BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 18579768)

  • 21. Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II).
    Xu D; Min Y; Cheng Q; Shi H; Wei K; Arnesano F; Natile G; Liu Y
    J Inorg Biochem; 2013 Dec; 129():15-22. PubMed ID: 24008133
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Multiple states of stalled T7 RNA polymerase at DNA lesions generated by platinum anticancer agents.
    Jung Y; Lippard SJ
    J Biol Chem; 2003 Dec; 278(52):52084-92. PubMed ID: 14534300
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.
    Kasparkova J; Suchankova T; Halamikova A; Zerzankova L; Vrana O; Margiotta N; Natile G; Brabec V
    Biochem Pharmacol; 2010 Feb; 79(4):552-64. PubMed ID: 19782655
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Conformer distribution in (cis-1,4-DACH)bis(guanosine-5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin.
    Ranaldo R; Margiotta N; Intini FP; Pacifico C; Natile G
    Inorg Chem; 2008 Apr; 47(7):2820-30. PubMed ID: 18284193
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The reaction of a platinated methionine motif of CTR1 with cysteine and histidine is dependent upon the type of precursor platinum complex.
    Ma G; Wu Q; Wu X; Arnesano F; Natile G; Sletten E; Liu Y
    J Inorg Biochem; 2015 Dec; 153():239-246. PubMed ID: 26235215
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Preparation and characterization of platinum(II) and (IV) complexes of 1,3-diaminepropane and 1,4-diaminebutane: circumvention of cisplatin resistance and DNA interstrand cross-link formation in CH1cisR ovarian tumor cells.
    Alvarez-Valdés A; Pérez JM; López-Solera I; Lannegrand R; Continente JM; Amo-Ochoa P; Camazón MJ; Solans X; Font-Bardía M; Navarro-Ranninger C
    J Med Chem; 2002 Apr; 45(9):1835-44. PubMed ID: 11960495
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mechanistic and biological characteristics of different sugar conjugated 2-methyl malonatoplatinum(II) complexes as new tumor targeting agents.
    Gao X; Liu S; Shi Y; Huang Z; Mi Y; Mi Q; Yang J; Gao Q
    Eur J Med Chem; 2017 Jan; 125():372-384. PubMed ID: 27688191
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.
    Margiotta N; Marzano C; Gandin V; Osella D; Ravera M; Gabano E; Platts JA; Petruzzella E; Hoeschele JD; Natile G
    J Med Chem; 2012 Aug; 55(16):7182-92. PubMed ID: 22788918
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cellular and molecular aspects of drugs of the future: oxaliplatin.
    Di Francesco AM; Ruggiero A; Riccardi R
    Cell Mol Life Sci; 2002 Nov; 59(11):1914-27. PubMed ID: 12530522
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inversion of the cis geometry requirement for cytotoxicity in structurally novel platinum(II) complexes containing the bidentate N,O-donor pyridin-2-yl-acetate.
    Bierbach U; Sabat M; Farrell N
    Inorg Chem; 2000 May; 39(9):1882-90. PubMed ID: 11428108
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A novel isomerization on interaction of antitumor-active azole-bridged dinuclear platinum(II) complexes with 9-ethylguanine. Platinum(II) atom migration from N2 to N3 on 1,2,3-triazole.
    Komeda S; Lutz M; Spek AL; Yamanaka Y; Sato T; Chikuma M; Reedijk J
    J Am Chem Soc; 2002 May; 124(17):4738-46. PubMed ID: 11971723
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt(II) complexes.
    Florian J; Kasparkova J; Farrell NP; Brabec V
    J Biol Inorg Chem; 2012 Feb; 17(2):187-96. PubMed ID: 21894503
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.
    Kasparkova J; Vojtiskova M; Natile G; Brabec V
    Chemistry; 2008; 14(4):1330-41. PubMed ID: 18022972
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis, structural characterization, and antitumor properties of a novel class of large-ring platinum(II) chelate complexes incorporating the cis-1,4-diaminocyclohexane ligand in a unique locked boat conformation.
    Hoeschele JD; Showalter HD; Kraker AJ; Elliott WL; Roberts BJ; Kampf JW
    J Med Chem; 1994 Aug; 37(17):2630-6. PubMed ID: 8064793
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanistic studies of a novel class of trisubstituted platinum(II) antitumor agents.
    Hollis LS; Sundquist WI; Burstyn JN; Heiger-Bernays WJ; Bellon SF; Ahmed KJ; Amundsen AR; Stern EW; Lippard SJ
    Cancer Res; 1991 Apr; 51(7):1866-75. PubMed ID: 2004370
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A potent cytotoxic photoactivated platinum complex.
    Mackay FS; Woods JA; Heringová P; Kaspárková J; Pizarro AM; Moggach SA; Parsons S; Brabec V; Sadler PJ
    Proc Natl Acad Sci U S A; 2007 Dec; 104(52):20743-8. PubMed ID: 18093923
    [TBL] [Abstract][Full Text] [Related]  

  • 37. In vitro formation of DNA adducts by cisplatin, lobaplatin and oxaliplatin in calf thymus DNA in solution and in cultured human cells.
    Saris CP; van de Vaart PJ; Rietbroek RC; Blommaert FA
    Carcinogenesis; 1996 Dec; 17(12):2763-9. PubMed ID: 9006117
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Preparation of antitumor oxaliplatin/cisplatin docking dinuclear platinum complex.
    Noji M; Kizu R; Takeda Y; Akiyama N; Yoshizaki I; Eriguchi M; Kidani Y
    Biomed Pharmacother; 2005 Jun; 59(5):224-9. PubMed ID: 15919175
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Instability of the monofunctional adducts in cis-[Pt(NH3)2(N7-N-methyl-2-diazapyrenium)Cl](2+)-modified DNA: rates of cross-linking reactions in cis-platinum-modified DNA.
    Payet D; Gaucheron F; Sip M; Leng M
    Nucleic Acids Res; 1993 Dec; 21(25):5846-51. PubMed ID: 8290343
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.
    Kostrhunova H; Vrana O; Suchankova T; Gibson D; Kasparkova J; Brabec V
    Chem Res Toxicol; 2010 Nov; 23(11):1833-42. PubMed ID: 20939593
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.