BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 18566480)

  • 1. Monoclonal antibody-based screening assay for factor inhibiting hypoxia-inducible factor inhibitors.
    Lee SH; Jeong Hee Moon ; Eun Ah Cho ; Ryu SE; Myung Kyu Lee
    J Biomol Screen; 2008 Jul; 13(6):494-503. PubMed ID: 18566480
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
    Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
    FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
    Wilkins SE; Hyvärinen J; Chicher J; Gorman JJ; Peet DJ; Bilton RL; Koivunen P
    Int J Biochem Cell Biol; 2009 Jul; 41(7):1563-71. PubMed ID: 19401150
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.
    Linke S; Stojkoski C; Kewley RJ; Booker GW; Whitelaw ML; Peet DJ
    J Biol Chem; 2004 Apr; 279(14):14391-7. PubMed ID: 14734545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
    Webb JD; Murányi A; Pugh CW; Ratcliffe PJ; Coleman ML
    Biochem J; 2009 May; 420(2):327-33. PubMed ID: 19245366
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
    Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
    J Biol Chem; 2002 Jul; 277(29):26351-5. PubMed ID: 12042299
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
    Jin P; Kang J; Lee MK; Park JW
    Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
    Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
    Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
    J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
    Chen DY; Fabrizio JA; Wilkins SE; Dave KA; Gorman JJ; Gleadle JM; Fleming SB; Peet DJ; Mercer AA
    J Virol; 2017 Jan; 91(1):. PubMed ID: 27795413
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
    Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
    Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases.
    Kanelakis KC; Palomino HL; Li L; Wu J; Yan W; Rosen MD; Rizzolio MC; Trivedi M; Morton MF; Yang Y; Venkatesan H; Rabinowitz MH; Shankley NP; Barrett TD
    J Biomol Screen; 2009 Jul; 14(6):627-35. PubMed ID: 19498081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.
    Lancaster DE; McNeill LA; McDonough MA; Aplin RT; Hewitson KS; Pugh CW; Ratcliffe PJ; Schofield CJ
    Biochem J; 2004 Nov; 383(Pt. 3):429-37. PubMed ID: 15239670
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Siah-1 facilitates ubiquitination and degradation of factor inhibiting HIF-1alpha (FIH).
    Fukuba H; Yamashita H; Nagano Y; Jin HG; Hiji M; Ohtsuki T; Takahashi T; Kohriyama T; Matsumoto M
    Biochem Biophys Res Commun; 2007 Feb; 353(2):324-9. PubMed ID: 17188242
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
    Cockman ME; Webb JD; Kramer HB; Kessler BM; Ratcliffe PJ
    Mol Cell Proteomics; 2009 Mar; 8(3):535-46. PubMed ID: 18936059
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Featured Article: Hypoxia-inducible factor-1α dependent nuclear entry of factor inhibiting HIF-1.
    Liang K; Ding XQ; Lin C; Kang YJ
    Exp Biol Med (Maywood); 2015 Nov; 240(11):1446-51. PubMed ID: 25687434
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia-inducible factor 1 (HIF-1) pathway.
    Semenza GL
    Sci STKE; 2007 Oct; 2007(407):cm8. PubMed ID: 17925579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression and role of factor inhibiting hypoxia-inducible factor-1 in pulmonary arteries of rat with hypoxia-induced hypertension.
    Fu D; Dai A; Hu R; Chen Y; Zhu L
    Acta Biochim Biophys Sin (Shanghai); 2008 Oct; 40(10):883-92. PubMed ID: 18850054
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
    Nguyen LK; Cavadas MA; Scholz CC; Fitzpatrick SF; Bruning U; Cummins EP; Tambuwala MM; Manresa MC; Kholodenko BN; Taylor CT; Cheong A
    J Cell Sci; 2013 Mar; 126(Pt 6):1454-63. PubMed ID: 23390316
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1.
    Shin DH; Chun YS; Lee DS; Huang LE; Park JW
    Blood; 2008 Mar; 111(6):3131-6. PubMed ID: 18174379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.