These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria. Sarkissian CN; Gámez A; Wang L; Charbonneau M; Fitzpatrick P; Lemontt JF; Zhao B; Vellard M; Bell SM; Henschell C; Lambert A; Tsuruda L; Stevens RC; Scriver CR Proc Natl Acad Sci U S A; 2008 Dec; 105(52):20894-9. PubMed ID: 19095795 [TBL] [Abstract][Full Text] [Related]
5. Converting an injectable protein therapeutic into an oral form: phenylalanine ammonia lyase for phenylketonuria. Kang TS; Wang L; Sarkissian CN; Gámez A; Scriver CR; Stevens RC Mol Genet Metab; 2010 Jan; 99(1):4-9. PubMed ID: 19793667 [TBL] [Abstract][Full Text] [Related]
6. Crystal structure of phenylalanine ammonia lyase: multiple helix dipoles implicated in catalysis. Calabrese JC; Jordan DB; Boodhoo A; Sariaslani S; Vannelli T Biochemistry; 2004 Sep; 43(36):11403-16. PubMed ID: 15350127 [TBL] [Abstract][Full Text] [Related]
7. Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization. Moffitt MC; Louie GV; Bowman ME; Pence J; Noel JP; Moore BS Biochemistry; 2007 Jan; 46(4):1004-12. PubMed ID: 17240984 [TBL] [Abstract][Full Text] [Related]
8. Biochemical and Structural Analysis of Substrate Specificity of a Phenylalanine Ammonia-Lyase. Jun SY; Sattler SA; Cortez GS; Vermerris W; Sattler SE; Kang C Plant Physiol; 2018 Feb; 176(2):1452-1468. PubMed ID: 29196539 [TBL] [Abstract][Full Text] [Related]
9. Bacterial Anabaena variabilis phenylalanine ammonia lyase: a biocatalyst with broad substrate specificity. Lovelock SL; Turner NJ Bioorg Med Chem; 2014 Oct; 22(20):5555-7. PubMed ID: 25037641 [TBL] [Abstract][Full Text] [Related]
10. The essential tyrosine-containing loop conformation and the role of the C-terminal multi-helix region in eukaryotic phenylalanine ammonia-lyases. Pilbák S; Tomin A; Rétey J; Poppe L FEBS J; 2006 Mar; 273(5):1004-19. PubMed ID: 16478474 [TBL] [Abstract][Full Text] [Related]
11. Evaluation of orally administered PEGylated phenylalanine ammonia lyase in mice for the treatment of Phenylketonuria. Sarkissian CN; Kang TS; Gámez A; Scriver CR; Stevens RC Mol Genet Metab; 2011 Nov; 104(3):249-54. PubMed ID: 21803624 [TBL] [Abstract][Full Text] [Related]
12. Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Wang L; Gamez A; Sarkissian CN; Straub M; Patch MG; Han GW; Striepeke S; Fitzpatrick P; Scriver CR; Stevens RC Mol Genet Metab; 2005; 86(1-2):134-40. PubMed ID: 16006165 [TBL] [Abstract][Full Text] [Related]
13. Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase. Heberling MM; Masman MF; Bartsch S; Wybenga GG; Dijkstra BW; Marrink SJ; Janssen DB ACS Chem Biol; 2015 Apr; 10(4):989-97. PubMed ID: 25494407 [TBL] [Abstract][Full Text] [Related]
14. Analysis of the gene for phenylalanine ammonia-lyase from Rhodosporidium toruloides. Rasmussen OF; Oerum H DNA Seq; 1991; 1(3):207-11. PubMed ID: 1773059 [TBL] [Abstract][Full Text] [Related]
15. Biomedical applications of microbial phenylalanine ammonia lyase: Current status and future prospects. Kawatra A; Dhankhar R; Mohanty A; Gulati P Biochimie; 2020 Oct; 177():142-152. PubMed ID: 32828824 [TBL] [Abstract][Full Text] [Related]
16. Engineering and kinetic stabilization of the therapeutic enzyme Anabeana variabilis phenylalanine ammonia lyase. Jaliani HZ; Farajnia S; Mohammadi SA; Barzegar A; Talebi S Appl Biochem Biotechnol; 2013 Dec; 171(7):1805-18. PubMed ID: 23999738 [TBL] [Abstract][Full Text] [Related]
17. A comprehensive in silico characterization of bacterial signal peptides for the excretory production of Owji H; Hemmati S 3 Biotech; 2018 Dec; 8(12):488. PubMed ID: 30498661 [No Abstract] [Full Text] [Related]
18. One-Pot Enzymatic Synthesis of D-Arylalanines Using Phenylalanine Ammonia Lyase and L-Amino Acid Deaminase. Zhu L; Feng G; Ge F; Song P; Wang T; Liu Y; Tao Y; Zhou Z Appl Biochem Biotechnol; 2019 Jan; 187(1):75-89. PubMed ID: 29882193 [TBL] [Abstract][Full Text] [Related]
19. An active site homology model of phenylalanine ammonia-lyase from Petroselinum crispum. Röther D; Poppe L; Morlock G; Viergutz S; Rétey J Eur J Biochem; 2002 Jun; 269(12):3065-75. PubMed ID: 12071972 [TBL] [Abstract][Full Text] [Related]