BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

393 related articles for article (PubMed ID: 18577513)

  • 1. The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.
    He Y; Hryciw DH; Carroll ML; Myers SA; Whitbread AK; Kumar S; Poronnik P; Hooper JD
    J Biol Chem; 2008 Aug; 283(35):24000-10. PubMed ID: 18577513
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).
    He Y; Ramsay AJ; Hunt ML; Whitbread AK; Myers SA; Hooper JD
    Biochem J; 2008 May; 412(1):45-55. PubMed ID: 18260827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC.
    Zhou R; Patel SV; Snyder PM
    J Biol Chem; 2007 Jul; 282(28):20207-12. PubMed ID: 17502380
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.
    Foot NJ; Dalton HE; Shearwin-Whyatt LM; Dorstyn L; Tan SS; Yang B; Kumar S
    Blood; 2008 Nov; 112(10):4268-75. PubMed ID: 18776082
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain.
    Bruce MC; Kanelis V; Fouladkou F; Debonneville A; Staub O; Rotin D
    Biochem J; 2008 Oct; 415(1):155-63. PubMed ID: 18498246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.
    Lin Q; Wang J; Childress C; Sudol M; Carey DJ; Yang W
    Mol Cell Biol; 2010 Mar; 30(6):1541-54. PubMed ID: 20086093
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response.
    Fan CD; Lum MA; Xu C; Black JD; Wang X
    J Biol Chem; 2013 Jan; 288(3):1674-84. PubMed ID: 23195959
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases.
    Jiang H; Thomas SN; Chen Z; Chiang CY; Cole PA
    J Biol Chem; 2019 Nov; 294(46):17421-17436. PubMed ID: 31578285
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation.
    Riling C; Kamadurai H; Kumar S; O'Leary CE; Wu KP; Manion EE; Ying M; Schulman BA; Oliver PM
    J Biol Chem; 2015 Sep; 290(39):23875-87. PubMed ID: 26245901
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels.
    Wilkars W; Wollberg J; Mohr E; Han M; Chetkovich DM; Bähring R; Bender RA
    FASEB J; 2014 May; 28(5):2177-90. PubMed ID: 24451387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination.
    van Bemmelen MX; Rougier JS; Gavillet B; Apothéloz F; Daidié D; Tateyama M; Rivolta I; Thomas MA; Kass RS; Staub O; Abriel H
    Circ Res; 2004 Aug; 95(3):284-91. PubMed ID: 15217910
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.
    Edwin F; Anderson K; Patel TB
    J Biol Chem; 2010 Jan; 285(1):255-64. PubMed ID: 19864419
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.
    Aleidi SM; Howe V; Sharpe LJ; Yang A; Rao G; Brown AJ; Gelissen IC
    J Biol Chem; 2015 Oct; 290(40):24604-13. PubMed ID: 26296893
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of Nedd4-1 WW domains in binding and regulating human organic anion transporter 1.
    Xu D; Wang H; Gardner C; Pan Z; Zhang PL; Zhang J; You G
    Am J Physiol Renal Physiol; 2016 Aug; 311(2):F320-9. PubMed ID: 27226107
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of Nedd4/Nedd4-like dependant ubiquitylation in epithelial transport processes.
    Flores SY; Debonneville C; Staub O
    Pflugers Arch; 2003 Jun; 446(3):334-8. PubMed ID: 12698368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca
    Li B; Hoel CM; Brohawn SG
    Nat Commun; 2021 Nov; 12(1):6913. PubMed ID: 34824283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination.
    Pak Y; Glowacka WK; Bruce MC; Pham N; Rotin D
    J Cell Biol; 2006 Nov; 175(4):631-45. PubMed ID: 17116753
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rescue of HIV-1 release by targeting widely divergent NEDD4-type ubiquitin ligases and isolated catalytic HECT domains to Gag.
    Weiss ER; Popova E; Yamanaka H; Kim HC; Huibregtse JM; Göttlinger H
    PLoS Pathog; 2010 Sep; 6(9):e1001107. PubMed ID: 20862313
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells.
    Zeng F; Xu J; Harris RC
    FASEB J; 2009 Jun; 23(6):1935-45. PubMed ID: 19193720
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.
    Rotin D; Prag G
    Physiology (Bethesda); 2024 Jan; 39(1):18-29. PubMed ID: 37962894
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.