BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 18572410)

  • 1. Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity.
    Tavori H; Khatib S; Aviram M; Vaya J
    Bioorg Med Chem; 2008 Aug; 16(15):7504-9. PubMed ID: 18572410
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase.
    Khersonsky O; Tawfik DS
    Biochemistry; 2005 Apr; 44(16):6371-82. PubMed ID: 15835926
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico analyses of substrate interactions with human serum paraoxonase 1.
    Hu X; Jiang X; Lenz DE; Cerasoli DM; Wallqvist A
    Proteins; 2009 May; 75(2):486-98. PubMed ID: 18951406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Paraoxonase 1 attenuates human plaque atherogenicity: relevance to the enzyme lactonase activity.
    Tavori H; Vaya J; Aviram M
    Adv Exp Med Biol; 2010; 660():99-111. PubMed ID: 20221874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1.
    Ben-David M; Elias M; Filippi JJ; Duñach E; Silman I; Sussman JL; Tawfik DS
    J Mol Biol; 2012 May; 418(3-4):181-96. PubMed ID: 22387469
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lactonases with organophosphatase activity: structural and evolutionary perspectives.
    Draganov DI
    Chem Biol Interact; 2010 Sep; 187(1-3):370-2. PubMed ID: 20122908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differences in amino acid residues in the binding pockets dictate substrate specificities of mouse senescence marker protein-30, human paraoxonase1, and squid diisopropylfluorophosphatase.
    Belinskaya T; Pattabiraman N; diTargiani R; Choi M; Saxena A
    Biochim Biophys Acta; 2012 May; 1824(5):701-10. PubMed ID: 22401958
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases.
    Khersonsky O; Tawfik DS
    J Biol Chem; 2006 Mar; 281(11):7649-56. PubMed ID: 16407305
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1).
    Renault F; Carus T; Cléry-Barraud C; Elias M; Chabrière E; Masson P; Rochu D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(17-18):1346-55. PubMed ID: 19945920
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters.
    Billecke S; Draganov D; Counsell R; Stetson P; Watson C; Hsu C; La Du BN
    Drug Metab Dispos; 2000 Nov; 28(11):1335-42. PubMed ID: 11038162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192.
    Aggarwal G; Prajapati R; Tripathy RK; Bajaj P; Iyengar AR; Sangamwar AT; Pande AH
    PLoS One; 2016; 11(2):e0147999. PubMed ID: 26829396
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stabilization of the active form(s) of human paraoxonase by human phosphate-binding protein.
    Rochu D; Chabrière E; Renault F; Elias M; Cléry-Barraud C; Masson P
    Biochem Soc Trans; 2007 Dec; 35(Pt 6):1616-20. PubMed ID: 18031277
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tandem purification of two HDL-associated partner proteins in human plasma, paraoxonase (PON1) and phosphate binding protein (HPBP) using hydroxyapatite chromatography.
    Renault F; Chabrière E; Andrieu JP; Dublet B; Masson P; Rochu D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 May; 836(1-2):15-21. PubMed ID: 16595195
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Towards Understanding the Catalytic Mechanism of Human Paraoxonase 1: Experimental and In Silico Mutagenesis Studies.
    Tripathy RK; Aggarwal G; Bajaj P; Kathuria D; Bharatam PV; Pande AH
    Appl Biochem Biotechnol; 2017 Aug; 182(4):1642-1662. PubMed ID: 28161867
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning.
    Rochu D; Chabrière E; Masson P
    Toxicology; 2007 Apr; 233(1-3):47-59. PubMed ID: 17007987
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.
    Harel M; Aharoni A; Gaidukov L; Brumshtein B; Khersonsky O; Meged R; Dvir H; Ravelli RB; McCarthy A; Toker L; Silman I; Sussman JL; Tawfik DS
    Nat Struct Mol Biol; 2004 May; 11(5):412-9. PubMed ID: 15098021
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into the Lactonase Mechanism of Serum Paraoxonase 1 (PON1): Experimental and Quantum Mechanics/Molecular Mechanics (QM/MM) Studies.
    Le QA; Kim S; Chang R; Kim YH
    J Phys Chem B; 2015 Jul; 119(30):9571-85. PubMed ID: 26146888
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human carotid plaque phosphatidylcholine specifically interacts with paraoxonase 1, increases its activity, and enhances its uptake by macrophage at the expense of its binding to HDL.
    Cohen E; Aviram M; Khatib S; Artoul F; Rabin A; Mannheim D; Karmeli R; Salamon T; Vaya J
    Free Radic Biol Med; 2014 Nov; 76():14-24. PubMed ID: 25091896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C).
    Tamamura H; Sigano DM; Lewin NE; Peach ML; Nicklaus MC; Blumberg PM; Marquez VE
    J Med Chem; 2004 Sep; 47(20):4858-64. PubMed ID: 15369389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Macrophage paraoxonase 1 (PON1) binding sites.
    Efrat M; Aviram M
    Biochem Biophys Res Commun; 2008 Nov; 376(1):105-10. PubMed ID: 18762170
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.