BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 18551038)

  • 1. Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.
    Celtikci B; Leclerc D; Lawrance AK; Deng L; Friedman HC; Krupenko NI; Krupenko SA; Melnyk S; James SJ; Peterson AC; Rozen R
    Pharmacogenet Genomics; 2008 Jul; 18(7):577-89. PubMed ID: 18551038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase.
    Celtikci B; Lawrance AK; Wu Q; Rozen R
    Anticancer Drugs; 2009 Oct; 20(9):787-93. PubMed ID: 19593106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
    Wessels JA; de Vries-Bouwstra JK; Heijmans BT; Slagboom PE; Goekoop-Ruiterman YP; Allaart CF; Kerstens PJ; van Zeben D; Breedveld FC; Dijkmans BA; Huizinga TW; Guchelaar HJ
    Arthritis Rheum; 2006 Apr; 54(4):1087-95. PubMed ID: 16572443
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
    Schmeling H; Biber D; Heins S; Horneff G
    J Rheumatol; 2005 Sep; 32(9):1832-6. PubMed ID: 16142884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.
    Fodil-Cornu N; Kozij N; Wu Q; Rozen R; Vidal SM
    Genes Immun; 2009 Oct; 10(7):662-6. PubMed ID: 19609317
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.
    Toffoli G; Russo A; Innocenti F; Corona G; Tumolo S; Sartor F; Mini E; Boiocchi M
    Int J Cancer; 2003 Jan; 103(3):294-9. PubMed ID: 12471611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS.
    Mikael LG; Rozen R
    Cardiovasc Res; 2008 Oct; 80(1):151-8. PubMed ID: 18540024
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia.
    Nagele P; Zeugswetter B; Wiener C; Burger H; Hüpfl M; Mittlböck M; Födinger M
    Anesthesiology; 2008 Jul; 109(1):36-43. PubMed ID: 18580170
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia.
    Kishi S; Griener J; Cheng C; Das S; Cook EH; Pei D; Hudson M; Rubnitz J; Sandlund JT; Pui CH; Relling MV
    J Clin Oncol; 2003 Aug; 21(16):3084-91. PubMed ID: 12915598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toxic encephalopathy and delayed MTX clearance after high-dose methotrexate therapy in a child homozygous for the MTHFR C677T polymorphism.
    Müller J; Kralovánszky J; Adleff V; Pap E; Németh K; Komlósi V; Kovács G
    Anticancer Res; 2008; 28(5B):3051-4. PubMed ID: 19031955
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct association of SLC19A1 polymorphism -43T>C with red cell folate levels and of MTHFR polymorphism 677C>T with plasma folate levels.
    Chatzikyriakidou A; Vakalis KV; Kolaitis N; Kolios G; Naka KK; Michalis LK; Georgiou I
    Clin Biochem; 2008 Feb; 41(3):174-6. PubMed ID: 18053808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.
    Aplenc R; Thompson J; Han P; La M; Zhao H; Lange B; Rebbeck T
    Cancer Res; 2005 Mar; 65(6):2482-7. PubMed ID: 15781665
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
    Lawrance AK; Deng L; Rozen R
    Gut; 2009 Jun; 58(6):805-11. PubMed ID: 19174418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.
    D'Angelo V; Ramaglia M; Iannotta A; Crisci S; Indolfi P; Francese M; Affinita MC; Pecoraro G; Napolitano A; Fusco C; Oreste M; Indolfi C; Casale F
    Cancer Chemother Pharmacol; 2011 Nov; 68(5):1339-46. PubMed ID: 21590445
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts.
    Chiang EP; Wang YC; Tang FY
    Leukemia; 2007 Apr; 21(4):651-8. PubMed ID: 17301815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.
    De Mattia E; Toffoli G
    Eur J Cancer; 2009 May; 45(8):1333-51. PubMed ID: 19144510
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.
    Weisman MH; Furst DE; Park GS; Kremer JM; Smith KM; Wallace DJ; Caldwell JR; Dervieux T
    Arthritis Rheum; 2006 Feb; 54(2):607-12. PubMed ID: 16447238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis.
    Fujimaki C; Hayashi H; Tsuboi S; Matsuyama T; Kosuge K; Yamada H; Inoue K; Itoh K
    Biomarkers; 2009 Feb; 14(1):49-54. PubMed ID: 19283524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
    Sohn KJ; Croxford R; Yates Z; Lucock M; Kim YI
    J Natl Cancer Inst; 2004 Jan; 96(2):134-44. PubMed ID: 14734703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
    Lin PT; Huang MC; Lee BJ; Cheng CH; Tsai TP; Huang YC
    Asia Pac J Clin Nutr; 2008; 17(2):330-8. PubMed ID: 18586656
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.