensen KR; Verghese PB; Kummer MP; Gustafsson JÅ; Holtzman DM; Heneka MT
J Neurosci; 2011 May; 31(19):7049-59. PubMed ID: 21562267
[TBL] [Abstract][Full Text] [Related]
11. Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo.
Tai LM; Koster KP; Luo J; Lee SH; Wang YT; Collins NC; Ben Aissa M; Thatcher GRJ; LaDu MJ
J Biol Chem; 2014 Oct; 289(44):30538-30555. PubMed ID: 25217640
[TBL] [Abstract][Full Text] [Related]
12. Role of Liver X Receptor in AD Pathophysiology.
Sandoval-Hernández AG; Buitrago L; Moreno H; Cardona-Gómez GP; Arboleda G
PLoS One; 2015; 10(12):e0145467. PubMed ID: 26720273
[TBL] [Abstract][Full Text] [Related]
13. ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice.
Corona AW; Kodoma N; Casali BT; Landreth GE
J Neuroimmune Pharmacol; 2016 Mar; 11(1):61-72. PubMed ID: 26175148
[TBL] [Abstract][Full Text] [Related]
14. Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
Fryer JD; Simmons K; Parsadanian M; Bales KR; Paul SM; Sullivan PM; Holtzman DM
J Neurosci; 2005 Mar; 25(11):2803-10. PubMed ID: 15772340
[TBL] [Abstract][Full Text] [Related]
15. Improvement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonist.
Fitz NF; Castranio EL; Carter AY; Kodali R; Lefterov I; Koldamova R
J Alzheimers Dis; 2014; 41(2):535-49. PubMed ID: 24643138
[TBL] [Abstract][Full Text] [Related]
16. Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.
Wahrle SE; Jiang H; Parsadanian M; Hartman RE; Bales KR; Paul SM; Holtzman DM
J Biol Chem; 2005 Dec; 280(52):43236-42. PubMed ID: 16207708
[TBL] [Abstract][Full Text] [Related]
17. Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse model of Alzheimer's disease.
Kawahara K; Suenobu M; Ohtsuka H; Kuniyasu A; Sugimoto Y; Nakagomi M; Fukasawa H; Shudo K; Nakayama H
J Alzheimers Dis; 2014; 42(2):587-605. PubMed ID: 24916544
[TBL] [Abstract][Full Text] [Related]
18. Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.
Fan J; Donkin J; Wellington C
Biofactors; 2009; 35(3):239-48. PubMed ID: 19472365
[TBL] [Abstract][Full Text] [Related]
19. High-density lipoprotein mimetic peptide 4F mitigates amyloid-β-induced inhibition of apolipoprotein E secretion and lipidation in primary astrocytes and microglia.
Chernick D; Ortiz-Valle S; Jeong A; Swaminathan SK; Kandimalla KK; Rebeck GW; Li L
J Neurochem; 2018 Dec; 147(5):647-662. PubMed ID: 30028014
[TBL] [Abstract][Full Text] [Related]
20. Blocking the apolipoprotein E/amyloid-β interaction reduces fibrillar vascular amyloid deposition and cerebral microhemorrhages in TgSwDI mice.
Yang J; Ji Y; Mehta P; Bates KA; Sun Y; Wisniewski T
J Alzheimers Dis; 2011; 24(2):269-85. PubMed ID: 21239853
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
