59 related articles for article (PubMed ID: 18566513)
1. Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Pallarès I; Fernández D; Comellas-Bigler M; Fernández-Recio J; Ventura S; Avilés FX; Bode W; Vendrell J
Acta Crystallogr D Biol Crystallogr; 2008 Jul; D64(Pt 7):784-91. PubMed ID: 18566513
[TBL] [Abstract][Full Text] [Related]
2. Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate.
Smith GK; Banks S; Blumenkopf TA; Cory M; Humphreys J; Laethem RM; Miller J; Moxham CP; Mullin R; Ray PH; Walton LM; Wolfe LA
J Biol Chem; 1997 Jun; 272(25):15804-16. PubMed ID: 9188478
[TBL] [Abstract][Full Text] [Related]
3. The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode.
Arolas JL; Popowicz GM; Lorenzo J; Sommerhoff CP; Huber R; Aviles FX; Holak TA
J Mol Biol; 2005 Jul; 350(3):489-98. PubMed ID: 15961103
[TBL] [Abstract][Full Text] [Related]
4. Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.
Laethem RM; Blumenkopf TA; Cory M; Elwell L; Moxham CP; Ray PH; Walton LM; Smith GK
Arch Biochem Biophys; 1996 Aug; 332(1):8-18. PubMed ID: 8806703
[TBL] [Abstract][Full Text] [Related]
5. The X-ray structure of carboxypeptidase A inhibited by a thiirane mechanism-based inhibitor.
Fernández D; Testero S; Vendrell J; Avilés FX; Mobashery S
Chem Biol Drug Des; 2010 Jan; 75(1):29-34. PubMed ID: 19895506
[TBL] [Abstract][Full Text] [Related]
6. A noncanonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the Tri-Kunitz SmCI in complex with human CPA4.
Alonso del Rivero M; Reytor ML; Trejo SA; Chávez MA; Avilés FX; Reverter D
Structure; 2013 Jul; 21(7):1118-26. PubMed ID: 23746805
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
Sivaraman J; Nägler DK; Zhang R; Ménard R; Cygler M
J Mol Biol; 2000 Jan; 295(4):939-51. PubMed ID: 10656802
[TBL] [Abstract][Full Text] [Related]
8. Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking.
Mouradov D; Craven A; Forwood JK; Flanagan JU; García-Castellanos R; Gomis-Rüth FX; Hume DA; Martin JL; Kobe B; Huber T
Protein Eng Des Sel; 2006 Jan; 19(1):9-16. PubMed ID: 16249216
[TBL] [Abstract][Full Text] [Related]
9. 3D structure of Sulfolobus solfataricus carboxypeptidase developed by molecular modeling is confirmed by site-directed mutagenesis and small angle X-ray scattering.
Occhipinti E; Martelli PL; Spinozzi F; Corsi F; Formantici C; Molteni L; Amenitsch H; Mariani P; Tortora P; Casadio R
Biophys J; 2003 Aug; 85(2):1165-75. PubMed ID: 12885660
[TBL] [Abstract][Full Text] [Related]
10. Native carboxypeptidase A in a new crystal environment reveals a different conformation of the important tyrosine 248.
Bukrinsky JT; Bjerrum MJ; Kadziola A
Biochemistry; 1998 Nov; 37(47):16555-64. PubMed ID: 9843422
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of novel metallocarboxypeptidase inhibitor from marine mollusk Nerita versicolor in complex with human carboxypeptidase A4.
Covaleda G; del Rivero MA; Chávez MA; Avilés FX; Reverter D
J Biol Chem; 2012 Mar; 287(12):9250-8. PubMed ID: 22294694
[TBL] [Abstract][Full Text] [Related]
12. The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.
García-Sáez I; Reverter D; Vendrell J; Avilés FX; Coll M
EMBO J; 1997 Dec; 16(23):6906-13. PubMed ID: 9384570
[TBL] [Abstract][Full Text] [Related]
13. Three high-resolution crystal structures of cadmium-substituted carboxypeptidase A provide insight into the enzymatic function.
Jensen F; Bukrinsky T; Bjerrum J; Larsen S
J Biol Inorg Chem; 2002 Apr; 7(4-5):490-9. PubMed ID: 11941507
[TBL] [Abstract][Full Text] [Related]
14. Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin.
García-Castellanos R; Bonet-Figueredo R; Pallarés I; Ventura S; Avilés FX; Vendrell J; Gomis-Rütha FX
Cell Mol Life Sci; 2005 Sep; 62(17):1996-2014. PubMed ID: 16091843
[TBL] [Abstract][Full Text] [Related]
15. Structure of the carboxypeptidase Y inhibitor IC in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction.
Mima J; Hayashida M; Fujii T; Narita Y; Hayashi R; Ueda M; Hata Y
J Mol Biol; 2005 Mar; 346(5):1323-34. PubMed ID: 15713484
[TBL] [Abstract][Full Text] [Related]
16. Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Reverter D; Fernández-Catalán C; Baumgartner R; Pfänder R; Huber R; Bode W; Vendrell J; Holak TA; Avilés FX
Nat Struct Biol; 2000 Apr; 7(4):322-8. PubMed ID: 10742178
[TBL] [Abstract][Full Text] [Related]
17. Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.
Bayés A; Fernández D; Solà M; Marrero A; García-Piqué S; Avilés FX; Vendrell J; Gomis-Rüth FX
Biochemistry; 2007 Jun; 46(23):6921-30. PubMed ID: 17506531
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation.
Gomis-Rüth FX; Gómez-Ortiz M; Vendrell J; Ventura S; Bode W; Huber R; Avilés FX
J Mol Biol; 1997 Jun; 269(5):861-80. PubMed ID: 9223647
[TBL] [Abstract][Full Text] [Related]
19. Comparative study on activation mechanism of carboxypeptidase A1, A2 and B: first insights from steered molecular dynamics simulations.
Jitonnom J; Sontag C
J Mol Graph Model; 2012 Sep; 38():298-303. PubMed ID: 23085168
[TBL] [Abstract][Full Text] [Related]
20. Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843.
Wolfe LA; Mullin RJ; Laethem R; Blumenkopf TA; Cory M; Miller JF; Keith BR; Humphreys J; Smith GK
Bioconjug Chem; 1999; 10(1):38-48. PubMed ID: 9893962
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
