180 related articles for article (PubMed ID: 1857337)
1. 5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors.
Evans JF; Lévillé C; Mancini JA; Prasit P; Thérien M; Zamboni R; Gauthier JY; Fortin R; Charleson P; MacIntyre DE
Mol Pharmacol; 1991 Jul; 40(1):22-7. PubMed ID: 1857337
[TBL] [Abstract][Full Text] [Related]
2. 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors.
Mancini JA; Prasit P; Coppolino MG; Charleson P; Leger S; Evans JF; Gillard JW; Vickers PJ
Mol Pharmacol; 1992 Feb; 41(2):267-72. PubMed ID: 1538707
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a 5-lipoxygenase-activating protein binding assay: correlation of affinity for 5-lipoxygenase-activating protein with leukotriene synthesis inhibition.
Charleson S; Prasit P; Léger S; Gillard JW; Vickers PJ; Mancini JA; Charleson P; Guay J; Ford-Hutchinson AW; Evans JF
Mol Pharmacol; 1992 May; 41(5):873-9. PubMed ID: 1588922
[TBL] [Abstract][Full Text] [Related]
4. A new class of leukotriene biosynthesis inhibitor: the development of MK-0591.
Prasit P; Belley M; Blouin M; Brideau C; Chan C; Charleson S; Evans JF; Frenette R; Gauthier JY; Guay J
J Lipid Mediat; 1993; 6(1-3):239-44. PubMed ID: 8357985
[TBL] [Abstract][Full Text] [Related]
5. Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors.
Vickers PJ; Adam M; Charleson S; Coppolino MG; Evans JF; Mancini JA
Mol Pharmacol; 1992 Jul; 42(1):94-102. PubMed ID: 1635556
[TBL] [Abstract][Full Text] [Related]
6. FLAP: a novel drug target for inhibiting the synthesis of leukotrienes.
Ford-Hutchinson AW
Trends Pharmacol Sci; 1991 Feb; 12(2):68-70. PubMed ID: 2024291
[TBL] [Abstract][Full Text] [Related]
7. Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors.
Kargman S; Prasit P; Evans JF
J Biol Chem; 1991 Dec; 266(35):23745-52. PubMed ID: 1748650
[TBL] [Abstract][Full Text] [Related]
8. Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor.
Brideau C; Chan C; Charleson S; Denis D; Evans JF; Ford-Hutchinson AW; Fortin R; Gillard JW; Guay J; Guévremont D
Can J Physiol Pharmacol; 1992 Jun; 70(6):799-807. PubMed ID: 1330258
[TBL] [Abstract][Full Text] [Related]
9. BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly.
Garscha U; Voelker S; Pace S; Gerstmeier J; Emini B; Liening S; Rossi A; Weinigel C; Rummler S; Schubert US; Scriba GK; Çelikoğlu E; Çalışkan B; Banoglu E; Sautebin L; Werz O
Biochem Pharmacol; 2016 Nov; 119():17-26. PubMed ID: 27592027
[TBL] [Abstract][Full Text] [Related]
10. Structural requirements for the binding of fatty acids to 5-lipoxygenase-activating protein.
Charleson S; Evans JF; Léger S; Perrier H; Prasit P; Wang Z; Vickers PJ
Eur J Pharmacol; 1994 May; 267(3):275-80. PubMed ID: 8088366
[TBL] [Abstract][Full Text] [Related]
11. 5-lipoxygenase-activating protein is an arachidonate binding protein.
Mancini JA; Abramovitz M; Cox ME; Wong E; Charleson S; Perrier H; Wang Z; Prasit P; Vickers PJ
FEBS Lett; 1993 Mar; 318(3):277-81. PubMed ID: 8440384
[TBL] [Abstract][Full Text] [Related]
12. Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis.
Gür ZT; Çalışkan B; Banoglu E
Eur J Med Chem; 2018 Jun; 153():34-48. PubMed ID: 28784429
[TBL] [Abstract][Full Text] [Related]
13. Amino acid residues of 5-lipoxygenase-activating protein critical for the binding of leukotriene biosynthesis inhibitors.
Vickers PJ; Adam M; Charleson S; Abramovitz M; O'Neill G; Mancini JA
J Lipid Mediat; 1993; 6(1-3):31-42. PubMed ID: 8357989
[TBL] [Abstract][Full Text] [Related]
14. Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors.
Frenette R; Hutchinson JH; Léger S; Thérien M; Brideau C; Chan CC; Charleson S; Ethier D; Guay J; Jones TR; McAuliffe M; Piechuta H; Riendeau D; Tagari P; Girard Y
Bioorg Med Chem Lett; 1999 Aug; 9(16):2391-6. PubMed ID: 10476875
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of indolylalkoxyiminoalkylcarboxylates as leukotriene biosynthesis inhibitors.
Kolasa T; Bhatia P; Brooks CD; Hulkower KI; Bouska JB; Harris RR; Bell RL
Bioorg Med Chem; 1997 Mar; 5(3):507-14. PubMed ID: 9113329
[TBL] [Abstract][Full Text] [Related]
16. Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: implications for biological regulation of 5-lipoxygenase.
Hatzelmann A; Fruchtmann R; Mohrs KH; Raddatz S; Matzke M; Pleiss U; Keldenich J; Müller-Peddinghaus R
Agents Actions; 1994 Nov; 43(1-2):64-8. PubMed ID: 7741044
[TBL] [Abstract][Full Text] [Related]
17. The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products.
Fischer L; Hornig M; Pergola C; Meindl N; Franke L; Tanrikulu Y; Dodt G; Schneider G; Steinhilber D; Werz O
Br J Pharmacol; 2007 Oct; 152(4):471-80. PubMed ID: 17704828
[TBL] [Abstract][Full Text] [Related]
18. A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells.
Kargman S; Vickers PJ; Evans JF
J Cell Biol; 1992 Dec; 119(6):1701-9. PubMed ID: 1469057
[TBL] [Abstract][Full Text] [Related]
19. The binding of leukotriene biosynthesis inhibitors to site-directed mutants of human 5-lipoxygenase-activating protein.
Mancini JA; Coppolino MG; Klassen JH; Charleson S; Vickers PJ
Life Sci; 1994; 54(9):PL137-42. PubMed ID: 8114608
[TBL] [Abstract][Full Text] [Related]
20. Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase.
Hutchinson JH; Charleson S; Evans JF; Falgueyret JP; Hoogsteen K; Jones TR; Kargman S; Macdonald D; McFarlane CS; Nicholson DW
J Med Chem; 1995 Oct; 38(22):4538-47. PubMed ID: 7473582
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
