BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 18549880)

  • 1. Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas.
    Park SW; Davison JM; Rhee J; Hruban RH; Maitra A; Leach SD
    Gastroenterology; 2008 Jun; 134(7):2080-90. PubMed ID: 18549880
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of Kras-mediated pancreatic tumorigenesis in zebrafish.
    Davison JM; Woo Park S; Rhee JM; Leach SD
    Methods Enzymol; 2008; 438():391-417. PubMed ID: 18413263
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer.
    Schiavone M; Rampazzo E; Casari A; Battilana G; Persano L; Moro E; Liu S; Leach SD; Tiso N; Argenton F
    Dis Model Mech; 2014 Jul; 7(7):883-94. PubMed ID: 24878567
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Screening pancreatic oncogenes in zebrafish using the Gal4/UAS system.
    Liu S; Leach SD
    Methods Cell Biol; 2011; 105():367-81. PubMed ID: 21951538
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic KRAS promotes malignant brain tumors in zebrafish.
    Ju B; Chen W; Orr BA; Spitsbergen JM; Jia S; Eden CJ; Henson HE; Taylor MR
    Mol Cancer; 2015 Feb; 14(1):18. PubMed ID: 25644510
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey.
    Park JT; Johnson N; Liu S; Levesque M; Wang YJ; Ho H; Huso D; Maitra A; Parsons MJ; Prescott JD; Leach SD
    Oncogene; 2015 May; 34(21):2801-6. PubMed ID: 25065594
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles for KRAS in pancreatic tumor development and progression.
    di Magliano MP; Logsdon CD
    Gastroenterology; 2013 Jun; 144(6):1220-9. PubMed ID: 23622131
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-κB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells.
    Bera A; Zhao S; Cao L; Chiao PJ; Freeman JW
    PLoS One; 2013; 8(12):e82282. PubMed ID: 24340014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice.
    Kopp JL; Dubois CL; Schaeffer DF; Samani A; Taghizadeh F; Cowan RW; Rhim AD; Stiles BL; Valasek M; Sander M
    Gastroenterology; 2018 Apr; 154(5):1509-1523.e5. PubMed ID: 29273451
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
    Ray KC; Moss ME; Franklin JL; Weaver CJ; Higginbotham J; Song Y; Revetta FL; Blaine SA; Bridges LR; Guess KE; Coffey RJ; Crawford HC; Washington MK; Means AL
    Oncogene; 2014 Feb; 33(7):823-31. PubMed ID: 23376846
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
    Chen NM; Singh G; Koenig A; Liou GY; Storz P; Zhang JS; Regul L; Nagarajan S; Kühnemuth B; Johnsen SA; Hebrok M; Siveke J; Billadeau DD; Ellenrieder V; Hessmann E
    Gastroenterology; 2015 May; 148(5):1024-1034.e9. PubMed ID: 25623042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice.
    Habbe N; Shi G; Meguid RA; Fendrich V; Esni F; Chen H; Feldmann G; Stoffers DA; Konieczny SF; Leach SD; Maitra A
    Proc Natl Acad Sci U S A; 2008 Dec; 105(48):18913-8. PubMed ID: 19028870
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ribonucleoprotein HNRNPA2B1 interacts with and regulates oncogenic KRAS in pancreatic ductal adenocarcinoma cells.
    Barceló C; Etchin J; Mansour MR; Sanda T; Ginesta MM; Sanchez-Arévalo Lobo VJ; Real FX; Capellà G; Estanyol JM; Jaumot M; Look AT; Agell N
    Gastroenterology; 2014 Oct; 147(4):882-892.e8. PubMed ID: 24998203
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
    Mameishvili E; Serafimidis I; Iwaszkiewicz S; Lesche M; Reinhardt S; Bölicke N; Büttner M; Stellas D; Papadimitropoulou A; Szabolcs M; Anastassiadis K; Dahl A; Theis F; Efstratiadis A; Gavalas A
    Proc Natl Acad Sci U S A; 2019 Oct; 116(41):20679-20688. PubMed ID: 31548432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct enhancers of ptf1a mediate specification and expansion of ventral pancreas in zebrafish.
    Pashos E; Park JT; Leach S; Fisher S
    Dev Biol; 2013 Sep; 381(2):471-81. PubMed ID: 23876428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice.
    Ogawa S; Fukuda A; Matsumoto Y; Hanyu Y; Sono M; Fukunaga Y; Masuda T; Araki O; Nagao M; Yoshikawa T; Goto N; Hiramatsu Y; Tsuda M; Maruno T; Nakanishi Y; Hussein MS; Tsuruyama T; Takaori K; Uemoto S; Seno H
    Gastroenterology; 2020 Aug; 159(2):682-696.e13. PubMed ID: 32360551
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
    Ji Z; Mei FC; Xie J; Cheng X
    J Biol Chem; 2007 May; 282(19):14048-55. PubMed ID: 17353198
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.
    Barceló C; Paco N; Morell M; Alvarez-Moya B; Bota-Rabassedas N; Jaumot M; Vilardell F; Capella G; Agell N
    Cancer Res; 2014 Feb; 74(4):1190-9. PubMed ID: 24371225
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia.
    De La O JP; Emerson LL; Goodman JL; Froebe SC; Illum BE; Curtis AB; Murtaugh LC
    Proc Natl Acad Sci U S A; 2008 Dec; 105(48):18907-12. PubMed ID: 19028876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.